📇 Rhumatologue · CHARTRES CEDEX · (28) · Salarié
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2 raisons identifiées
Encadrant universitaire
Forme la prochaine génération de rhumatologues (3 thèses dirigées)
Délais de RDV courts dans la région
75.8 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
Source theses.fr — signal de direction d'équipe / statut PU-PH (à confirmer via le site universitaire).
Indicateurs publics agrégés sur 250 M+ d'œuvres scientifiques (OpenAlex, PubMed). Traduits ici en langage patient.
Influence scientifique
26
26 articles ont été cités au moins 26fois par d'autres chercheurs — preuve que ses travaux sont repris par la communauté médicale.
h-index
Total citations reçues
2 326
Nombre de fois où d'autres équipes ont mentionné ses publications dans leurs propres travaux.
Publications totales
60
Articles, revues et chapitres référencés dans les bases académiques internationales.
Articles influents
34
Publications ayant marqué leur domaine — chacune citée au moins 10 fois par d'autres chercheurs.
i10-index
Thématiques principales
Affiliations FR : Centre National de la Recherche Scientifique · Commissariat à l'Énergie Atomique et aux Énergies Alternatives · Université Paris-Saclay
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
CH CHARTRES - HÔTEL DIEU
34 R DU DOCTEUR MAUNOURY, 28018 CHARTRES CEDEX
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
The Journal of cell biology · 1994
Human autoantibodies offer unique tools for the study of cellular constituents since they usually recognize highly conserved components, the most difficult to detect due to their low immunogenicity. The serum from a patient with Sjögren's syndrome (RM serum) showing a very high reactivity to the Golgi complex has been shown to immunoprecipitate and to immunodetect by Western blotting experiments a protein mol wt 210,000 (p210) that was shown to be peripheral and cytoplasmically disposed. A close examination of the p210 labeling revealed some differences with Golgi markers: RM serum staining was slightly more extensive than several Golgi markers and showed a discontinuous or granular appearance. Nocodazole induced a specific and early segregation of many p210-associated vesicles or tubules from Golgi apparatus. Upon brefeldin A treatment, p210 did not redistribute in the ER as did other Golgi proteins. In contrast, it exhibited a vesicular pattern reminiscent to that displayed by proteins residing in the intermediate compartment. Double staining immunofluorescence using the RM serum and the marker of the intermediate compartment, p58, revealed segregation of both proteins in control conditions but colocalization in BFA-treated cells. We have further demonstrated by combining different drug treatments that p210-containing elements in brefeldin A-treated cells belong indeed to the intermediate compartment. Experiments on brefeldin A recovery suggested that these p210 elements might play a role in reformation and repositioning of the Golgi apparatus. Ultrastructural localization performed by immunoperoxidase staining allowed us to establish that p210 interacted with the external side of an abundant tubulo-vesicular system on the cis side of the Golgi complex which extended to connecting structures and vesicles between saccules or stacks of cisternae, p210 appears to be a novel protein residing in the cis-Golgi network that may cycle between the Golgi apparatus and the intermediate compartment.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
The Journal of cell biology · 1994 · Journal Article
Rios RM, Tassin AM, Celati C, Antony C, et al.
Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cγ at the centrosome-3
Lls were plated in triplicates in IL3 free medium, in the absence or presence of LY294002 10 μM, rapamycin 10 nM or equivalent amount of DMSO. Viable cells were counted over a 120 h-period. Results are means of three ind
Centrosomal nucleolin is required for microtubule network organization
Nucleolin is a pleiotropic protein involved in a variety of cellular processes. Although multipolar spindle formation has been observed after nucleolin depletion, the roles of nucleolin in centrosome regulation and funct
Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cγ at the centrosome-0
with mycFOP-FGFR1. Costaining using anti-CAP350 (green) and anti-myc (red) antibody reveals colocalization at the centrosome of CAP350 and mycFOP-FGFR1. Scale bar 5 μm. (B) FOP-FGFR1 interacts with CAP350 in lysates from
Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cγ at the centrosome-1
at the centrosome, in FOP-FGFR1-expressing Ba/F3 cells, but not in wild-type (WT) or FOP-FGFR1 kinase-defective mutant (K259A) expressing Ba/F3 cells. Scale bar 5 μm. (B) FOP-FGFR1 interacts with endogenous p85. Immunopr
Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cγ at the centrosome-5
with mycFOP-FGFR1. Costaining using anti-CAP350 (green) and anti-myc (red) antibody reveals colocalization at the centrosome of CAP350 and mycFOP-FGFR1. Scale bar 5 μm. (B) FOP-FGFR1 interacts with CAP350 in lysates from
Centrosomal nucleolin is required for microtubule network organization
Nucleolin is a pleiotropic protein involved in a variety of cellular processes. Although multipolar spindle formation has been observed after nucleolin depletion, the roles of nucleolin in centrosome regulation and funct
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).