📇 Rhumatologue · CAEN CEDEX 9 · (14) · Hospitalier
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5 raisons identifiées
Plateau technique de référence
Centre hospitalier universitaire (CHU) — équipements et expertise pointus pour les cas complexes
Encadrant universitaire
Forme la prochaine génération de rhumatologues (1 thèse dirigée)
Praticien-chercheur
12 articles scientifiques publiés — formation continue solide
Expérience confirmée
27 ans d'exercice en rhumatologie — recul clinique solide
Délais de RDV courts dans la région
150.8 rhumatos / 100 000 hab. — département bien doté
27ans d'exercice (thèse 1999)
✨ Génération du profil synthétique IA en cours…
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
Metabolisme energetique et remaniements membranaires : - effets de la carence alimentaire en acides gras polyinsatures. - consequences de l'ingestion chronique d'ethanol
Direction : Xavier Leverve
Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.
Source theses.fr — signal de direction d'équipe / statut PU-PH (à confirmer via le site universitaire).
Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.
Impact of timing of access to endoscopic drainage and social determinants of health on the prognosis of patients with periampullary cancer diagnosed through jaundice: a multicenter retrospective study
2026ArticleTherapeutic Advances in Gastroenterology
Assessment of the Risk of Musculoskeletal Disorders Associated with the Practice of Endoscopic Retrograde Cholangiopancreatography (ERCP)
2025ArticleDigestive Diseases and Sciences
Early prediction of mortality in acute cholangitis: Elaboration of a new simple prognostic score
2025ArticleHepatobiliary and Pancreatic Diseases International
Prognostic value of the measurement at admission of the inferior vena cava in acute pancreatitis
2025ArticleJournal of Hepato-Biliary-Pancreatic Sciences
Guselkumab in patients with moderately to severely active ulcerative colitis (QUASAR): phase 3 double-blind, randomised, placebo-controlled induction and maintenance studies
2025ArticleThe Lancet
Effects of repetitive transcranial magnetic stimulation of the right inferior parietal lobe on the body image perception in anorexia nervosa: A pilot randomized controlled study
2024ArticleBrain and Behavior
Functional sequelae after pancreatic resection for cancer
2023ArticleJournal of Visceral Surgery
Comment nourrir l’insuffisant hépatique ? Réflexions sur les recommandations européennes à partir de situations cliniques
2023ArticleNutrition Clinique et Métabolisme
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
CHU CAEN
AV COTE DE NACRE, 14033 CAEN CEDEX 9
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Hepatology (Baltimore, Md.) · 2004
Tumor necrosis factor-α (TNF-α) may contribute to the progression of acute alcoholic hepatitis (AAH). The aim of this study was to evaluate the efficacy of an association of infliximab and prednisolone at reducing the 2-month mortality rate among patients with severe AAH. Patients with severe AAH (Maddrey score ≥32) were randomly assigned to group A receiving intravenous infusions of infliximab (10 mg/kg) in weeks 0, 2, and 4; or group B receiving a placebo at the same times. All patients received prednisolone (40 mg/day) for 28 days. Blood neutrophil functional capacities were monitored over 28 days. After randomization of 36 patients, seven patients from group A and three from group B died within 2 months. The probability of being dead at 2 months was higher (not significant [NS]) in group A (39% ± 11%) than in group B (18% ± 9%). The study was stopped by the follow-up committee and the sponsor (Assistance Publique-Hôpitaux de Paris). The frequency of severe infections within 2 months was higher in group A than in group B (P < .002). This difference was potentially related to a significantly lower ex vivo stimulation capacity of neutrophils. There were no differences between the two groups in terms of Maddrey scores at any time point. In conclusion, three infusions of 10 mg/kg of infliximab in association with prednisolone may be harmful in patients with severe AAH because of the high prevalence of severe infections. (Hepatology 2004;39:1390-1397.)
The New England journal of medicine · 2011
JPEN. Journal of parenteral and enteral nutrition · 2006
Background: Jejunal nutrition is recommended during acute pancreatitis. The use of semi‐elemental formulas presents several theoretical advantages over polymeric formulas, but their clinical value has been poorly documented. Our aim was to evaluate in patients with acute pancreatitis the effect of enteral nutrition by a semi‐elemental formula compared with a polymeric formula. Methods: A randomized prospective pilot study, stratified according to severity, was performed in 30 consecutive patients with acute pancreatitis requiring jejunal nutrition. The semi‐elemental group received 35 kcal/kg/d of Peptamen (n = 15), and the polymeric group received the same quantity of Sondalis‐Iso (n = 15). Tolerance was evaluated after 7 days of enteral nutrition (D7) on visual analog scale (VAS), stool frequency, and 24‐hour steatorrhea/creatorrhea. Outcome was evaluated by weight loss, length of hospital stay, and infection rate. Results: Results were calculated as mean ± SEM, t‐test, or χ2. Patients of the 2 groups were comparable in terms of age, gender, and severity. Tolerance was good in both groups (semi‐elemental vs polymeric: VAS, 7.4 ± 0.6 vs 7.1 ± 0.6, not significant (NS); number of stools per 24 hours, 1.7 ± 0.4 vs 1.8 ± 0.4, NS). Steatorrhea and creatorrhea were lower than normal in both groups. In semi‐elemental group, the length of hospital stay was shorter (23 ± 2 vs 27 ± 1, p = .006) and weight loss was less marked (1 ± 1 vs 2 ± 0, p = .01). One patient in semi‐elemental group and 3 patients in polymeric group developed an infection (NS). Conclusions: Semi‐elemental and polymeric nutrition are very well tolerated in patients with acute pancreatitis. Nutrition with a semi‐elemental formula supports the hypothesis of a more favorable clinical course than nutrition with a polymeric formula, but this conclusion needs to be established in larger adequately powered clinical trials.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2023 · Journal Article
Chaigneau T, Morello R, Vannier E, Musikas M, et al.
Nutrition (Burbank, Los Angeles County, Calif.) · 2021 · Letter
Piquet MA, Dupont B
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2015 · Journal Article
Dupont B, Delvincourt M, Koné M, du Cheyron D, et al.
The New England journal of medicine · 2011 · Comparative Study
Nguyen-Khac E, Thevenot T, Piquet MA, Benferhat S, et al.
Molecular nutrition & food research · 2008 · Journal Article
Dupont B, Dupont C, Justum AM, Piquet MA, et al.
Gastroenterologie clinique et biologique · 2006 · English Abstract
Piquet MA, Gloro R, Justum AM, Reimund JM
Current opinion in clinical nutrition and metabolic care · 2002 · Journal Article
Bertrand PC, Piquet MA, Bordier I, Monnier P, et al.
Brain and behavior · 2024 · Journal Article
Chastan N, Achamrah N, Etard O, Nathou C, et al.
Nutrition (Burbank, Los Angeles County, Calif.) · 2016 · Letter
Dupont B, Piquet MA
JPEN. Journal of parenteral and enteral nutrition · 2006 · Comparative Study
Tiengou LE, Gloro R, Pouzoulet J, Bouhier K, et al.
Hepatology (Baltimore, Md.) · 2004 · Clinical Trial
Naveau S, Chollet-Martin S, Dharancy S, Mathurin P, et al.
Health equity · 2022 · Journal Article
Dupont B, Dejardin O, Bouvier V, Piquet MA, et al.
Health equity · 2022 · Journal Article
Dupont B, Dejardin O, Bouvier V, Piquet MA, et al.