📇 Rhumatologue · PARIS · (75) · Hospitalier

MME DANIELE RANOUX

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5 raisons identifiées

Plateau technique de référence
Centre hospitalier universitaire (CHU) — équipements et expertise pointus pour les cas complexes
Praticien-chercheur
15 articles scientifiques publiés — formation continue solide
Référence presse grand public
Cité 1 fois dans les médias — pédagogie reconnue
Disponibilité géographique
3 lieux d'exercice — choisissez celui qui vous arrange
Délais de RDV courts dans la région
336.2 rhumatos / 100 000 hab. — département bien doté

Rhumatologue

📍 PARIS (75)HospitalierRPPS 10000485416

📊 Reconnaissance scientifique : 17/100📝 47 articles publiés🇫🇷 Publications académiques françaises (8)

✨ Génération du profil synthétique IA en cours…

Activité de recherche & publications

Indicateurs publics agrégés sur 250 M+ d'œuvres scientifiques (OpenAlex, PubMed). Traduits ici en langage patient.

Influence scientifique

Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.

Top publications · les plus citées

Botulinum toxin type A induces direct analgesic effects in chronic neuropathic pain

Annals of neurology · 2008

📚 301 citations🎯 RCR 10.61Top 2% NIH🩺 Clinique

Lire l'abstract Crossref ↓

Abstract Objective Botulinum toxin type A (BTX‐A) has been reported to have analgesic effects independent of its action on muscle tone, possibly by acting on neurogenic inflammation. Such a mechanism may be involved in peripheral neuropathic pain. Methods A possible direct analgesic effect of BTX‐A pain processing was investigated in 29 patients with focal painful neuropathies and mechanical allodynia using a randomized, double‐blind, placebo‐controlled design. Patients received a one‐time intradermal administration of BTX‐A (20–190 units) into the painful area. Outcome measures, evaluated at baseline, then at 4, 12, and 24 weeks, included average spontaneous pain intensity, quantified testing of thermal and mechanical perception and pain, allodynia to brushing (area, intensity), neuropathic symptoms, clinical global impression, and quality of life. Results BTX‐A treatment, relative to placebo, was associated with persistent effects on spontaneous pain intensity from 2 weeks after the injection to 14 weeks. These effects correlated with the preservation of thermal sensation at baseline ( p < 0.05). BTX also improved allodynia to brush and decreased pain thresholds to cold, without affecting perception thresholds. There were sustained improvements in the proportion of responders (number needed to treat for 50% pain relief: 3.03 at 12 weeks), neuropathic symptoms, and general activity. Most patients reported pain during the injections, but there were no further local or systemic side effects. Interpretation These results indicate for the first time that BTX‐A may induce direct analgesic effects in patients with chronic neuropathic pain independent of its effects on muscle tone and suggest novel indications for BTX‐A in analgesia. Ann Neurol 2008

Safety and efficacy of repeated injections of botulinum toxin A in peripheral neuropathic pain (BOTNEP): a randomised, double-blind, placebo-controlled trial

The Lancet. Neurology · 2016

📚 170 citations🎯 RCR 8.50Top 3% NIH🩺 Clinique

A systematic review of studies on anatomical position of electrode contacts used for chronic subthalamic stimulation in Parkinson's disease

Acta neurochirurgica · 2013

📚 75 citations🎯 RCR 2.71Top 18% NIH

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MME DANIELE RANOUX

Pourquoi vous devez consulter ce praticien

Activité de recherche & publications

Publications académiques en France

Lieux de consultation(3)

Tarifs & secteur de conventionnement

Prendre rendez-vous & contact

Articles de presse (1)

Top publications · les plus citées

Publications scientifiques (15) — classées par pathologie

Transversal8

Essai clinique4

Revue / méta-analyse2

Case report / série1

Épidémiologie & registres1

Pharmacovigilance1

Revue générale1

Santé mentale / fatigue1

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