📇 Rhumatologue · TROISSEREUX · (60) · Libéral

MME SONIA ROCHARD-DROUARD

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Auteur de référence en rhumatologie
23 articles scientifiques publiés — un praticien à la pointe de la recherche
Référence presse grand public
Cité 1 fois dans les médias — pédagogie reconnue
Délais de RDV courts dans la région
73.1 rhumatos / 100 000 hab. — département bien doté

Rhumatologue

📍 TROISSEREUX (60)LibéralRPPS 10001808020

✨ Génération du profil synthétique IA en cours…

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26 BIS RUE DE LA GARE, 60112 TROISSEREUX
☎ 0344792102Activité de soin et de pharmacie

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Top publications · les plus citées

Impact of seasonal cycle on rheumatoid arthritis based on genetic and epigenetic mechanisms

Frontiers in immunology · 2025

📚 3 citations🔓 Open Access📄 PDF gratuit ↗

Lire l'abstract Crossref ↓

Rheumatoid arthritis is an autoimmune disease characterized by chronic inflammation and progressive joint destruction. Genetic and environmental risk factors contribute to the development of rheumatoid arthritis (RA). Among environmental factors, seasonal cycles are reported to impact the clinical phenotypes in RA, with rheumatic flares being aggravated during the winter season. Gaining insight into the seasonal effects on molecular drivers can be vital in resolving seasonal cycles in RA pathogenesis. To understand this phenomenon, genome-wide association study (GWAS) and candidate genes were reviewed to identify their role in susceptibility to RA. Subsequently, it was verified how many of these genes are modulated by seasonal influences. Furthermore, the role of epigenetic modifications, such as DNA methylation and non-coding RNAs, involved in RA pathogenesis and whether these epigenetic effects are also impacted by seasonal fluctuation were examined. Finally, it was investigated how these genetic and epigenetic mechanisms result in the breakdown of self-tolerance and the initiation of an autoimmune action. Upon overlapping the genetic and epigenetic observations influenced by seasonal cycles, it was evident that seasonal cycles do impact the genetic and epigenetic machinery, which possibly can explain the reasons for seasonal flares in RA pathogenesis. The evidence indicates that genetic and epigenetic mechanisms are driven by climatic variation and that the timing and duration of the aberrant expression of immune response genes will drive the autoantibodies to develop seasonal flares of RA.

The effectiveness of radial extracorporeal shock wave therapy (rESWT) in plantar fasciitis: a 12 months randomised controlled trial in a Tunisian rehabilitation department

BMC musculoskeletal disorders · 2025

📚 2 citations🩺 Clinique🔓 Open Access📄 PDF gratuit ↗

Integrating neurological expertise into One Health strategies for pediatric neurocysticercosis-associated epilepsy control in Sub-Saharan Africa: a narrative review

One health outlook · 2025

📚 2 citations🔓 Open Access📄 PDF gratuit ↗

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MME SONIA ROCHARD-DROUARD

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Articles de presse (1)

Top publications · les plus citées

Publications scientifiques (23) — classées par pathologie

Essai clinique4

Transversal4

Case report / série3

Pharmacovigilance3

Revue générale3

Lupus2

Pédiatrie2

Vraie vie / RWE2

Économie santé1

Épidémiologie & registres1

Génétique1

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