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MME MARIA NIETO-DUTRIEUX

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Auteur de référence en rhumatologie
29 articles scientifiques publiés — un praticien à la pointe de la recherche

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Top publications · les plus citées

Sleep quality and disturbance during the COVID-19 pandemic among people with HIV globally: associations with social determinants of health

AIDS (London, England) · 2026

📚 1 citations🩺 Clinique

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Objective: To examine the impact of coronavirus disease 2019 (COVID-19) on sleep quality and sleep disturbance and explore the relationship between social determinants of health, clinical factors, and sleep quality and sleep disturbance in a global sample of people with HIV (PWH). Design: Cross-sectional prospective international observational study to examine the social, mental, and physical health impacts of COVID-19 on sleep health of PWH. Methods: A modified version of the Adolescent Trials Network (ATN) COVID Questionnaire was utilized to collect sleep quality and social determinant of health data in adult PWH. Sleep disturbance was determined from a single item from the Fear of COVID-19 Scale. A series of logistic regressions were conducted to explore the relationship of social determinants of health with decreased sleep quality and disturbance. Results: A sample of 1601 PWH from four continents (Africa, Asia, North America, and South America) were included with 61% male, a mean age of 44.18 (±13.67) and living with HIV for an average of 12.8 years (±9.6). During the COVID-19 pandemic, 26.8% of participants experienced decreased sleep quality and 27.1% experienced sleep disturbance with the highest prevalence among participants residing in Africa. Individuals with decreased access to resources (food and money) were 0.23 times more likely to have decreased sleep quality compared to individuals with increased access to resources ( P < 0.001). PWH with no education were 2.83 times more likely to experience sleep disturbance than those with at least some postsecondary education ( P < 0.001). Conclusions: Our findings demonstrate the COVID-19 pandemic significantly impacted sleep quality and disturbance in PWH.

Adjuvant VaccInation After Conization for the Treatment for CervicAL Dysplasia

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2026

📚 1 citations

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This study aimed to evaluate the role of adjuvant HPV vaccination in women undergoing conization for cervical intraepithelial neoplasia. This prospective study assessed factors influencing recurrence in patients undergoing conization for high-grade cervical dysplasia. After conization, patients were counseled on the potential benefits of vaccination. We compared outcomes between two groups: women who underwent conization with adjuvant human papillomavirus (HPV) vaccination and observation versus conization with observation only. Data from 281 patients were analyzed, comprising 168 (59.8%) patients in the conization-only group and 113 (40.2%) patients in the conization-plus vaccination group. Vaccinated patients were younger than nonvaccinated patients (38 vs. 45 years, P < 0.001). Positive surgical margins were more frequently observed in the vaccinated group compared with the nonvaccinated group (9.7 vs. 3.6%; P = 0.038). Median follow-up was shorter in the vaccinated group, although this difference was not statistically significant (24.9 vs. 27.8 months; P = 0.395). The risk of developing HPV-related lesions was similar between the vaccinated and nonvaccinated groups ( P = 0.594, log-rank test). Likewise, the need for reconization did not differ significantly between the groups ( P = 0.593, log-rank test). Multivariate analysis showed no significant impact of HPV vaccination on postoperative outcomes [hazard ratio (HR): 0.50, 95% confidence interval (CI): 0.15–1.68) for any lesion; HR: 0.90, 95% CI: 0.47–1.73 for reconization]. This study indicates that adjuvant HPV vaccination does not significantly affect short-term outcomes in women undergoing conization for cervical dysplasia. Ongoing randomized trials will provide more robust evidence to clarify the role of adjuvant vaccination in this setting.

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MME MARIA NIETO-DUTRIEUX

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Publications scientifiques (29) — classées par pathologie

Transversal14

Revue générale5

Pédiatrie3

Revue / méta-analyse3

Essai clinique2

Santé mentale / fatigue2

Case report / série1

Économie santé1

IRM ostéo-articulaire1

Lupus1

Vraie vie / RWE1

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