📇 Rhumatologue · LA TRONCHE · (38) · Hospitalier
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2 raisons identifiées
Auteur de référence en rhumatologie
27 articles scientifiques publiés — un praticien à la pointe de la recherche
Délais de RDV courts dans la région
120.1 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
HOPITAL NORD - CHU38
BD DE LA CHANTOURNE, 38700 LA TRONCHE
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
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Gut · 2020
ObjectiveAgeing is accompanied by deterioration of multiple bodily functions and inflammation, which collectively contribute to frailty. We and others have shown that frailty co-varies with alterations in the gut microbiota in a manner accelerated by consumption of a restricted diversity diet. The Mediterranean diet (MedDiet) is associated with health. In the NU-AGE project, we investigated if a 1-year MedDiet intervention could alter the gut microbiota and reduce frailty.DesignWe profiled the gut microbiota in 612 non-frail or pre-frail subjects across five European countries (UK, France, Netherlands, Italy and Poland) before and after the administration of a 12-month long MedDiet intervention tailored to elderly subjects (NU-AGE diet).ResultsAdherence to the diet was associated with specific microbiome alterations. Taxa enriched by adherence to the diet were positively associated with several markers of lower frailty and improved cognitive function, and negatively associated with inflammatory markers including C-reactive protein and interleukin-17. Analysis of the inferred microbial metabolite profiles indicated that the diet-modulated microbiome change was associated with an increase in short/branch chained fatty acid production and lower production of secondary bile acids, p-cresols, ethanol and carbon dioxide. Microbiome ecosystem network analysis showed that the bacterial taxa that responded positively to the MedDiet intervention occupy keystone interaction positions, whereas frailty-associated taxa are peripheral in the networks.ConclusionCollectively, our findings support the feasibility of improving the habitual diet to modulate the gut microbiota which in turn has the potential to promote healthier ageing.
Clinics and research in hepatology and gastroenterology · 2022
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026 · Journal Article
Han ZM, Elodie WH, Zhang WJ, Xu PC, et al.
Molecules (Basel, Switzerland) · 2026 · Journal Article
Borive Amani M, Hélène MM, Ange MM, Elodie NB, et al.
Journal of translational medicine · 2026 · Journal Article
Wang L, Qi H, Zhang Y, Wei G, et al.
Journal of the American Medical Informatics Association : JAMIA · 2026 · Journal Article
E T, Li X, Liang J, Ma J, et al.
Therapeutic drug monitoring · 2026 · Journal Article
Han ZM, Elodie WH, Zhang WJ, Xu PC, et al.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025 · Journal Article
G A, C G, C J M, B L, et al.
Rheumatology (Oxford, England) · 2024 · Journal Article
Wang L, Chen S, Zhang H, Wei G, et al.
Rheumatology advances in practice · 2023 · Journal Article
Ebrahimiarjestan M, Yang L, E E, Wang T, et al.
The journal of vascular access · 2023 · Journal Article
Raphaëlle P, Elodie P, Nathalie J, Odile A, et al.
Heliyon · 2023 · Journal Article
Zheng Y, Deng J, Wang G, Zhang X, et al.
Therapeutic drug monitoring · 2022 · Journal Article
Han ZM, Elodie WH, Yan LH, Xu PC, et al.
Zhonghua zhong liu za zhi [Chinese journal of oncology] · 2020 · Journal Article
Wang RH, Xu K, Li L, Wu ZF, et al.
Zhongguo gu shang = China journal of orthopaedics and traumatology · 2020 · Journal Article
Yu QB, E ZK, Xin HW, Zhang YS, et al.
Legal medicine (Tokyo, Japan) · 2023 · Review
Nicolas D, Alain B, Eugénie C, Augusto GTP, et al.
World journal of clinical cases · 2023 · Case Reports
Fabien MB, Elodie P, Anna S, Addeo P, et al.
Journal of orthopaedic case reports · 2016 · Case Reports
Ay GR, D SR, T C, C K, et al.
Journal of oral microbiology · 2024 · Journal Article
Pilliol V, Mahmoud Abdelwadoud B, Aïcha H, Lucille T, et al.
Legal medicine (Tokyo, Japan) · 2023 · Review
Nicolas D, Alain B, Eugénie C, Augusto GTP, et al.
Medical science monitor : international medical journal of experimental and clinical research · 2020 · Journal Article
Martin VT, Abdullahi Abdi M, Li J, Li D, et al.
Journal of feline medicine and surgery · 2025 · Journal Article
Frejlich M, Grillot AE, Elodie D, Guillaume P
Medical science monitor : international medical journal of experimental and clinical research · 2020 · Journal Article
Martin VT, Abdullahi Abdi M, Li J, Li D, et al.
BMC health services research · 2025 · Journal Article
Elodie R, Leila R, Judith MF, Linda C, et al.
Magnetic resonance imaging · 2022 · Journal Article
Raolison Z, Dubois M, Luong M, Neves AL, et al.
Zhongguo shi yan xue ye xue za zhi · 2019 · Journal Article
Liu YF, He HQ, Ding YL, Wu SY, et al.
Gut · 2020 · Journal Article
Ghosh TS, Rampelli S, Jeffery IB, Santoro A, et al.
Rheumatology (Oxford, England) · 2024 · Case Reports
Sztejkowski C, Sibilia J, Danion F, Mertz P, et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026 · Consensus Statement
Fusaro M, Chandran M, Nickolas T, Ferrari S, et al.
Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry · 2025 · Journal Article
Ebrahimiarjestan M, O'sullivan M, Brennan A, E E, et al.
Clinics and research in hepatology and gastroenterology · 2022 · Journal Article
Stéphane S, Timothée W, Jérémie A, Raphael O, et al.