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Rhumatologue

Docteur Laetitia DIEP

📍 Doullens (80)HospitalierRPPS 10101665726
Publications actives

5 publis sur 5 ans

📊 Reconnaissance scientifique : 2/100📝 6 articles publiés📚 HAL (3)📕 1 livre

✨ Profil synthétique

IA · 05/05/2026

Le Docteur Laetitia DIEP est une rhumatologue hospitalière à Doullens, avec des recherches axées sur les thérapies de l'arthrite rhumatoïde, les biosimilaires, la santé osseuse et l'ostéoporose. Elle a publié 6 articles et possède un h-index de 2 selon OpenAlex. Ses publications sur PubMed portent notamment sur les essais cliniques et les biothérapies.

Expertises présumées

  • Arthrite rhumatoïde
  • Ostéoporose
  • Ostéoarthrite
  • Lupus érythémateux systémique
  • Thérapies anti-TNF
  • Biothérapies non anti-TNF
  • Risque cardio-vasculaire

Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.

Diplômes

🎓 DES & spécialité ordinale

  • DES Rhumatologie
  • Rhumatologie (SM)

🎓 Diplômes

  • DE Docteur en médecine

Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.

Activité de recherche & publications

Source : bases de données publiques (OpenAlex, PubMed).

h-index

2

h articles cités ≥ h fois chacun. Un h de 2 = 2 publications avec 2+ citations.

Citations

15

Publications

6

i10-index

0

Thématiques principales

  • Rheumatoid Arthritis Research and Therapies ×4
  • Biosimilars and Bioanalytical Methods ×2
  • Bone health and osteoporosis research ×1
  • Osteoarthritis Treatment and Mechanisms ×1
  • Systemic Lupus Erythematosus Research ×1

Affiliations FR : Centre Hospitalier Universitaire Amiens-Picardie

Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.

Bibliographie

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Livres & ouvrages

Source : Google Books — filtre catégories médicales/santé/sciences.

Localisation

Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.

Lieux de consultation

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

  • 1
    Intraoperative ligament laxity influences functional outcome 1 year after total knee arthroplasty

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2015

    📚 70 citations🎯 RCR 4.81Top 8% NIH🔓 Open Access📄 PDF gratuit ↗
    Lire l'abstract Crossref ↓

    AbstractPurposeTo find out if there is an association between ligament laxity measured intraoperatively and functional outcome 1 year after total knee arthroplasty (TKA).MethodsMedial and lateral ligament laxities were measured intraoperatively in extension and in 90° of flexion in 108 patients [122 knees; median age 70 (range 42–83) years]. Mechanical axes were measured preoperatively and at 1‐year follow‐up. Outcome measures were the Knee Injury and Osteoarthritis Outcome Score (KOOS), the Knee Society Clinical Rating System, the Oxford Knee Score and patient satisfaction. The relationships between laxity and outcome scores were examined by median regression analyses.ResultsPost‐operative mechanical axis had a significant effect on the association between ligament laxity and KOOS. Therefore, the material was stratified on post‐operative mechanical axis. In perfectly aligned and valgus‐aligned TKAs, there was a negative correlation between medial laxity and all subscores in KOOS. The most important regression coefficient (β) was recorded for the effect of medial laxity in extension on activities of daily living (ADLs) (β = −7.32, p < 0.001), sport/recreation (β = −6.9, p = 0.017) and pain (β = −5.9, p = 0.006), and for the effect of medial laxity in flexion on ADLs (β = −3.11, p = 0.023) and sport/recreation (β = −4.18, p = 0.042).ConclusionsIn order to improve the functional results after TKA, orthopaedic surgeons should monitor ligament laxity and mechanical axis intraoperatively and avoid medial laxity more than 2 mm in extension and 3 mm in flexion in neutral and valgus‐aligned knees.Level of evidenceII.

  • 2
    Meditative-based diaphragmatic breathing vs. vagus nerve stimulation in the treatment of fibromyalgia-A randomized controlled trial: Body vs. machine

    Frontiers in neurology · 2022

    📚 23 citations🎯 RCR 3.11Top 15% NIH🔓 Open Access📄 PDF gratuit ↗
    Lire l'abstract Crossref ↓

    ImportanceVagus nerve innervation via electrical stimulation and meditative-based diaphragmatic breathing may be promising treatment avenues for fibromyalgia.ObjectiveExplore and compare the treatment effectiveness of active and sham transcutaneous vagus nerve stimulation (tVNS) and meditative-based diaphragmatic breathing (MDB) for fibromyalgia.DesignParticipants enrolled from March 2019–October 2020 and randomly assigned to active tVNS (n = 28), sham tVNS (n = 29), active MDB (n = 29), or sham MDB (n = 30). Treatments were self-delivered at home for 15 min/morning and 15 min/evening for 14 days. Follow-up was at 2 weeks.SettingOutpatient pain clinic in Oslo, Norway.Participants116 adults aged 18–65 years with severe fibromyalgia were consecutively enrolled and randomized. 86 participants (74%) had an 80% treatment adherence and 107 (92%) completed the study at 2 weeks; 1 participant dropped out due to adverse effects from active tVNS.InterventionsActive tVNS is placed on the cymba conchae of the left ear; sham tVNS is placed on the left earlobe. Active MDB trains users in nondirective meditation with deep breathing; sham MDB trains users in open-awareness meditation with paced breathing.Main outcomes and measuresPrimary outcome was change from baseline in ultra short-term photoplethysmography-measured cardiac-vagal heart rate variability at 2 weeks. Prior to trial launch, we hypothesized that (1) those randomized to active MDB or active tVNS would display greater increases in heart rate variability compared to those randomized to sham MDB or sham tVNS after 2-weeks; (2) a change in heart rate variability would be correlated with a change in self-reported average pain intensity; and (3) active treatments would outperform sham treatments on all pain-related secondary outcome measures.ResultsNo significant across-group changes in heart rate variability were found. Furthermore, no significant correlations were found between changes in heart rate variability and average pain intensity during treatment. Significant across group differences were found for overall FM severity yet were not found for average pain intensity.Conclusions and relevanceThese findings suggest that changes in cardiac-vagal heart rate variability when recorded with ultra short-term photoplethysmography in those with fibromyalgia may not be associated with treatment-specific changes in pain intensity. Further research should be conducted to evaluate potential changes in long-term cardiac-vagal heart rate variability in response to noninvasive vagus nerve innervation in those with fibromyalgia.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/NCT03180554, Identifier: NCT03180554.

  • 3
    Does body height reduction influence interpretation of lung function in COPD patients?

    The European respiratory journal · 2010

    📚 12 citations🔓 Open Access📄 PDF gratuit ↗
    Lire l'abstract Crossref ↓

    Vertebral deformities are prevalent in chronic obstructive pulmonary disease (COPD) patients and may cause excessive loss of height. As height is used for calculating reference values for pulmonary function tests, larger than normal height reduction could cause overestimation of lung function. In this cross-sectional study of 465 COPD patients and 462 controls, we explored how often lung function is misinterpreted due to height reduction in COPD patients, and whether the number or severity of vertebral deformities correlate with height reduction. Measured height was compared to recalled tallest height (RTH) and height calculated from arm span (ASH) to assess height reduction. Vertebral deformities were assessed from radiographs and pulmonary function was assessed using standard formulae. Height reduction was frequent in both the study and control groups, and increased with the number and severity of vertebral deformities. When using current measured height, lung function was overestimated in a significant proportion of COPD patients at relatively modest height reductions. The effects were smallest for forced expiratory volume in 1 s and forced vital capacity, and most pronounced for total lung capacity and residual volume. Therefore, we propose that in COPD patients with excessive height reduction, one might use RTH or ASH in calculating predicted values. Furthermore, such patients should be evaluated for co-existing vertebral deformities and osteoporosis.

Publications scientifiques (7) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Transversal3

Essai clinique2

Anti-TNF1

Biothérapies non-anti-TNF1

Risque cardio-vasculaire1

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