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3 raisons identifiées
Auteur de référence en rhumatologie
20 articles scientifiques publiés — un praticien à la pointe de la recherche
Disponibilité géographique
10 lieux d'exercice — choisissez celui qui vous arrange
Délais de RDV courts dans la région
124.6 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
Indicateurs publics agrégés sur 250 M+ d'œuvres scientifiques (OpenAlex, PubMed). Traduits ici en langage patient.
Influence scientifique
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
34
34 articles ont été cités au moins 34fois par d'autres chercheurs — preuve que ses travaux sont repris par la communauté médicale.
h-index
Total citations reçues
6 005
Nombre de fois où d'autres équipes ont mentionné ses publications dans leurs propres travaux.
Publications totales
136
Articles, revues et chapitres référencés dans les bases académiques internationales.
Articles influents
66
Publications ayant marqué leur domaine — chacune citée au moins 10 fois par d'autres chercheurs.
i10-index
Thématiques principales
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.
Soil microbial community structure and carbon dynamics in response to compost and livestock management in grassland soils
2026ArticleAgriculture, Ecosystems & Environment
Plasticity in the brooding cidaroid Ctenocidaris nutrix : a morphological, trophic, and molecular investigation
2026ArticleJournal of the Marine Biological Association of the United Kingdom
MAIL proteins prevent Polycomb silencing to keep genes active
2025ArticleNature Plants
Evaluation of the aesthetic and functional effectiveness of primary closed rhinoseptoplasty: A study of 189 cases.
2025ArticleJournal of Stomatology, Oral and Maxillofacial Surgery
Climate impact on mean annual cycle and interannual variability of CO 2 fluxes in European deciduous broadleaf and evergreen needleleaf forests: insights from observations and state-of-the-art data-driven and process-based models
2025ArticleBiogeosciences
Facteurs de contrôle de la respiration des sols forestiers de moyenne montagne face au changement climatique
2025CongrèsCongrès JES 2025 (Journées d’étude des sols)
Soil organic matter degradability as a function of forest species, a study based on Py-GC–MS analysis
2025ArticleGeoderma
A rapid and accurate method for estimating the temperature sensitivity of soil organic matter (Q10)
2025ArticleEuropean Journal of Soil Science
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
IRM MOBILE NORD VIENNE
26 BD ARISTIDE BRIAND, 86106 CHATELLERAULT CEDEX
SCANNER-IRM DU POITOU CHARENTES
ZI LA REPUBLIQUE II 4 R EUGENE CHEVREUL, 86000 POITIERS
PICTAVIX
38 RUE DU FIEF DE GRIMOIRE, 86000 POITIERS
PICTAVIX
CLINIQUE DE POITIERS 1 RUE DE LA PROVIDENCE, 86000 POITIERS
PICTAVIX
POLE REPUBLIQUE 2 3 RUE EUGENE CHEVREUL, 86000 POITIERS
CENTRE D'IMAGERIE DU PRC
CHU LA MILETRIE 2 R DE LA MILETRIE, 86000 POITIERS
GCS IMAGERIE EN COUPE DU NORD VIENNE
CENTRE HOSPITALIER R DU DOCTEUR LUC MONTAGNIER, 86106 CHATELLERAULT CEDEX
PICTAVIX
24 BOULEVARD ARISTIDE BRIAND, 86100 CHATELLERAULT
SCANNER-IRM DU POITOU-CHARENTES
POLYCLINIQUE DE POITIERS 1 R DE LA PROVIDENCE, 86000 POITIERS
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Genome biology · 2020
Abstract Background Chromatin organizes DNA and regulates its transcriptional activity through epigenetic modifications. Heterochromatic regions of the genome are generally transcriptionally silent, while euchromatin is more prone to transcription. During DNA replication, both genetic information and chromatin modifications must be faithfully passed on to daughter strands. There is evidence that DNA polymerases play a role in transcriptional silencing, but the extent of their contribution and how it relates to heterochromatin maintenance is unclear. Results We isolate a strong hypomorphic Arabidopsis thaliana mutant of the POL2A catalytic subunit of DNA polymerase epsilon and show that POL2A is required to stabilize heterochromatin silencing genome-wide, likely by preventing replicative stress. We reveal that POL2A inhibits DNA methylation and histone H3 lysine 9 methylation. Hence, the release of heterochromatin silencing in POL2A-deficient mutants paradoxically occurs in a chromatin context of increased levels of these two repressive epigenetic marks. At the nuclear level, the POL2A defect is associated with fragmentation of heterochromatin. Conclusion These results indicate that POL2A is critical to heterochromatin structure and function, and that unhindered replisome progression is required for the faithful propagation of DNA methylation throughout the cell cycle.
Legal medicine (Tokyo, Japan) · 2023
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2022
Objectives Methotrexate requires therapeutic drug monitoring in oncology because of narrow therapeutic index, especially the metabolite 7-hydroxymethotrexate exhibits nephrotoxicity. The goal of this study was to evaluate different assays and their impact on clinical decisions. Methods Following routine measurement with Abbott TDxFLx® assay (MTX-TDX), 62 samples were analysed on Architect®i1000 (MTX-ARCHI), Xpand® (ARK/XPND), Indiko® (ARK/INDI), and HPLC (MTX-HPLC) as the reference method. The influence of 7-hydroxymethotrexate was explored on ARK reagent to document the cause of the observed bias. ROC curves were built to study the impact of the method on the discharge thresholds for the patients at three levels. Results Total imprecision was below 2.60% for the methotrexate-ARCHI and close to 10% for both ARK assays for plasma pools. The correlation coefficients were 0.93, 0.93, 0.89 and 0.95, the Bland–Altman difference plot revealed a bias of 0.075, 0.037, 0.049 and –0.002, and the number of results exceeding the TE criteria of 0.1 µM was 17 (27%), 13 (21%), 15 (24%) and 15 (24%) for MTX-TDX, ARK/INDI, ARK/XPND and MTX-ARCHI, respectively. Cross reactivity with 7-hydroxymethotrexate was between 1 and 9%. Overestimation of methotrexate concentration was between –4% and +32%. The most robust clinical level was found to be the highest level (0.2 µM) with ROC curves. Conclusions The authors found the best results for imprecision with chemiluminescent microparticle immunoassay method on methotrexate-ARCHI, with bias below to the RICOS recommendations and best correlation to the reference method. Impact on the threshold values for clinical decision need to be clearly exposed to clinicians.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Facial plastic surgery & aesthetic medicine · 2025 · Letter
Sadati K, Mathieu O, Cetrulo CL Jr, Lellouch AG
Therapie · 2024 · Letter
Couderc S, Djerada Z, Rivals F, Lemaire-Hurtel AS, et al.
Journal of stomatology, oral and maxillofacial surgery · 2024 · Journal Article
Mathieu O, Chaine A, Benassarou M, Combes F, et al.
Legal medicine (Tokyo, Japan) · 2023 · Multicenter Study
Djezzar S, Gaulier JM, Gorgiard C, Chèze M, et al.
International journal of legal medicine · 2023 · Journal Article
Poulain C, Mathieu O, Gouetta V, Baccino É, et al.
Aesthetic plastic surgery · 2026 · Journal Article
Gucuk D, Knoedler L, Niederegger T, Fenske J, et al.
JPRAS open · 2026 · Journal Article
Mathieu O, Henderson D, Ezine E, Serror K, et al.
Frontiers in immunology · 2025 · Journal Article
Henderson D, Knoedler L, Niederegger T, Fenske J, et al.
Therapie · 2022 · Journal Article
Aesthetic plastic surgery · 2026 · Journal Article
Gucuk D, Knoedler L, Niederegger T, Fenske J, et al.
JPRAS open · 2026 · Journal Article
Mathieu O, Henderson D, Ezine E, Serror K, et al.
Frontiers in immunology · 2025 · Journal Article
Henderson D, Knoedler L, Niederegger T, Fenske J, et al.
Practical laboratory medicine · 2026 · Case Reports
Aïn C, Baudriller A, Mathieu O, Cazaubon Y
Annals of translational medicine · 2023 · Case Reports
Lellouch AG, Mathieu O, Cetrulo CL Jr, Ragot E, et al.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 2025 · Journal Article
Mathieu O, Baroudjian B, Sprunger Y, Ezine E, et al.
BMC public health · 2025 · Journal Article
Douine M, Korsec V, Sanna A, Plessis L, et al.
Nucleic acids research · 2024 · Journal Article
He X, Dias Lopes C, Pereyra-Bistrain LI, Huang Y, et al.
Genome biology · 2020 · Journal Article
Bourguet P, López-González L, Gómez-Zambrano Á, Pélissier T, et al.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2022 · Journal Article
Descoeur J, Dupuy AM, Bargnoux AS, Cristol JP, et al.
JPRAS open · 2026 · Letter
Mathieu O, Goutard M, Honart JF, Leymarie N
Frontiers in microbiomes · 2024 · Journal Article
Wang G, Menon S, Wilsack L, Rehak R, et al.
Journal of burn care & research : official publication of the American Burn Association · 2026 · Journal Article
Tobalem B, Serror K, Chatard M, Ghezal S, et al.
Journal of burn care & research : official publication of the American Burn Association · 2026 · Journal Article
Tobalem B, Serror K, Chatard M, Ghezal S, et al.
Journal of stomatology, oral and maxillofacial surgery · 2025 · Journal Article
Bouaoud J, Mathieu O, Mure C, Belloc JB
Additional file 2 of DNA polymerase epsilon is required for heterochromatin maintenance in Arabidopsis
Additional file 2: Table S1. POL2A mutant alleles. Table S2. Protein-coding genes upregulated in pol2a-12, not upregulated in atxr5/6 and not marked by H3K27me3 (n = 174). Table S3. List of primers used in this study. Ta
DNA polymerase epsilon is required for heterochromatin maintenance in Arabidopsis
Abstract Background Chromatin organizes DNA and regulates its transcriptional activity through epigenetic modifications. Heterochromatic regions of the genome are generally transcriptionally silent, while euchromatin is
Estimating the dimension of Thurston spine
For g at least 2, the Thurston spine Pg is the subspace of Teichmueller space Tg , consisting of the marked surfaces for which the set of shortest curves, the systoles, cuts the surface into polygons. Our main result is
Jordan algebras and weight modules
We consider bounded weight modules for the universal central extension ${\mathfrak{sl}}_2(J)$ of the Tits-Kantor-Koecher algebra of a unital Jordan algebra $J$. Universal objects called Weyl modules are introduced and st
Noetherian enveloping algebras of simple graded Lie algebras
It is shown that if the universal enveloping algebra of a simple $\mathbb Z^n$-graded Lie algebra is Noetherian, then the Lie algebra is finite-dimensional.
Free hemoglobin determination atpatients’ bedside to evaluate hemolysis: supplementary data
Background: The authors report the relevance of using a point of care test (Helge R ? ) for free hemoglobindetermination and concordance of the values the with Cobas R ? 8000 and spectrophotometer methods.Results: The wi
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).
Alarcan H, Schnell D, Rouleau S, Chachia A, et al.