📇 Rhumatologue · VERNEUIL SUR SEINE · (78) · Libéral
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2 raisons identifiées
Praticien-chercheur
14 articles scientifiques publiés — formation continue solide
Délais de RDV courts dans la région
86.1 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CABINET DU DR FABIENNE VUERINGS
45 GRAND RUE, 78480 VERNEUIL SUR SEINE
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
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European journal of cancer (Oxford, England : 1990) · 2020
Journal of neurology · 2007
Lupus · 2008
Mycophenolate mofetil (MMF) with prednisolone has been associated with high remission rates when used as induction treatment for lupus nephritis. This prospective, multicentre, cohort study investigates the efficacy and safety of this regimen over 24 weeks in 213 Chinese patients with active lupus nephritis (Classes III, IV, V or combination). Baseline activity index (AI) was 6.91 ± 3.33 and chronicity index (CI) was 1.9 ± 1.2. The remission rate was 82.6% at 24 weeks (complete remission, 34.3%; partial remission, 48.4%). There were significant ( P < 0.01) improvements in kidney function shown by reductions in proteinuria, serum albumin, serum creatinine and creatinine clearance, as well as in systemic lupus erythematosus disease activity index (SLEDAI) scores. Independent risk factors influencing remission were pathological classification (including Class V and III or Class V and IV nephritis) and elevated serum creatinine at baseline (OR 2.967, 95% CI: 1.479–6.332, P = 0.001 and OR 1.007, 95% CI: 1.002–1.011, P = 0.001, respectively). Patients with concomitant membranous features on biopsy had a lower remission rate than those with Class III and IV nephritis (66.7% vs 87.3%, P = 0.002). Renal biopsy was repeated in 25 patients following treatment. There was a transition to less severe pathological morphologies in majority of subjects. Infections were monitored throughout treatment: eight patients (3.8%) experienced bacterial infections, whereas herpes zoster occurred in seven patients. Nine patients (4.2%) suffered from gastrointestinal upset, which resolved without discontinuation of MMF. One patient became leucopenic, whereas another died from active disease unrelated to kidney symptoms. MMF combined with prednisolone is an effective and well-tolerated induction treatment for patients with active lupus nephritis and for controlling SLE systemic activity.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Drug design, development and therapy · 2019 · Journal Article
Kameoka Y, F K, M K
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie · 2011 · Case Reports
Annabel M, Hubert L, Jacques C, Fabienne L, et al.
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie · 2009 · Case Reports
Annabel M, Hubert L, Jacques C, Fabienne L, et al.
Journal of neurology · 2007 · Journal Article
Alice N, Fabienne C, Anne-Marie W, Kaat D
The Journal of surgical research · 2005 · Journal Article
Collange O, Fabienne T, Nathalie R, Christian T, et al.
Frontiers in psychiatry · 2022 · Journal Article
Nadia H, Fabienne M, Pierard C, Nicole M, et al.
Lupus · 2008 · Clinical Trial
F L, Y T, X P, L W, et al.
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024 · Journal Article
Abbas M, Patrizia C, Fabienne M, Marc B, et al.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2011 · Comment
Fabienne D, Hilde B, Bart M
The Pan African medical journal · 2024 · Journal Article
Prince Kasongo M, Philippa E, Fabienne WH, Marylyne Y, et al.
European journal of cancer (Oxford, England : 1990) · 2020 · Clinical Trial, Phase II
Hammel P, Fabienne P, Mineur L, Metges JP, et al.
BMJ case reports · 2026 · Journal Article
F A, George OK, Alex AG, Sahitya MS
Archives of public health = Archives belges de sante publique · 2015 · Journal Article
Olivier B, Serge AH, Catherine A, Jacques B, et al.
Zoo biology · 2012 · Journal Article
Fabienne D, Helen B