📇 Rhumatologue ·
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2 raisons identifiées
Auteur de référence en rhumatologie
34 articles scientifiques publiés — un praticien à la pointe de la recherche
Référence presse grand public
Cité 1 fois dans les médias — pédagogie reconnue
✨ Génération du profil synthétique IA en cours…
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📰 Vietnam.vn · 07/07/2025
<a href="https://news.google.com/rss/articles/CBMikwFBVV95cUxOS09ZcjJoVEpuYWJ2NXAxME5SY3FieDA5YmpWS1VsRGg5NGNxUUtYTklmRkFvTWhDQTJZQjZoSFdoemVfREhfdjg0dW05eWtyb1BnbWh1TGdRZzJZeDl3WktDanZQU3ZPTWhFVU1URFNSeUFiTllJbFdHWTBlSndUSVZDYTJfQ3FXLWVrTkhONk9nczg?oc=5" target="_blank">L'équipe vietnamienne des mo
Annals of the rheumatic diseases · 2021
International journal of molecular sciences · 2022
Rheumatoid arthritis (RA), an autoimmune disease, is characterized by chronic joint inflammation and pain. We previously found that the deletion of T-cell death-associated gene 8 (TDAG8) significantly reduces disease severity and pain in RA mice. Whether it is by modulating gut microbiota remains unclear. In this study, 64 intestinal samples of feces, cecal content, and cecal mucus from the complete Freund’s adjuvant-induced arthritis mouse models were compared. The α- and β-diversity indices of the microbiome were significantly lower in RA mice. Cecal mucus showed a higher ratio of Firmicutes to Bacteroidetes in RA than healthy mice, suggesting the ratio could serve as an RA indicator. Four core genera, Eubacterium_Ventriosum, Alloprevotella, Rikenella, and Treponema, were reduced in content in both feces and mucus RA samples, and could serve microbial markers representing RA progression. TDAG8 deficiency decreased the abundance of proinflammation-related Eubacterium_Xylanophilum, Clostridia, Ruminococcus, Paraprevotella, and Rikenellaceae, which reduced local mucosal inflammation to relieve RA disease severity and pain. The pharmacological block of the TDAG8 function by a salicylanilide derivative partly restored the RA microbiome to a healthy composition. These findings provide a further understanding of specific bacteria interactions with host gut mucus in the RA model. The modulation by TDAG8 on particular bacteria can facilitate microbiota-based therapy.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Arthritis & rheumatology (Hoboken, N.J.) · 2026 · Journal Article
Klein B, Colesa DJ, Gao Y, O'Brien PA, et al.
Nanoscale advances · 2025 · Journal Article
Nguyen LM, Wang Y, Quynh Vu GT, Hoai Ta QT, et al.
HCA healthcare journal of medicine · 2025 · Case Reports
Thomas R, Nguyen NT, Bao D, Tang J, et al.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025 · Journal Article
Landi A, Mahfoud F, Frigoli E, Chalkou K, et al.
Seminars in arthritis and rheumatism · 2024 · Journal Article
Szilagyi IA, Nguyen NL, Boer CG, Schiphof D, et al.
Medical archives (Sarajevo, Bosnia and Herzegovina) · 2024 · Case Reports
Tuan PM, Quang NN, Hung PM, Than LX
Retinal cases & brief reports · 2023 · Case Reports
Nguyen MP, Nguyen NH, Nguyen HPT, Yang CM
Drug delivery · 2022 · Journal Article
Pham DT, Thao NTP, Thuy BTP, Tran V, et al.
BMC rheumatology · 2022 · Journal Article
Shaw YP, Hustek S, Nguyen N, Starlin M, et al.
Frontiers in endocrinology · 2022 · Journal Article
Lincoln S, Morse LR, Troy K, Mattson N, et al.
Molecular therapy : the journal of the American Society of Gene Therapy · 2022 · Journal Article
Truong VA, Lin YH, Nguyen NTK, Hsu MN, et al.
Current rheumatology reviews · 2022 · Journal Article
Minh NN, Nguyen NPT, Ngoc CN, Duy TT, et al.
Journal of shoulder and elbow surgery · 2021 · Journal Article
Logli AL, Pareek A, Nguyen NTV, Sanchez-Sotelo J
Rheumatology (Oxford, England) · 2026 · Journal Article
Antovic A, Nguyen NV, Gunnarsson I, Sandström A, et al.
The Lancet. Rheumatology · 2025 · Journal Article
Nguyen NV, Sandström A, Svenungsson E, Dominicus A, et al.
European cytokine network · 2025 · Journal Article
Dorgham K, Da Mata Jardin O, Mellot C, Mouries-Martin S, et al.
PloS one · 2026 · Journal Article
Nguyen HP, Nguyen TTP, Nguyen NQ, Van Bui T, et al.
Medicine · 2026 · Journal Article
Nguyen Tung B, Quoc Thai N, Manh Hung P, Ngoc Quang N, et al.
Journal of clinical medicine · 2023 · Journal Article
Phong PD, Tung BN, Hung PM, Quang NN, et al.
The Lancet. Rheumatology · 2025 · Journal Article
Nguyen NV, Sandström A, Svenungsson E, Dominicus A, et al.
Rheumatology (Oxford, England) · 2025 · Journal Article
Dominicus A, Mageau A, Nguyen NV, Blomkvist Sporre K, et al.
Rheumatology (Oxford, England) · 2025 · Journal Article
Nguyen NV, Svenungsson E, Dominicus A, Altman M, et al.
EJC paediatric oncology · 2024 · Journal Article
Orimoloye HT, Nguyen N, Deng C, Saechao C, et al.
Pediatrics international : official journal of the Japan Pediatric Society · 2023 · Journal Article
Luong PT, Nguyen TTD, Nguyen NT, Ngo HT, et al.
Dermatology and therapy · 2021 · Journal Article
Nguyen HT, Pham NTU, Tran TNA, Nguyen NTT, et al.
Pediatrics international : official journal of the Japan Pediatric Society · 2023 · Journal Article
Luong PT, Nguyen TTD, Nguyen NT, Ngo HT, et al.
BMC rheumatology · 2025 · Journal Article
Nguyen NX, Pham NT, Le HTT, Tran QV, et al.
Trials · 2024 · Clinical Trial, Phase I
Nguyen NT, Phan HT, Le PM, Nguyen LT, et al.
International journal of molecular sciences · 2022 · Journal Article
Nguyen NT, Sun WH, Chen TH, Tsai PC, et al.
Trials · 2024 · Clinical Trial, Phase I
Nguyen NT, Phan HT, Le PM, Nguyen LT, et al.
Annals of medicine and surgery (2012) · 2024 · Journal Article
Nguyen N, Nguyen NQ, Trinh LNP, Duong TM, et al.
Journal of investigative medicine high impact case reports · 2026 · Journal Article
Nguyen NP, Le TDV, Nguyen N, Chakraborty A, et al.
PloS one · 2026 · Journal Article
Nguyen HP, Nguyen TTP, Nguyen NQ, Van Bui T, et al.
Cureus · 2025 · Case Reports
Nguyen NQ, Dang DA, Le TT, Le TT, et al.
MolPLA: A Molecular Pretraining Framework for Learning Cores, R-Groups and their Linker Joints
Molecular core structures and R-groups are essential concepts in drug development. Integration of these concepts with conventional graph pre-training approaches can promote deeper understanding in molecules. We propose M
EquiCPI: SE(3)-Equivariant Geometric Deep Learning for Structure-Aware Prediction of Compound-Protein Interactions
Accurate prediction of compound-protein interactions (CPI) remains a cornerstone challenge in computational drug discovery. While existing sequence-based approaches leverage molecular fingerprints or graph representation
Towards Accurate and Efficient Waste Image Classification: A Hybrid Deep Learning and Machine Learning Approach
Automated image-based garbage classification is a critical component of global waste management; however, systematic benchmarks that integrate Machine Learning (ML), Deep Learning (DL), and efficient hybrid solutions rem
ISIC 2017 Skin Lesion Segmentation Using Deep Encoder-Decoder Network
This paper summarizes our method and validation results for part 1 of the ISBI Challenge 2018. Our algorithm makes use of deep encoder-decoder network and novel skin lesion data augmentation to segment the challenge obje
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).
Rheumatology (Oxford, England) · 2025 · Journal Article
Dominicus A, Mageau A, Nguyen NV, Blomkvist Sporre K, et al.
The American journal of gastroenterology · 2025 · Journal Article
Nguyen NV, Sandström A, Dominicus A, Mageau A, et al.
Arthritis & rheumatology (Hoboken, N.J.) · 2025 · Journal Article
Nguyen NV, Sandström A, Dominicus A, Svenungsson E, et al.
Current rheumatology reports · 2024 · Journal Article
Klein B, Nguyen NTK, Moallemian R, Kahlenberg JM
Annals of the rheumatic diseases · 2021 · Journal Article
Boer CG, Szilagyi I, Nguyen NL, Neogi T, et al.