📇 Rhumatologue · PARIS CEDEX 20 · (75) · Hospitalier

MME PATRICIA SENET

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Plateau technique de référence
Assistance publique – Hôpitaux de Paris (APHP) — équipements et expertise pointus pour les cas complexes
Auteur de référence en rhumatologie
50 articles scientifiques publiés — un praticien à la pointe de la recherche
Délais de RDV courts dans la région
336.2 rhumatos / 100 000 hab. — département bien doté

Rhumatologue

📍 PARIS CEDEX 20 (75)HospitalierRPPS 10001442457

📊 Reconnaissance scientifique : 33/100📝 293 articles publiés🇫🇷 Publications académiques françaises (8)

✨ Génération du profil synthétique IA en cours…

Activité de recherche & publications

Indicateurs publics agrégés sur 250 M+ d'œuvres scientifiques (OpenAlex, PubMed). Traduits ici en langage patient.

Influence scientifique

Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.

Top publications · les plus citées

Circulating follicular helper T cells are increased in systemic sclerosis and promote plasmablast differentiation through the IL-21 pathway which can be inhibited by ruxolitinib

Annals of the rheumatic diseases · 2019

📚 81 citations🎯 RCR 3.23Top 15% NIH🔓 Open Access📄 PDF gratuit ↗

Treatment of calcinosis cutis in systemic sclerosis and dermatomyositis: A review of the literature

Journal of the American Academy of Dermatology · 2020

📚 54 citations🎯 RCR 4.54Top 9% NIH🔓 Open Access📄 PDF gratuit ↗

Leg Ulcers in Sickle-Cell Disease: Treatment Update

Advances in wound care · 2020

📚 25 citations🎯 RCR 2.12Top 25% NIH🔓 Open Access

Lire l'abstract Crossref ↓

Significance: Sickle-cell leg ulcers (SCLUs) are a severe, chronic, and recurrent complication of sickle-cell disease (SCD). There are no official recommendations for treatment. Recent Advances: Only a few studies with a high level of evidence have been conducted to evaluate treatment of SCLUs. However, several studies have been conducted with a high level of evidence to evaluate the efficacy of treatments in venous leg ulcers, and SCLUs could benefit from these treatments, especially when a venous incompetence or an edema is associated. Pathophysiology of SCLUs includes a vasculopathy related to chronic hemolysis and an endothelial dysfunction, which could be therapeutic approaches to SCLU treatment. Critical Issues: Therapeutic approaches to SCLUs can target SCD on the one hand and skin healing and associated aggravating factors on the other. A review of the literature found only case series and six randomized controlled trials; some offered encouraging results, but most had serious biases. Clinical trials specifically targeting SCLUs are difficult to realize because of the small number of affected patients, in comparison with patients with leg ulcers from other causes. Future Direction: Treating SCLUs remains a challenge. Data in the literature are currently insufficient to offer clear treatment guidelines because of several biases in controlled studies. New studies are under way to assess the efficacy of topical treatments and describe the microbiome of SCLUs. Prevention of SCLU recurrence should be assessed in future clinical trials because the high risk of recurrence is an unsolved critical issue.

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MME PATRICIA SENET

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Activité de recherche & publications

Publications académiques en France

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Top publications · les plus citées

Publications scientifiques (50) — classées par pathologie

Transversal27

Lupus5

Sclérodermie4

Biothérapies non-anti-TNF3

Case report / série3

Épidémiologie & registres3

Revue générale2

csDMARDs1

Essai clinique1

Génétique1

Gériatrie1

Maladie à IgG41

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