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📰 La République du Centre · 11/03/2020
<a href="https://news.google.com/rss/articles/CBMi4wFBVV95cUxQZ3RWbm1VcmVacVdxSEJlNnpqTTRpQzdVeEZscE1xSzlSRDJ1YmpITklTeHJDaGo2bmxyaThlZ0JwSDRKWVJvOWpNSXhKcVhuYml4RVhNZV9KQ0tmaXdvRWpQR2k3UURNNFViRGQ3cEt6UFdKZlJsTGxIRXZXbzNoRHFHQzE2RXRuT3VkbnZVdHdxTGxQdU1mNmY3VjNFQmNYUFV6RWNWeDVQZFE4bk1IWlZid0kyV1Q2cn
Bio-medical materials and engineering · 2013
BACKGROUND: In tissue engineering, the endothelialization of vascular scaffold can be a crucial step to improve graft patency. A functional cellularization requires coating surfaces. Since 2003, our group used polyelectrolyte multilayer films (PEMFs) made of poly(allylamine hydrochloride) and polystyren sulfonate to coat luminal surface of blood vessel. Previous results showed that PEMFs have remarkable effect on cellular behavior: adhesion, proliferation, differentiation. However, no method seems adapted for in vitro measurement of the viscoelastic shift after PEMFs buildup. OBJECTIVE: In this present work, we proposed to use a new analytical method based on Brillouin spectroscopy (BS) to investigate the influence PEMFs coating on vessel intrinsic viscoelasticy. METHODS: On human umbilical arteries and rabbit vessels, PEMFs were buildup and the luminal surfaces viscoelasticy were measuring by BS. RESULTS: It seems that these films do not alter dynamic functionality and BS could be an interesting method for understanding the role of the tissue architecture, the interrelation between the different structures constituting the wall and the influence of this architecture on the tissue behavior, especially with the characterized components of the different vascular wall. CONCLUSION: The ability of BS to characterize biological samples opens potential applications in tissue engineering field, especially as a tool for a better understanding of vascular diseases.
Frontiers in health services · 2025
Background Mental health services are operating under significant and sustained pressures. Healthcare professionals and managers are continually making adjustments, often improvised and inconsistent across teams. This study aimed to identify and describe the everyday pressures experienced in community mental health settings and the adaptive strategies used by senior leadership and management staff to respond. The longer-term goal is to inform more coordinated, practical approaches to managing services under pressure. Methods We conducted qualitative semi-structured interviews with 22 senior leadership and management staff from community mental health services within a single NHS Trust in England. Interviews explored the everyday pressures encountered and the strategies adopted in response. Data were analysed thematically using a template analysis approach, guided by our previously developed framework—a taxonomy of pressures and adaptive strategies from earlier studies in surgery and intensive care. Results The main source of pressure was a shortage of staff with the necessary skills and experience to manage increasing patient numbers and complexity. Strategies were categorised as anticipatory (implemented in advance of expected pressures) and on-the-day responses. Most were anticipatory, reflecting limited capacity for real-time adaptation. Common strategies involved controlling patient demand and prioritising urgent cases, flexing staff allocation, and enhancing staff support, supervision, and coordination. Flexible use of external services, such as primary care and voluntary sector resources, was also reported. Conclusions Senior mental health staff employ a broad range of adaptive strategies during periods of pressure to manage patient risk, sustain patient flow, and support staff wellbeing. Compared with acute hospital settings such as surgery and intensive care, anticipatory strategies were more prevalent in mental health services, where day-to-day flexibility is constrained by staffing and service structures. There is significant potential to train clinical leaders and teams in the effective use of adaptive strategies and to improve cross-service coordination. The framework used in this study offers a shared language and a practical menu of options to help mental health services prioritise rising patient demand and safeguard staff wellbeing.
Journal of medical systems · 1991
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Bio-medical materials and engineering · 2013 · Journal Article
Beroud J, Vincent B, Paternotte E, Nguyen VS, et al.
Journal of medical systems · 1991 · Journal Article
Lau F, Vincent D, Fenna D, Goebel R, et al.
Frontiers in health services · 2025 · Journal Article
Buivydaite R, Irving D, Page B, Tiplady B, et al.