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Auteur de référence en rhumatologie
21 articles scientifiques publiés — un praticien à la pointe de la recherche
Délais de RDV courts dans la région
146.3 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CDS VYV NANCY
6 R DESILLES BP 70396, 54007 NANCY CEDEX
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Clinical rheumatology · 2008
The Journal of rheumatology · 2005
Lupus · 2008
Mycophenolate mofetil (MMF) with prednisolone has been associated with high remission rates when used as induction treatment for lupus nephritis. This prospective, multicentre, cohort study investigates the efficacy and safety of this regimen over 24 weeks in 213 Chinese patients with active lupus nephritis (Classes III, IV, V or combination). Baseline activity index (AI) was 6.91 ± 3.33 and chronicity index (CI) was 1.9 ± 1.2. The remission rate was 82.6% at 24 weeks (complete remission, 34.3%; partial remission, 48.4%). There were significant ( P < 0.01) improvements in kidney function shown by reductions in proteinuria, serum albumin, serum creatinine and creatinine clearance, as well as in systemic lupus erythematosus disease activity index (SLEDAI) scores. Independent risk factors influencing remission were pathological classification (including Class V and III or Class V and IV nephritis) and elevated serum creatinine at baseline (OR 2.967, 95% CI: 1.479–6.332, P = 0.001 and OR 1.007, 95% CI: 1.002–1.011, P = 0.001, respectively). Patients with concomitant membranous features on biopsy had a lower remission rate than those with Class III and IV nephritis (66.7% vs 87.3%, P = 0.002). Renal biopsy was repeated in 25 patients following treatment. There was a transition to less severe pathological morphologies in majority of subjects. Infections were monitored throughout treatment: eight patients (3.8%) experienced bacterial infections, whereas herpes zoster occurred in seven patients. Nine patients (4.2%) suffered from gastrointestinal upset, which resolved without discontinuation of MMF. One patient became leucopenic, whereas another died from active disease unrelated to kidney symptoms. MMF combined with prednisolone is an effective and well-tolerated induction treatment for patients with active lupus nephritis and for controlling SLE systemic activity.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
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H SM, McOnie RC, Bellefeuille SD, Tinga S, et al.
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BMJ case reports · 2023 · Case Reports
Scott S, Hakima L, Raff E
Radiology case reports · 2023 · Case Reports
Ezzahi M, Zaid E, Farid A, Allali S, et al.
African journal of infectious diseases · 2022 · Journal Article
Bouchra B, Wissal M, Amine C, Wail H, et al.
The Pan African medical journal · 2022 · Journal Article
Imane E, Ghizlane B, Reda JM, Hasna B, et al.
Cancer cytopathology · 2021 · Journal Article
Castrodad-Rodríguez CA, Lajara S, Khader SN, Colanta AB, et al.
Diagnostic microbiology and infectious disease · 2017 · Case Reports
Hakima N, Bidet P, Lopez M, Rioualen S, et al.
The open rheumatology journal · 2015 · Journal Article
Sun Y, Scannell BP, Honeycutt PR, Mauerhan DR, et al.
The open orthopaedics journal · 2015 · Journal Article
H N, A P S, S B, A U, et al.
The open orthopaedics journal · 2012 · Journal Article
M M, H G, S H, A J, et al.
African journal of reproductive health · 2023 · Journal Article
Hicham M, Abdellatif B, Nadia O, Hakima A
Annals of the rheumatic diseases · 2008 · Journal Article
Baron M, Sutton E, Hudson M, Thombs B, et al.
Clinical rheumatology · 2025 · Journal Article
A K, M EA, M H, H A, et al.
Clinical rheumatology · 2008 · Comparative Study
Santiago M, Baron M, Miyachi K, Fritzler MJ, et al.
Lupus · 2008 · Clinical Trial
F L, Y T, X P, L W, et al.
The Journal of rheumatology · 2005 · Journal Article
Pope JE, Lee P, Baron M, Dunne J, et al.
African journal of reproductive health · 2023 · Journal Article
Hicham M, Abdellatif B, Nadia O, Hakima A
The Journal of the Association of Physicians of India · 2022 · Journal Article
Jagdish GA, Va L, H KS
Archives of osteoporosis · 2025 · Journal Article
N BV, A MS, A DR, H SG, et al.
Archives of gerontology and geriatrics · 2021 · Journal Article
M R, M A, H B, M O