📇 Rhumatologue · LEUVILLE SUR ORGE · (91) · Libéral

MME Margaretha ORYE-CORLOUER

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Auteur de référence en rhumatologie
41 articles scientifiques publiés — un praticien à la pointe de la recherche
Délais de RDV courts dans la région
73.2 rhumatos / 100 000 hab. — département bien doté

Rhumatologue

📍 LEUVILLE SUR ORGE (91)LibéralRPPS 10000895440

✨ Génération du profil synthétique IA en cours…

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Top publications · les plus citées

School-based mental health promotion: A global policy review

Frontiers in psychiatry · 2023

📚 22 citations🎯 RCR 5.01Top 8% NIH🔓 Open Access📄 PDF gratuit ↗

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ObjectivesSchools are increasingly recognized as important settings for mental health promotion, but it is unclear what actions schools should prioritize to promote student mental health and wellbeing. We undertook a policy review of global school-based mental health promotion policy documents from United Nations (UN) agencies to understand the frameworks they use and the actions they recommend for schools.MethodsWe searched for guidelines and manuals from UN agencies through the World Health Organization (WHO) library, the National Library of Australia and Google Scholar, from 2000 to 2021, using various combinations of search terms (e.g., mental health, wellbeing, psychosocial, health, school, framework, manual, and guidelines). Textual data synthesis was undertaken.ResultsSixteen documents met inclusion criteria. UN policy documents commonly recommended a comprehensive school-health framework aimed at integrating actions to prevent, promote, and support mental health problems within the school community. The primary role of schools was framed around building enabling contexts for mental health and wellbeing. Terminology was relatively inconsistent across different guidelines and manuals, particularly around how comprehensive school health was conceptualized, which included aspects of scope, focus, and approach.ConclusionUnited Nations policy documents are oriented toward comprehensive school-health frameworks for student mental health and wellbeing that include mental health within wider health-promoting approaches. There are expectations that schools have the capabilities to deliver actions to prevent, promote and support mental health problems.ImplicationEffective implementation of school-based mental health promotion requires investments that facilitate specific actions from governments, schools, families, and communities.

Phase IV postmarketing surveillance study shows continued efficacy and safety of Stempeucel in patients with critical limb ischemia due to Buerger's disease

Stem cells translational medicine · 2021

📚 17 citations🎯 RCR 1.35🩺 Clinique🔓 Open Access📄 PDF gratuit ↗

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Abstract Buerger's disease or thromboangiitis obliterans is a type of obstructive vascular diseases categorized as vasculitis and usually present in 95% of young smoker men. The main pathogenetic mechanism is interplay between immune system and inflammation. Earlier our phase II study has shown that Stempeucel is safe when injected at 2 million cells/kg body weight by virtue of its anti-inflammatory, immunomodulatory, and angiogenetic properties. The present study was conducted to further assess the safety and efficacy of Stempeucel in critical limb ischemia due to Buerger's disease after obtaining approval from Indian FDA based on the data generated in the phase II study. This is an open label, multicenteric phase IV PMS study conducted across India with experienced vascular surgeons. Fifty patients of critical limb ischemia due to Buerger's disease with Rutherford III-5 or III-6 were included in the study and each individual received a dose of 2 million cells/kg body weight of Stempeucel in the calf muscles and around the ulcer. These patients were evaluated over 12 months from drug administration. The present study showed the continued long term efficacy over a period of 12 months follow up in these patients corroborating the result obtained in the previous phase II studies. There was significant improvement in rest pain, ankle systolic pressure, and ankle brachial pressure index with accelerated ulcer healing. In conclusion, the present study shows that the intramuscular administration of Stempeucel continues to be safe, tolerable, and effective alternative treatment in patients with Buerger's disease.

An Evaluation of Efficacy and Safety of Tofacitinib, A JAK Inhibitor in the Management of Hospitalized Patients with Mild to Moderate COVID-19 - An Open-Label Randomized Controlled Study

The Journal of the Association of Physicians of India · 2022

📚 16 citations🎯 RCR 1.11🩺 Clinique

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MME Margaretha ORYE-CORLOUER

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Top publications · les plus citées

Publications scientifiques (41) — classées par pathologie

Transversal10

Case report / série4

Pédiatrie3

Revue générale3

Santé mentale / fatigue3

Arthrite juvénile2

Essai clinique2

Vascularites des gros vaisseaux2

Vraie vie / RWE2

csDMARDs1

Économie santé1

Épidémiologie & registres1

Génétique1

JAK inhibiteurs1

Lombalgie1

Lupus1

Maladie à IgG41

Pharmacovigilance1

Qualité de vie / PROMs1

Recommandations1

Revue / méta-analyse1

Sjögren1

Tendinopathies & SCC1

Vascularites1

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