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4 raisons identifiées
Plateau technique de référence
Assistance publique – Hôpitaux de Paris (APHP) — équipements et expertise pointus pour les cas complexes
Auteur de référence en rhumatologie
36 articles scientifiques publiés — un praticien à la pointe de la recherche
Disponibilité géographique
2 lieux d'exercice — choisissez celui qui vous arrange
Délais de RDV courts dans la région
150.8 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CABINET DU DR Kim WEGENER
CLINIQUE NOTRE DAME 23 RUE DES ACRES, 14500 VIRE
GHU APHP SUN SITE PITIE SALPETRIERE
47-83 47 BD DE L HOPITAL, 75651 PARIS CEDEX 13
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Arthritis and rheumatism · 2003
AbstractObjectiveTo identify and recombine a protein of the human dermal microvascular endothelial cell (HDMEC) that specifically reacts with anti–endothelial cell antibody (AECA) in the serum of patients with Behçet's disease (BD), and to evaluate the usefulness of this protein in BD.MethodsThe proteomics technique, with 2‐dimensional gel electrophoresis and matrix‐assisted laser desorption ionization−time‐of‐flight (MALDI‐TOF) mass spectrometry, was used to identify and recombine HDMEC antigen. Western blotting and enzyme‐linked immunosorbent assay (ELISA) of recombinant protein isolated by gene cloning were performed on serum from healthy controls, patients with BD, and patients with other rheumatic diseases (rheumatoid arthritis, systemic lupus erythematosus, and Wegener's granulomatosis).ResultsEighteen of 40 BD patients had serum IgM antibody to HDMEC antigen. The purified protein that reacted with AECA in BD patient sera was found to be α‐enolase by 2‐dimensional gel electrophoresis followed by immunoblotting and MALDI‐TOF mass spectrometry. Recombinant α‐enolase protein was isolated and refined by gene cloning. On Western blots, AECA‐positive IgM from the sera of patients with active BD reacted strongly with recombinant human α‐enolase. BD patient sera positive for anti–α‐enolase did not react with human γ‐enolase. On dot‐blotting, reactivity to human α‐enolase was detected only in the IgM‐positive group. Fifteen of the 18 AECA‐positive sera that were positive for the HDMEC antigen showed reactivity to recombinant α‐enolase IgM antibody by ELISA.ConclusionThe α‐enolase protein is the target protein of serum AECA in BD patients. This is the first report of the presence of IgM antibodies to α‐enolase in endothelial cells from the serum of BD patients. Although further studies relating this protein to the pathogenesis of BD will be necessary, α‐enolase and its antibody may prove useful in the development of new diagnostic and treatment modalities in BD.
Arthritis and rheumatism · 2009
AbstractObjectiveTo compare the criteria for Wegener's granulomatosis (WG) of the American College of Rheumatology (ACR) with those of the European League Against Rheumatism/Pediatric Rheumatology European Society (EULAR/PRES) in a cohort of children with WG and other antineutrophil cytoplasmic antibody (ANCA)–associated vasculitides (AAVs), and to describe the interval to diagnosis, presenting features, and initial treatment for WG.MethodsEligible patients had been diagnosed by site rheumatologists (termed the “MD diagnosis”) since 2004. This diagnosis was used as a reference standard for sensitivity and specificity testing of the 2 WG classification criteria. Descriptive analyses were confined to ACR‐classified WG patients.ResultsMD diagnoses of 117 patients (82 of whom were female) were WG (n = 76), microscopic polyangiitis (n = 17), ANCA‐positive pauci‐immune glomerulonephritis (n = 5), Churg‐Strauss syndrome (n = 2), and unclassified vasculitis (n = 17). The sensitivities of the ACR and EULAR/PRES classification criteria for WG among the spectrum of AAVs were 68.4% and 73.6%, respectively, and the specificities were 68.3% and 73.2%, respectively. Two more children were identified as having WG by the EULAR/PRES criteria than by the ACR criteria. For the 65 ACR‐classified WG patients, the median age at diagnosis was 14.2 years (range 4–17 years), and the median interval from symptom onset to diagnosis was 2.7 months (range 0–49 months). The most frequent presenting features by organ system were constitutional (89.2%), pulmonary (80.0%), ear, nose, and throat (80.0%), and renal (75.4%). Fifty‐four patients (83.1%) commenced treatment with the combination of corticosteroids and cyclophosphamide, with widely varying regimens; the remainder received methotrexate alone (n = 1), corticosteroids alone (n = 4), or a combination (n = 6).ConclusionThe EULAR/PRES criteria minimally improved diagnostic sensitivity and specificity for WG among a narrow spectrum of children with AAVs. Diagnostic delays may result from poor characterization of childhood WG. Initial therapy varied considerably among participating centers.
Radiographics : a review publication of the Radiological Society of North America, Inc · 2000
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Cureus · 2024 · Case Reports
Kim L, Shirazi M
Arthritis & rheumatology (Hoboken, N.J.) · 2016 · Comparative Study
Cabral DA, Canter DL, Muscal E, Nanda K, et al.
Journal of periodontal & implant science · 2015 · Case Reports
Sung IY, Kim YM, Cho YC, Son JH
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2013 · Case Reports
Kim SD, Kim GW, Kim TE, Nam EJ, et al.
Journal of Korean medical science · 2013 · Case Reports
Kim SH, Park J, Bae JH, Cho MS, et al.
Clinical and experimental nephrology · 2013 · Journal Article
Kim HW, Song YW
Modern rheumatology · 2013 · Journal Article
Kim HW, Kim JW, Im CH, Shin KC, et al.
Journal of medical case reports · 2012 · Journal Article
Cardenas-Garcia J, Farmakiotis D, Baldovino BP, Kim P
The Journal of rheumatology · 2012 · Journal Article
Morishita K, Guzman J, Chira P, Muscal E, et al.
Rheumatology international · 2012 · Case Reports
Kim MY, Bae SY, Lee M, Chung H, et al.
TheScientificWorldJournal · 2010 · Case Reports
Gmurczyk A, Ahya SN, Goldschmidt R, Kim G, et al.
Arthritis and rheumatism · 2009 · Comparative Study
Cabral DA, Uribe AG, Benseler S, O'Neil KM, et al.
Modern rheumatology · 2008 · Case Reports
Kim SY, Linton JM, Kolasinski SL
European radiology · 2003 · Journal Article
Lee KS, Kim TS, Fujimoto K, Moriya H, et al.
Yonsei medical journal · 2001 · Journal Article
Park YB, Kim JY, Linton JA, Jung HJ, et al.
Clinical rheumatology · 2000 · Case Reports
Song YH, Kim TH, Lee IH, Yang SC, et al.
Nihon Kyobu Shikkan Gakkai zasshi · 1994 · Case Reports
Hashimoto K, Hamamoto Y, Taniguchi T, Kumon M, et al.
Nihon Kyobu Shikkan Gakkai zasshi · 1991 · Case Reports
Kim YC, Taniguchi T, Kawarazaki S, Takasu K
Frontiers in medicine · 2025 · Case Reports
Kim Y, Woo T, Lee SU, Park E, et al.
Medicina (Kaunas, Lithuania) · 2024 · Case Reports
Lee J, Choi J, Yu SY, Kim K
Radiology case reports · 2021 · Case Reports
Lakhani DA, Balar AB, Adelanwa A, Gross A, et al.
bioRxiv : the preprint server for biology · 2024 · Journal Article
Jang HJ, Urrutia G, Orskov AD, Kim HJ, et al.
Case reports in ophthalmological medicine · 2018 · Case Reports
Kim DD, Ghorayeb G
Rheumatology international · 2016 · Case Reports
Lee IH, Kang GW, Kim KC
Modern rheumatology · 2016 · Case Reports
Cheon YH, Kim MG, Kim JE, Ha CY, et al.
Frontiers in medicine · 2025 · Case Reports
Kim Y, Woo T, Lee SU, Park E, et al.
Radiology case reports · 2021 · Case Reports
Lakhani DA, Balar AB, Adelanwa A, Gross A, et al.
Radiographics : a review publication of the Radiological Society of North America, Inc · 2000 · Journal Article
Ha HK, Lee SH, Rha SE, Kim JH, et al.
Expert opinion on biological therapy · 2023 · Observational Study
Jo JC, Jeon Y, Kim D, Yang DH, et al.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2014 · Journal Article
Malm IJ, Mener DJ, Kim J, Seo P, et al.
Stroke · 2025 · Journal Article
Xie JS, Zaslavsky K, Chaban YV, Lusterio A, et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2015 · Journal Article
Lee YH, Bae SC, Seo YH, Kim JH, et al.
IEEE transactions on medical imaging · 2024 · Journal Article
Park J, Chledowski J, Jastrzebski S, Witowski J, et al.
Stroke · 2026 · Journal Article
Salerno A, Dunet V, Sykora M, Baumgartner P, et al.
Arthritis and rheumatism · 2003 · Journal Article
Lee KH, Chung HS, Kim HS, Oh SH, et al.
World journal of clinical cases · 2021 · Case Reports
Cho U, Kim SK, Ko JM, Yoo J
Clinical imaging · 2017 · Case Reports
Kim YR, Lee YH, Lee JH, Yoon KH
Journal of Korean medical science · 2010 · Case Reports
Kim JH, Joo YB, Kim J, Min JK