📇 Rhumatologue · CERGY · (95) · Hospitalier
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3 raisons identifiées
Auteur de référence en rhumatologie
27 articles scientifiques publiés — un praticien à la pointe de la recherche
Référence presse grand public
Cité 1 fois dans les médias — pédagogie reconnue
Délais de RDV courts dans la région
82.6 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CABINET DU DR CHRISTELLE MICALLEF-FRANCK
16 CHEMIN DUPUIS VERT, 95000 CERGY
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).
📰 Actu.fr · 01/12/2021
<a href="https://news.google.com/rss/articles/CBMi3wFBVV95cUxPN0NqZU5tTGZCQy1vcFFpOWRFdXJOVmphOF9ma1ZGS3FuNlJ2RTRGM3g0elVNNG9VZHl6YURnT3lJbTkxSHBkbExEVW1VNENPRVNYTFQ5RHN3LVpYQ3VvUUI2M2NHTTc0YWQyVmo0dUhnRUIya3JnUjZLWFVmQklneG9ZM3NkXzhKTi16NTRTMkNoUTZYcGRKcU5BcWdJMkoyRGUxb1JDblFFOFY1cEJ6X1NiWFdmWGFqWm
Journal of cellular and molecular medicine · 2009
AbstractThe human kallikrein‐related peptidases (KLK) are serine proteases whose concentrations are often abnormal in common human malignancies and contribute to neoplastic progression through multifaceted roles. However, little attention has been paid to their synthesis and involvement in the development and dissemination of lung cancer, the leading cause of cancer mortality worldwide. We have analysed the production of KLK6 in normal lung and tumour tissues from patients with non‐small cell lung cancer (NSCLC). KLK6 immunoreactivity was restricted to epithelial cells of the normal bronchi, but most of the cancer samples were moderately or highly immunoreactive, regardless of the histological subtype. In contrast, little or no KLK6 was detected in NSCLC cells. We have developed NSCLC lines expressing wild‐type KLK6 in order to investigate the role of KLK6 in lung cancer biology, and analysed its impact on proliferation. Ectopic KLK6 dramatically enhanced NSCLC cell growth and KLK6‐producing NSCLC cells had accelerated cell cycles, between the G1 and S phases. This was accompanied by a marked increase in cyclin E and decrease in p21. KLK6 production was also associated with enhanced synthesis of c‐Myc, which is known to promote cell‐cycle progression. Finally, examination of specimens from patients with NSCLC revealed that KLK6 mRNA is overexpressed in tumour tissue, and high KLK6 concentrations were associated with lower survival rates. We conclude that a high concentration of KLK6 is an indicator of tumour proliferation and an independent predictive factor in NSCLC.
Current genomics · 2014
Pakistan journal of biological sciences : PJBS · 2007
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
American journal of hematology · 2026 · Letter
Segolene G, Richard L, François L, Muriel F, et al.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025 · Journal Article
G A, C G, C J M, B L, et al.
iScience · 2024 · Journal Article
Chen Y, Li B, Christelle M, Eugene N, et al.
Annals of the rheumatic diseases · 2023 · Letter
C SK, Ahmed S, Shenoy V, Menon AR, et al.
The international journal of cardiovascular imaging · 2021 · Case Reports
Randa T, Christelle E, Rachoin R, Bassam H, et al.
Journal of cellular and molecular medicine · 2009 · Journal Article
Nathalie HV, Chris P, Serge G, Catherine C, et al.
American journal of Alzheimer's disease and other dementias · 2006 · Journal Article
Cortes F, Gillette-Guyonnet S, Nourhashemi F, Christelle C, et al.
Biochemical and biophysical research communications · 2000 · Journal Article
Anne-Valérie R, Christelle D, Yannick F, Norbert P, et al.
Cureus · 2025 · Case Reports
C P, Ann Jose J, Verma G, Priya V L, et al.
Cureus · 2024 · Case Reports
Ramanan A, Balasubramanian V, C R, Sami P
JBJS case connector · 2024 · Case Reports
C A, Raju A, Meleppuram JJ, Nair AV, et al.
Journal of orthopaedic case reports · 2016 · Case Reports
Nekkanti S, C V, Js ST, R R, et al.
Advances in protein chemistry and structural biology · 2026 · Journal Article
Loganathan T, Madhulekha S, Zayed H, C GPD
Lupus · 2023 · Journal Article
Patil A, Shobha V, Shenoy P, S C, et al.
Lupus · 2021 · Journal Article
Yanis R, Bergua C, Christelle B, Maillot F, et al.
European journal of pediatrics · 2024 · Journal Article
Yıldız Ç, Küçükali B, C SSB, Şenol PE, et al.
The Pan African medical journal · 2016 · Journal Article
Giles K, Christelle D, Yannick B, Fricke OH, et al.
International journal of adolescent medicine and health · 2016 · Journal Article
Akoï K, Francoise JP, Aurel C, Laure-Manuella I, et al.
Cureus · 2024 · Case Reports
Ramanan A, Balasubramanian V, C R, Sami P
International review of neurobiology · 2022 · Review
Christelle M, Lise M, Ben M'Barek K
Journal of orthopaedic case reports · 2016 · Case Reports
Nekkanti S, C V, Js ST, R R, et al.
European journal of pediatrics · 2024 · Journal Article
Yıldız Ç, Küçükali B, C SSB, Şenol PE, et al.
Pakistan journal of biological sciences : PJBS · 2007 · Journal Article
Djeneba O, Damintoti K, Denise I, Christelle NW, et al.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024 · Journal Article
Leonardo C, Ermenegildo R, Christof K, Amir J, et al.
The Pan African medical journal · 2016 · Journal Article
Giles K, Christelle D, Yannick B, Fricke OH, et al.
BMJ open · 2024 · Journal Article
Kaduka L, Olale J, Mutai J, Christelle E, et al.
Cureus · 2025 · Case Reports
Lakshme I, C A, Senthil N, Pandurangan V
Cureus · 2026 · Case Reports
R S, Nanda M S, Adalarasan S, Subramanian Y, et al.
Journal of orthopaedic case reports · 2016 · Case Reports
Ay GR, D SR, T C, C K, et al.
Cureus · 2019 · Case Reports
Thomas M, Robert A, Kuruvilla N, C U
Current genomics · 2014 · Journal Article
J de AS, C A, P SG, S C
Pakistan journal of biological sciences : PJBS · 2007 · Journal Article
Djeneba O, Damintoti K, Denise I, Christelle NW, et al.