📇 Rhumatologue · BONDIGOUX · (31) · Salarié

MME Sophie MICHAUD

Pourquoi vous devez consulter ce praticien

3 raisons identifiées

Praticien-chercheur
19 articles scientifiques publiés — formation continue solide
Expérience confirmée
33 ans d'exercice en rhumatologie — recul clinique solide
Délais de RDV courts dans la région
146.3 rhumatos / 100 000 hab. — département bien doté

Rhumatologue

📍 BONDIGOUX (31)SalariéRPPS 10001660454

Expérience confirmée

33ans d'exercice (thèse 1993)

📊 Reconnaissance scientifique : 22/100📝 42 articles publiés🇫🇷 Publications académiques françaises (4)

✨ Génération du profil synthétique IA en cours…

Thèses universitaires

Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.

Top publications · les plus citées

A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality

The New England journal of medicine · 2005

📚 1549 citations🎯 RCR 46.57Top 0% NIH

Host and pathogen factors for Clostridium difficile infection and colonization

The New England journal of medicine · 2011

📚 647 citations🎯 RCR 22.09Top 1% NIH🔓 Open Access📄 PDF gratuit ↗

Comparison of the Directigen flu A+B test, the QuickVue influenza test, and clinical case definition to viral culture and reverse transcription-PCR for rapid diagnosis of influenza virus infection

Journal of clinical microbiology · 2003

📚 145 citations🎯 RCR 3.62Top 12% NIH🔓 Open Access

Lire l'abstract Crossref ↓

ABSTRACT The diagnostic performances of the clinical case definition of influenza virus infection based on the combination of fever and cough and of two rapid influenza diagnostic tests, the Directigen Flu A+B test (Directigen; BD Diagnostic Systems, Sparks, Md.) and the QuickVue influenza test (QuickVue; Quidel, San Diego, Calif.), were compared to those of viral culture and an in-house reverse transcription (RT)-PCR during the 2000-2001 flu season. Two hundred consecutive nasopharyngeal aspirates were analyzed from 192 patients, including 122 adults and 70 children. Viral culture identified influenza virus A in 16 samples and influenza virus B in 55 samples, whereas RT-PCR identified influenza virus A in 21 samples and influenza virus B in 64 samples. When RT-PCR was used as the reference standard, the likelihood ratios for a positive test were 40.0 for Directigen, 8.6 for QuickVue, and 1.4 for the combination of fever and cough, whereas the likelihood ratios for a negative test were 0.22, 0.16, and 0.48, respectively. Our study suggests that (i) the poor specificity (35 to 58%) and the poor positive predictive value (41 to 60%) of the clinical case definition of influenza preclude its use for prediction of influenza virus infections during epidemics, especially when infection control decision making in the hospital setting is considered; (ii) Directigen has a higher diagnostic yield than QuickVue but is associated with a larger number of invalid results; (iii) the sensitivities of the rapid diagnostic tests are significantly lower with samples from adults than with samples from children, with the rates of false-negative results reaching up to 29%; and (iv) RT-PCR detects more cases of influenza than viral culture, and this greater accuracy makes it a more useful reference standard.

Cookies & analyse de trafic

MME Sophie MICHAUD

Pourquoi vous devez consulter ce praticien

Thèses universitaires

Activité de recherche & publications

Publications académiques en France

Lieu de consultation

Tarifs & secteur de conventionnement

Prendre rendez-vous & contact

Top publications · les plus citées

Publications scientifiques (19) — classées par pathologie

Transversal16

Lombalgie2

Génétique1

Datasets & protocoles partagés

Partager cette fiche