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Délais de RDV courts dans la région
89.2 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CABINET DU DR FADI RAAD
CLINIQUE ESQUIROL ST HILAIRE 1 RUE DU DR ET MME DELMAS, 47000 AGEN
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Ocular immunology and inflammation · 2025
Rheumatology (Oxford, England) · 2026
Abstract Objectives Treatment of GCA still requires substantial exposure to glucocorticoids (GCs), which are associated with significant toxicity. This study compares the efficacy and safety of the GC-only standard of care (SOC) with a regimen combining intravenous methylprednisolone (IVMP) pulses, MTX and lower doses of prednisone, in newly diagnosed patients with GCA. Methods A usual clinical practice study was conducted in three Spanish academic hospitals. One hundred and fifty-one patients diagnosed with GCA were treated with SOC prednisone (40–60 mg/d) or with IVMP (125–500 mg/d ×3) followed by lower-dose prednisone (≤30 mg/d) and MTX (IVMP/MTX), with a follow-up of 2 years. A propensity score was used to adjust for baseline differences in the multivariate analyses. Results Seventy-nine (52.3%) patients received SOC prednisone and 72 (47.7%) IVMP/MTX. The clinical characteristics at baseline were similar in both the groups. Hundred percent patients achieved remission after a median time of 4 weeks, without differences between the groups. Relapse rates were also similar. Patients receiving IVMP/MTX had significantly lower cumulative GC doses and reached prednisone ≤5 mg/d faster than SOC patients (mean 13.8 vs 56.5 weeks; P < 0.001). Patients in the IVMP/MTX group were less likely to suffer any GC-related adverse effect (adjusted OR 0.35, 95% CI 0.14–0.85; P = 0.021). Conclusions The combination IVMP/MTX with lower-dose prednisone is as effective as the SOC in inducing remission and preventing relapses in GCA. The IVMP/MTX scheme significantly reduces GC exposure and GC-associated adverse effects. IVMP/MTX could be a potential GC-sparing strategy, especially in patients with GCA at higher risk of GC toxicity.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Ocular immunology and inflammation · 2025 · Journal Article
Raad F, Luque P, García Ledo S, Alda Lozano A, et al.
Rheumatology (Oxford, England) · 2026 · Journal Article
Soto-Peleteiro A, Hernández-Rodríguez J, Raad F, de Miguel B, et al.
Rheumatology (Oxford, England) · 2026 · Journal Article
Soto-Peleteiro A, Hernández-Rodríguez J, Raad F, de Miguel B, et al.
European journal of internal medicine · 2026 · Journal Article
Pelegrín L, Araújo O, Espinosa G, Rodríguez-Pintó I, et al.