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2 raisons identifiées
Auteur de référence en rhumatologie
27 articles scientifiques publiés — un praticien à la pointe de la recherche
Référence presse grand public
Cité 5 fois dans les médias — pédagogie reconnue
✨ Génération du profil synthétique IA en cours…
Indicateurs publics agrégés sur 250 M+ d'œuvres scientifiques (OpenAlex, PubMed). Traduits ici en langage patient.
Influence scientifique
4
4 articles ont été cités au moins 4fois par d'autres chercheurs — preuve que ses travaux sont repris par la communauté médicale.
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
h-index
Total citations reçues
185
Nombre de fois où d'autres équipes ont mentionné ses publications dans leurs propres travaux.
Publications totales
19
Articles, revues et chapitres référencés dans les bases académiques internationales.
Articles influents
3
Publications ayant marqué leur domaine — chacune citée au moins 10 fois par d'autres chercheurs.
i10-index
Thématiques principales
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.
Flexible thermoelectric device based on TiS2(HA)x n-type nanocomposite printed on paper
2019ArticleOrganic Electronics
Organic thermoelectric devices based on a stable n-type nanocomposite printed on paper
2018ArticleSustainable Energy & Fuels
Générateur thermoélectrique flexible imprimé sur papier à base de matériaux organiques et hybrides
2017CongrèsScience et Tecnologie des Systèmes Pi-Conjugués
N-type Poly(3,4-ethylene dioxythiophene)/V2O5 hybrid material obtained by intercalation for flexible thermoelectric devices
2016CongrèsInternational Conference on Organic and Hybrid Thermoelectrics (ICOT) 2016
Recherche sur les implications sociales et légales des nanomatériaux. Point de vue d'un industriel
2014CongrèsNanomines LES JOURNÉES INDUSTRIELLES « NANOMATÉRIAUX »
Use of electrochemical techniques to study the corrosion of metals in model fluoride melts
2013ArticleJournal of Nuclear Materials
Electrochemical study of the corrosion of metals in molten fluorides
2008CongrèsHigh-Temperature Corrosion and Protection of Materials Conference
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).
📰 Le Dauphiné Libéré · 31/03/2021
<a href="https://news.google.com/rss/articles/CBMisAFBVV95cUxQbFFKSHBmZ3cxcHJ4bHVYQjJheGQ1b0VvXzN4dUNFd0tqY0FYRkN5c2hLb3d6NW9Bd2t0TndtdFFabW5iTElvbmxpaFEyUmI0UXAzeW1tTGQ3c09wMk1wWkdCSlFtT0hIdmhxR3kteGxkcENjYW5LTU5PNEhfdzAxSjhWVHpBYzNuUEppWUpMNUZVMUU3QTcySjYtd3k0OF9vcGtnMlNaQ3gtNTduVF85NQ?oc=5" targe
📰 Le Republicain Lorrain · 26/03/2017
<a href="https://news.google.com/rss/articles/CBMiuAFBVV95cUxNeUszMmVmaE9YbTBQdi1VSnVFX3ZKYTdVbkFlQlhsVHQzSDhVNHNaZjhMWXZBTlRURl8xUm1FV0NvdDI1STdtWksydkVRUm5KQTNhWi1HaERtY2FHSF9rbWhDWXJDamtNejN4M25rcnRnOG85enA2WWREYUhNRnFDNUhWQ2NPaTM2T3hibUc0M2hMSUhrX2l3VWc5eEs0Z0tnZExWaUFwa1RGVDFTakg0WFY5UU1zay1s?o
📰 Actu.fr · 10/05/2018
<a href="https://news.google.com/rss/articles/CBMizAFBVV95cUxOaGJ0Y2NtTzlKTTRKSGFwcXNRTnpfLVo2dXROQmJEMElwOW5lX0p6VklQcHlad0YzWWJyWDEtS3R0b1MzRTZFdWduUGxfVG1tT20zQ0Q5LWVqeDU2Uk1XNG1icnVFNE9vZnlJckJTdm5Bb2NZQnJNaEtrRWxQSTlIS2RYZFpFX3NCSHFqcEFVMnNlVkVaX1BoaFUtcnh3SDB5cGF0bkNIcF9fQVpVV2d0Z3pRekkyZWhhQX
📰 Le Dauphiné Libéré · 03/12/2020
<a href="https://news.google.com/rss/articles/CBMisAFBVV95cUxOODMyVndFQXpUQ0lXWnZoMHRfc0dqOGZpYjUtWDBuX1NQZDNidUdFcnhxMHUwbV9jWU9TemhBdFdmX29YbDFSRVRjRElvMllLdl95eUh0aU9DWTltdEQ3cWxqaXEzbi1qWXg4YVhqWEljcElocExRanFJR25GWHBqZlJxanQ5WEV4YzVmTzlmNTdMalN5YzJfanRBbVhkcjNSTnZCR0FxOE95bEFzU3dqXw?oc=5" targe
📰 Le Republicain Lorrain · 21/11/2024
<a href="https://news.google.com/rss/articles/CBMi3AFBVV95cUxPakdVU09kN3NqQjdYR0sxVEx5N3QwS1BVS3Q2bnRvQ1h1TUhQczhIWmhNOTg0Z0IxWWxDYV8teVEycWdRU3J4czBUdVdMbmRTVkRVSVE0bnhqaGNyQVAwNV9wbnFXZ0hxVlluWXh0aHlJa3JzZHM2ZU9fVHlYblZwVWhDb0NPVkpqTmZTQ0RYT0o2cWQzYng3QWpNXzBmZ203Ym5YbE82bThjS0tGbk1rVjB4LWdoT1NkeT
Scientific reports · 2017
AbstractMesenchymal stem or stromal cells (MSCs) exert chondroprotective effects in preclinical models of osteoarthritis (OA). Most of their therapeutic effects are mediated via soluble mediators, which can be conveyed within extracellular vesicles (EVs). The objective of the study was to compare the respective role of exosomes (Exos) or microvesicles/microparticles (MPs) in OA. MPs and Exos were isolated from bone marrow murine BM-MSCs through differential centrifugation. Effect of MPs or Exos was evaluated on OA-like murine chondrocytes and chondroprotection was quantified by RT-qPCR. In OA-like chondrocytes, BM-MSC-derived MPs and Exos could reinduce the expression of chondrocyte markers (type II collagen, aggrecan) while inhibiting catabolic (MMP-13, ADAMTS5) and inflammatory (iNOS) markers. Exos and MPs were also shown to protect chondrocytes from apoptosis and to inhibit macrophage activation. In vivo, Exos or MPs were injected in the collagenase-induced OA (CIOA) model and histomorphometric analyses of joints were performed by µCT and confocal laser microscopy. BM-MSCs, MPs and Exos equally protected mice from joint damage. In conclusion, MPs and Exos exerted similar chondroprotective and anti-inflammatory function in vitro and protected mice from developing OA in vivo, suggesting that either Exos or MPs reproduced the main therapeutic effect of BM-MSCs.
Stem cells translational medicine · 2016
Abstract Osteoarthritis (OA) is the most widespread musculoskeletal disorder in adults. It leads to cartilage damage associated with subchondral bone changes and synovial inflammation, causing pain and disability. The present study aimed at evaluating the safety of a dose-escalation protocol of intra-articular injected adipose-derived stromal cells (ASCs) in patients with knee OA, as well as clinical efficacy as secondary endpoint. A bicentric, uncontrolled, open phase I clinical trial was conducted in France and Germany with regulatory agency approval for ASC expansion procedure in both countries. From April 2012 to December 2013, 18 consecutive patients with symptomatic and severe knee OA were treated with a single intra-articular injection of autologous ASCs. The study design consisted of three consecutive cohorts (six patients each) with dose escalation: low dose (2 × 106 cells), medium dose (10 × 106), and high dose (50 × 106). The primary outcome parameter was safety evaluated by recording adverse events throughout the trial, and secondary parameters were pain and function subscales of the Western Ontario and McMaster Universities Arthritis Index. After 6 months of follow-up, the procedure was found to be safe, and no serious adverse events were reported. Four patients experienced transient knee joint pain and swelling after local injection. Interestingly, patients treated with low-dose ASCs experienced significant improvements in pain levels and function compared with baseline. Our data suggest that the intra-articular injection of ASCs is a safe therapeutic alternative to treat severe knee OA patients. A placebo-controlled double-blind phase IIb study is being initiated to assess clinical and structural efficacy. Significance Although this phase I study included a limited number of patients without a placebo arm, it showed that local injection of autologous adipose-derived stem cells was safe and well tolerated in patients with knee osteoarthritis. This study also provides encouraging preliminary evidence of efficacy. Larger and controlled long-term studies are now mandatory to confirm whether this new strategy of cell therapy can improve pain and induce structural benefit in osteoarthritis.
Biomaterials · 2016
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Theranostics · 2025 · Journal Article
Said M, Tavakoli C, Dumot C, Toupet K, et al.
Osteoarthritis and cartilage · 2024 · Journal Article
Théron A, Maumus M, Biron-Andreani C, Sirvent N, et al.
Frontiers in bioengineering and biotechnology · 2023 · Journal Article
Vignon C, Hilpert M, Toupet K, Goubaud A, et al.
Scientific reports · 2023 · Journal Article
Toupet K, Jorgensen C, Noël D
Respiratory medicine and research · 2021 · Journal Article
Noel-Savina E, Viatgé T, Faviez G, Lepage B, et al.
Clinical and experimental rheumatology · 2021 · Journal Article
Mariotte A, Bernardi L, Macquin C, DeCauwer A, et al.
Advanced drug delivery reviews · 2021 · Journal Article
Boulestreau J, Maumus M, Jorgensen C, Noël D
Frontiers in cell and developmental biology · 2021 · Journal Article
Tejedor G, Contreras-Lopez R, Barthelaix A, Ruiz M, et al.
Gels (Basel, Switzerland) · 2021 · Journal Article
Valot L, Maumus M, Brunel L, Martinez J, et al.
Journal of autoimmunity · 2021 · Journal Article
Bodard Q, Langlois V, Guilpain P, Le Quellec A, et al.
Osteoarthritis and cartilage · 2020 · Journal Article
Maumus M, Noël D, Ea HK, Moulin D, et al.
Osteoarthritis and cartilage · 2019 · Journal Article
Ruiz M, Maumus M, Fonteneau G, Pers YM, et al.
Medecine sciences : M/S · 2018 · Journal Article
Maumus M, Pers YM, Ruiz M, Jorgensen C, et al.
Aging · 2018 · Journal Article
Chuchana P, Mausset-Bonnefont AL, Mathieu M, Espinoza F, et al.
Frontiers in immunology · 2017 · Journal Article
Maumus M, Manferdini C, Toupet K, Chuchana P, et al.
Scientific reports · 2017 · Journal Article
Cosenza S, Ruiz M, Toupet K, Jorgensen C, et al.
Revue des maladies respiratoires · 2017 · Case Reports
Mhanna L, Noel-Savina E, Pontier S, Jaffro M, et al.
Frontiers in immunology · 2016 · Journal Article
Maumus M, Roussignol G, Toupet K, Penarier G, et al.
Stem cells translational medicine · 2016 · Clinical Trial, Phase I
Pers YM, Rackwitz L, Ferreira R, Pullig O, et al.
Biomaterials · 2016 · Journal Article
Morille M, Toupet K, Montero-Menei CN, Jorgensen C, et al.
Annals of medicine · 2022 · Journal Article
Goulabchand R, Makinson A, Morel J, Witkowski-Durand-Viel P, et al.
Journal of clinical medicine · 2022 · Journal Article
Goulabchand R, Gabelle A, Ayrignac X, Malafaye N, et al.
Autoimmunity reviews · 2021 · Journal Article
Goulabchand R, Malafaye N, Jacot W, Witkowski Durand Viel P, et al.
Stem cell research · 2021 · Journal Article
Pichard L, Brondello JM, Becker F, Desprat R, et al.
Stem cell research · 2020 · Journal Article
Pichard L, Brondelo JM, Becker F, Desprat R, et al.
BMC cardiovascular disorders · 2020 · Case Reports
Mansour MJ, Bénic C, Didier R, Noel A, et al.
Clinical practice in pediatric psychology · 2024 · Journal Article
Nelson CI, Noel D, Caes L, McCabe KM, et al.
Clinical practice in pediatric psychology · 2024 · Journal Article
Nelson CI, Noel D, Caes L, McCabe KM, et al.
Clinical practice in pediatric psychology · 2024 · Journal Article
Nelson CI, Noel D, Caes L, McCabe KM, et al.