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MME CLAUDIE MURATET-ALAUZE

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Auteur de référence en rhumatologie
24 articles scientifiques publiés — un praticien à la pointe de la recherche

Rhumatologue

RPPS 10000365758

✨ Génération du profil synthétique IA en cours…

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Top publications · les plus citées

Systemic Lupus Erythematosus: Old and New Susceptibility Genes versus Clinical Manifestations

Current genomics · 2014

📚 30 citations🎯 RCR 1.08🔓 Open Access

Serratiopeptidase: An integrated View of Multifaceted Therapeutic Enzyme

Biomolecules · 2022

📚 24 citations🎯 RCR 3.32Top 14% NIH🔓 Open Access📄 PDF gratuit ↗

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Microbial products have been used for the treatment of different diseases for many centuries. The serratiopeptidase enzyme provides a new hope for COVID-19-infected patients. Nowadays, anti-inflammatory drugs are easy to obtain at minimal expenditure from microbial sources. Serratia sp. is identified as one of the most efficient bacteria produced from serratiopeptidase. Screening for new and efficient bacterial strains from different sources has been of interest in recent years. Serratiopeptidase remains the most well-known anti-inflammatory drug of choice. Serratiopeptidase is a cheaper and safer anti-inflammatory drug alternative to NSAIDs. The multifaceted properties of serratiopeptidase may lead towards arthritis, diabetes, cancer and thrombolytic treatments. Existing serratiopeptidase treatments in combination with antibiotics are popular in the treatment of postoperative swelling. Although an exclusive number of serratiopeptidase-producing strains have been derived, there is an urge for new recombinant strains to enhance the production of the enzyme. This review explores the properties of serratiopeptidase, different therapeutic aspects, industrial production, and various analytical techniques used in enzyme recovery. In addition, the review highlights the therapeutic and clinical aspects of the serratiopeptidase enzyme to combat COVID-19-induced respiratory syndrome.

A positive association between foot posture index and medial compartment knee osteoarthritis in moroccan people

The open rheumatology journal · 2014

📚 23 citations🎯 RCR 1.32🔓 Open Access📄 PDF gratuit ↗

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Objectives : To compare foot posture in people with and without medial compartment knee osteoarthritis (OA), and to assess association between its abnormalities and medial compartment knee OA. Methods : We compared the foot posture of patients with clinically and radiographically-confirmed medial compartment knee OA and asymptomatic healthy controls using the foot posture index (FPI), navicular height, and the medial arch. Results : We included 100 patients and 80 asymptomatic controls. The mean age of patients was 59 ± 7 (44-76) years and 48 ± 9 (28-60) years in the control (p=0.06). Patients group have more pronated foot for FPI (1.50 ± 2.68 vs 0.72 ± 2.63; p=0.05), more flat foot (42% vs 22%; p=0.03), and less pes cavus than the control group (58% vs 77%; p=0.004). However, there was no significant difference between the groups in the navicular height (3.90 ± 0.85 cm vs 4.00 ± 0.76 cm; p=0.41). In multivariate statistical analysis, after adjusting for age and body mass index, pronated foot in FPI (OR=1.22, 95%IC= [1.06-1.40], p=0.005), and pes cavus (OR=0.32, 95%IC= [0.11-0.93], p=0.03) had a significant correlation with the knee osteoarthritis. Conclusion : Pronated foot posture and flat foot are significantly associated with medial compartment knee osteoarthritis.

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MME CLAUDIE MURATET-ALAUZE

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Top publications · les plus citées

Publications scientifiques (24) — classées par pathologie

Transversal13

Case report / série5

Lupus3

Revue générale2

Corticothérapie1

Pédiatrie1

SAPL1

Vascularites des gros vaisseaux1

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