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3 raisons identifiées
Auteur de référence en rhumatologie
33 articles scientifiques publiés — un praticien à la pointe de la recherche
Disponibilité géographique
2 lieux d'exercice — choisissez celui qui vous arrange
Délais de RDV courts dans la région
119.2 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
Indicateurs publics agrégés sur 250 M+ d'œuvres scientifiques (OpenAlex, PubMed). Traduits ici en langage patient.
Influence scientifique
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
67
67 articles ont été cités au moins 67fois par d'autres chercheurs — preuve que ses travaux sont repris par la communauté médicale.
h-index
Total citations reçues
19 838
Nombre de fois où d'autres équipes ont mentionné ses publications dans leurs propres travaux.
Publications totales
398
Articles, revues et chapitres référencés dans les bases académiques internationales.
Articles influents
206
Publications ayant marqué leur domaine — chacune citée au moins 10 fois par d'autres chercheurs.
i10-index
Thématiques principales
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.
Clinical Criteria for the Definition of Refractory Septic Shock: A Joint Delphi Consensus from the Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM)
2026ArticleCritical Care Medicine
Dynamin independent endocytosis is an alternative cell entry mechanism for multiple animal viruses
2024ArticlePLoS Pathogens
Hypothermia vs Normothermia in Patients With Cardiac Arrest and Nonshockable Rhythm
2023ArticleJAMA neurology
Correction: Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial
2023ArticleIntensive Care Medicine
A Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial
2022ArticleCritical Care
Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial
2022ArticleCritical Care
Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial
2022ArticleIntensive Care Medicine
The Effect of an Accelerated Renal Replacement Therapy Initiation Is Not Modified by Baseline Risk
2022ArticleAnnals of the American Thoracic Society
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
CABINET DU DR PAUL YOUNG
41 C RUE DU CHAMP DES OISEAUX, 76000 ROUEN
SOCIETE NATIONALE SNCF
SNCF ST DENIS 2 PL AUX ETOILES 2 PL AUX ETOILES, 93210 SAINT DENIS
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
JAMA · 2025
ImportanceGuidelines recommend augmenting enteral protein during critical illness, but the impact on patient outcomes is uncertain.ObjectiveTo determine whether augmenting enteral protein increases days alive and free from hospitalization.Design, Setting, and ParticipantsThis cluster randomized, crossover, open-label trial recruited critically ill patients receiving enteral nutrition from 8 intensive care units (ICUs) in Australia and New Zealand from May 23, 2022, to August 23, 2023, with final follow-up on November 21, 2023.InterventionTwo isocaloric enteral formulae were compared: augmented protein (100 g protein/L) vs usual protein (63 g protein/L). ICUs used formulae sequentially for 3 months over a 12-month period; 4 ICUs commenced with augmented protein and 4 commenced with usual protein.Main Outcomes and MeasuresThe primary outcome was the number of days free of admittance to the index hospital and alive at day 90. Secondary outcomes included days free of the index hospital at day 90 in survivors; alive at day 90; durations of invasive ventilation, ICU, and hospital admission; incidences of tracheostomy insertion and new kidney replacement therapy; and hospital discharge destination.ResultsA total of 3397 patients were included (median [IQR] age, 61 (48-71) years; 2157 [64%] male). The median (IQR) number of days free of the index hospital and alive at day 90 was 62 (0-77) days in the augmented protein group and 64 (0-77) days in the usual protein group, with an adjusted-for-period between-group median difference of −1.97 (95% CI, −7.24 to 3.30) days (P = .46). At day 90, a total of 1221 of 1681 patients (72.6%) were alive in the augmented protein group and 1269 of 1716 (74.0%) were alive in the usual protein group (risk ratio, 0.99 [95% CI, 0.95-1.03]). Between-group differences for secondary outcomes included the following: difference in median days free of hospital in survivors, 0.01 (95% CI, −1.94 to 1.96) days; difference in mean duration of invasive ventilation, 6.8 (95% CI, −3.0 to 16.5) hours; cause-specific hazard ratios for durations of ICU admission (time to live ICU discharge), 0.93 (95% CI, 0.88-1.00) and hospital admission (time to live hospital discharge), 0.96 (95% CI, 0.90-1.02); and risk ratio for tracheostomy, 1.15 (95% CI, 0.66-2.01) and new kidney replacement therapy, 0.97 (95% CI, 0.81-1.16). Discharge destinations were similar.Conclusions and RelevanceAugmenting enteral protein during critical illness did not improve number of days free of the index hospital and alive at day 90.Trial RegistrationANZCTR Identifier: ACTRN12621001484831
JAMA · 2025
ImportanceSupplemental oxygen is frequently given to patients in intensive care units (ICUs); however, there is insufficient evidence to guide its therapeutic use and to minimize the potential harm caused by administering too little or too much.ObjectiveTo determine whether reducing exposure to supplemental oxygen through a strategy of conservative oxygen therapy by using a peripheral oxygen saturation (Spo2) target of 90% (range, 88%-92%) reduces mortality at 90 days in mechanically ventilated adult patients receiving supplemental oxygen in the ICU.Design, Setting, and ParticipantsMulticenter, pragmatic, randomized clinical trial conducted in 97 ICUs in the UK including 16 500 mechanically ventilated patients receiving supplemental oxygen. Participants were enrolled between May 2021 and November 2024. Follow-up was completed in February 2025.InterventionsParticipants randomized to conservative oxygen therapy (n = 8258) received the lowest fraction of inspired oxygen possible to maintain their Spo2 at 90%. Participants randomized to usual oxygen therapy (n = 8242) received oxygen therapy at the discretion of the treating clinician.Main Outcomes and MeasuresThe primary outcome was all-cause mortality at 90 days. Secondary outcomes included duration of ICU and acute hospital stay among survivors, days alive and free from organ support at 30 days, and mortality at other time points.ResultsOf 16 500 randomized patients, primary outcome data were available for 16 394 (8211 in the conservative and 8183 in the usual oxygen therapy group). Randomized groups were similar (median age, 60 [IQR, 48-71] years and 38.2% females in both groups [n = 5652]). Exposure to supplemental oxygen was 29% lower for participants in the conservative oxygen therapy group compared with the usual oxygen therapy group. By 90 days, 2908 participants (35.4%) in the conservative oxygen therapy group had died compared with 2858 (34.9%) in the usual oxygen therapy group. After adjustment for prespecified baseline variables, the risk difference was 0.7 percentage points (95% CI, −0.7 to 2.0; P = .28). There were no significant differences in durations in ICU or hospital stay, days alive and free from organ support at 30 days, or mortality at other time points.Conclusions and RelevanceIn adult patients receiving mechanical ventilation and supplemental oxygen in the ICU, minimizing oxygen exposure through conservative oxygen therapy did not significantly reduce all-cause mortality at 90 days.Trial Registrationisrctn.org Identifier: ISRCTN13384956
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
American journal of respiratory and critical care medicine · 2026 · Journal Article
Serpa Neto A, Bailey M, Seller D, Agli A, et al.
The New England journal of medicine · 2026 · Journal Article
SuDDICU Investigators for the Australia and New Zealand Intensive Care Society Clinical Trials Group and the Canadian Critical Care Trials Group, Cuthbertson BH, Billot L, Campbell MK, et al.
Clinical rheumatology · 2026 · Journal Article
Emad Y, Gheita T, Ragab Y, Hammam N, et al.
Trends in cardiovascular medicine · 2026 · Journal Article
Tang DCY, Salter RJK, Chatfield AG, Young PJ, et al.
Journal of medical ethics · 2026 · Journal Article
Parker J, Hodson N, Young P, Shelton C
Intensive care medicine · 2026 · Editorial
Sekhon MS, Robba C, Young PJ
Journal of critical care · 2026 · Journal Article
Zampieri FG, Young PJ, Bernard SA, Burns B, et al.
Intensive care medicine · 2026 · Journal Article
Hodgson CL, Spicer AB, Broadley T, Bailey M, et al.
Intensive care medicine · 2025 · Journal Article
Göbel Andertun S, Wissendorff-Ekdahl A, Ullén S, Cronberg T, et al.
Intensive care medicine · 2025 · Journal Article
Poole AP, Chaba A, Bellomo R, Bailey M, et al.
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2025 · Journal Article
White KC, Laupland KB, Saxena M, Crichton B, et al.
Journal of advanced nursing · 2025 · Journal Article
Mackle DM, Nelson K, Beasley RW, Eathorne A, et al.
Acta anaesthesiologica Scandinavica · 2025 · Journal Article
Lilja G, Töniste D, Bass F, Jakobsen JC, et al.
Resuscitation · 2025 · Journal Article
Lagebrant A, Sandroni C, Nolan JP, Bělohlávek J, et al.
American journal of respiratory and critical care medicine · 2025 · Journal Article
Deane AM, Lauzier F, Adhikari NKJ, Lamontagne F, et al.
Australian critical care : official journal of the Confederation of Australian Critical Care Nurses · 2026 · Journal Article
Mackle D, Beasley R, Eathorne A, Nelson K, et al.
JAMA neurology · 2026 · Journal Article
Hultgren M, Blennow Nordström E, Ullén S, Nielsen N, et al.
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026 · Journal Article
Hughes-Gooding T, Baggio D, Litton E, Pilcher D, et al.
Australian critical care : official journal of the Confederation of Australian Critical Care Nurses · 2026 · Journal Article
Thompson K, Haines K, Chaba A, Poole AP, et al.
Circulation · 2026 · Journal Article
D'Ambrosio P, De Paepe J, Spencer LW, Ohanian M, et al.
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2025 · Journal Article
Crichton BB, Eathorne A, Coombes J, Edwards C, et al.
Critical care medicine · 2026 · Journal Article
Leone M, Myatra SN, Dugar S, Wieruszewski PM, et al.
British journal of anaesthesia · 2026 · Journal Article
De Cassai A, Dost B, Augoustides JG, Azamfirei L, et al.
Intensive care medicine · 2026 · Journal Article
Leone M, Myatra SN, Dugar S, Wieruszewski PM, et al.
British journal of anaesthesia · 2026 · Journal Article
De Cassai A, Dost B, Augoustides JG, Azamfirei L, et al.
Orthopedic reviews · 2026 · Journal Article
Kye B, Foster C, Young P
JCPP advances · 2025 · Journal Article
Mughal F, Young P, Stahl D, Asarnow JR, et al.
Critical care medicine · 2025 · Journal Article
Higgins AM, Lee YY, Bailey M, Bellomo R, et al.
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026 · Journal Article
Orford N, Serpa Neto A, Nair P, Bone A, et al.
The Journal of infectious diseases · 2026 · Journal Article
Chappell KJ, Mordant FL, Amarilla AA, Modhiran N, et al.
JCPP advances · 2025 · Journal Article
Mughal F, Young P, Stahl D, Asarnow JR, et al.
Critical care medicine · 2025 · Journal Article
Higgins AM, Lee YY, Bailey M, Bellomo R, et al.
CCDC 932215: Experimental Crystal Structure Determination
Related Article: James R. Wright, Paul C. Young, Nigel T. Lucas, Ai-Lan Lee, and James D. Crowley|2013|Organometallics|32|7065|doi:10.1021/om400773n
CCDC 932211: Experimental Crystal Structure Determination
Related Article: James R. Wright, Paul C. Young, Nigel T. Lucas, Ai-Lan Lee, and James D. Crowley|2013|Organometallics|32|7065|doi:10.1021/om400773n
CCDC 914705: Experimental Crystal Structure Determination
Related Article: Paul C. Young,Samantha L. J. Green,Georgina M. Rosair,Ai-Lan Lee|2013|Dalton Trans.|42|9645|doi:10.1039/C3DT50653C
CCDC 896069: Experimental Crystal Structure Determination
Related Article: Richard J. Mudd, Paul C. Young, James A. Jordan-Hore, Georgina M. Rosair, and Ai-Lan Lee|2012|J.Org.Chem.|77|7633|doi:10.1021/jo300930c
Nutrition has a pervasive impact on cardiac microRNA expression in isogenic mice
The complex interaction between obesity, Western-style diets, and cardiovascular disease is of increasing interest, with a growing number of children being born to obese parents with poor lifestyle choices. These offspri
Highly respirable dry powder inhalable formulation of voriconazole with enhanced pulmonary bioavailability
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).
The Journal of infectious diseases · 2026 · Journal Article
Chappell KJ, Mordant FL, Amarilla AA, Modhiran N, et al.
JAMA · 2025 · Journal Article
Martin DS, Gould DW, Shahid T, Doidge JC, et al.
JAMA · 2025 · Journal Article
Summers MJ, Chapple LS, Karahalios A, Bellomo R, et al.
Australian critical care : official journal of the Confederation of Australian Critical Care Nurses · 2025 · Journal Article
Sultana S, Chaba A, Jenney A, Young PJ, et al.
Resuscitation · 2025 · Journal Article
Lagebrant A, Lee BK, Youn CS, Sandroni C, et al.