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2 raisons identifiées
Auteur de référence en rhumatologie
28 articles scientifiques publiés — un praticien à la pointe de la recherche
Référence presse grand public
Cité 9 fois dans les médias — pédagogie reconnue
✨ Génération du profil synthétique IA en cours…
Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
Norme NF C 20-311 : Sécurité de réalisation : assurer la conformité du produit à sa définition en phase de réalisation Standard
2020CongrèsCongrès Lambda Mu 22 « Les risques au cœur des transitions » (e-congrès) - 22e Congrès de Maîtrise des Risques et de Sûreté de Fonctionnement, Institut pour la Maîtrise des Risques
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
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📰 Le Republicain Lorrain · 06/07/2025
<a href="https://news.google.com/rss/articles/CBMikAFBVV95cUxQYVNIbkZkeTFGN2FsaGxNb05yd3FtUWdNWkJoY3UtbnZQZXZZZkltSk5lOHBvZkt2NDFha1FpTVJubDJSRmNJM2NSdkxPc0Ezc1BENlh6NXVidHFzWkIxc0V3UGJ2ZTNIMm1qTzF5SlpMN1g1NHRlUkdUMzhtOHVzY3NWaUYxbjlLeXpGZ2c5cFc?oc=5" target="_blank">Sarrebourg, lycée Mangin | Bac 2
📰 ladepeche.fr · 13/08/2023
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📰 Le Monde.fr · 03/02/2023
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📰 ladepeche.fr · 14/11/2022
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📰 ladepeche.fr · 10/09/2022
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📰 ladepeche.fr · 14/06/2022
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📰 ladepeche.fr · 14/05/2014
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📰 ladepeche.fr · 28/03/2012
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📰 ladepeche.fr · 19/03/2012
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Arthritis care & research · 2017
ObjectiveB cell–depletion therapy based on rituximab is a therapeutic option for refractory disease in patients with systemic lupus erythematosus (SLE). The aim of this observational study was to document long‐term effects on B cell function by following serum immunoglobulin levels in patients with SLE treated with rituximab in routine clinical practice.MethodsWe included 57 consecutive patients with SLE treated with rituximab and concomitant/sequential immunosuppressants and measured serum total IgG, IgM, and IgA and IgG anti‐dsDNA antibodies, over a median of 48 months most recent followup. Flow cytometry was used prospectively to assess B cell phenotypes in 17 of 57 patients.ResultsTwelve patients (21%) had persistent IgM hypogammaglobulinemia (<0.4 gm/liter), and 4 of 57 (5%) had low IgG (<7 gm/liter) at the most recent followup (range 12–144 months). This was not associated with serious adverse events or high anti–double‐stranded DNA (anti‐dsDNA) antibodies (>1,000 IU/ml; normal <50 IU/ml). Factors predictive of low serum IgM included baseline serum IgM ≤0.8 gm/liter (receiver operator curve analysis) and subsequent therapy with mycophenolate mofetil (MMF; odds ratio 6.8, compared with other immunosuppressants). In patients maintaining normal IgM levels (9 of 17), the frequency of circulating IgD+CD27+ B cells was significantly higher (P = 0.05). At 12 months after rituximab, 7 of 30 SLE patients with baseline anti‐dsDNA ≤1,000 IU/ml had lost seropositivity.ConclusionLower baseline serum IgM levels and sequential therapy with MMF were predictive of IgM hypogammaglobulinemia after rituximab in SLE, but this was not associated with higher levels of anti‐dsDNA antibodies or an increased risk of infections. This provides useful directions for clinicians regarding rituximab and sequential immunosuppressive treatment for patients with SLE.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013
Lupus · 2015
Introduction Anti-RNP autoantibodies occur either in mixed connective tissue disease (MCTD) (with a frequently favorable prognosis), or in systemic lupus erythematosus (SLE) cases with aggressive major organ disease. It is uncertain how to assess for the risk of severe disease in anti-RNP + patients. Methods Following institutional review board-approved protocols, clinical data and blood were collected from patients with known or suspected anti-RNP autoimmunity and normal controls in a cohort study. Samples were screened for parameters of immune activation. Groups were compared based on clinical diagnoses, disease classification criteria, disease activity and specific end-organ clinical manifestations. Results Ninety-seven per cent of patients satisfying Alarcon-Segovia MCTD criteria also met Systemic Lupus International Collaborating Clinic (SLICC) SLE criteria, while 47% of the anti-RNP + SLE patients also met MCTD criteria. Among SLICC SLE patients, MCTD criteria were associated with reduced rates of renal disease (odds ratio (OR) 4.3, 95% confidence interval (CI) 1.3–14.0), increased rates of Raynaud's phenomenon (OR 3.5, 95% CI 1.3–9.5) and increased serum B-cell maturation antigen, transmembrane activator and CAML interactor and TNFα levels. Circulating immune markers and markers of type I interferon activation were not effective at distinguishing clinical subgroups. Conclusions Among anti-RNP patients, the question of MCTD versus SLE is not either/or: most MCTD patients also have lupus. MCTD classification criteria (but not a broad set of immune markers) distinguish a subset of SLE patients at reduced risk for renal disease.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025 · Journal Article
Yi G, Jang Y, Martinez L
Archives of osteoporosis · 2022 · Journal Article
da Silva ARB, Martinez LC, de Medeiros Pinheiro M, Szejnfeld VL
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2016 · Journal Article
Collado MV, Dorado E, Rausch S, Gomez G, et al.
Lupus · 2015 · Journal Article
Carpintero MF, Martinez L, Fernandez I, Romero AC, et al.
Archives of osteoporosis · 2010 · Journal Article
Freemantle N, Cooper C, Roux C, Díez-Pérez A, et al.
Diabetes, metabolic syndrome and obesity : targets and therapy · 2009 · Journal Article
Strack T, Martinez L, Del Prato S, Blonde L, et al.
Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica · 2004 · Case Reports
Hernández F, Rivas S, Avila LF, Encinas JL, et al.
The American journal of managed care · 1999 · Conference Proceedings
Auslander M, Bresloff T, Clark DL, Hillman D, et al.
Lupus · 2021 · Journal Article
Catoggio C, Martínez Muñoz A, Chaparro Del Moral R, Klajn DS, et al.
Arthritis care & research · 2017 · Journal Article
Reddy V, Martinez L, Isenberg DA, Leandro MJ, et al.
Clinical and experimental rheumatology · 2015 · Journal Article
Martínez-Barrio J, Ovalles-Bonilla JG, López-Longo FJ, González CM, et al.
Advances in therapy · 2017 · Journal Article
Martinez L, Penfornis A, Gautier JF, Eschwège E, et al.
Journal of medical economics · 2016 · Comparative Study
Roussel R, Martinez L, Vandebrouck T, Douik H, et al.
Advances in therapy · 2015 · Journal Article
Expert review of pharmacoeconomics & outcomes research · 2013 · Comparative Study
de la Torre I, Valor L, Nieto JC, Hernández-Flórez D, et al.
Actas dermo-sifiliograficas · 2010 · English Abstract
Zaragoza V, Pérez A, Sánchez JL, Oliver V, et al.
Lupus · 2013 · Comparative Study
Mesa A, Somarelli JA, Wu W, Martinez L, et al.
Lupus · 2011 · Journal Article
Somarelli JA, Mesa A, Rodriguez R, Avellan R, et al.
Reumatologia clinica · 2025 · Journal Article
de Abreu P, Cabrera S, Cordovilla D, Román L, et al.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2011 · Journal Article
Roux C, Cooper C, Díez-Pérez A, Martinez L, et al.
Archives of osteoporosis · 2026 · Journal Article
da Rocha-Loures MAA, de Freitas Zerbini CA, de Azevedo E, Martinez LC, et al.
Journal of general internal medicine · 2013 · Journal Article
Sustersic M, Jeannet E, Cozon-Rein L, Maréchaux F, et al.
Clinical rheumatology · 2016 · Journal Article
Martin ES, Schneeberger EE, Aranda FM, Peres SW, et al.
International journal of rheumatic diseases · 2016 · Journal Article
Aranda F, Perés Wingeyer SD, Schneeberger E, Valerio M, et al.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013 · Journal Article
Guillemin F, Martinez L, Calvert M, Cooper C, et al.
Health and quality of life outcomes · 2007 · Journal Article
Martinez L, Consoli SM, Monnier L, Simon D, et al.
Arthritis care & research · 2017 · Journal Article
Reddy V, Martinez L, Isenberg DA, Leandro MJ, et al.
Patient preference and adherence · 2019 · Journal Article
Reach G, Chenuc G, Maigret P, Elias-Billon I, et al.
Reumatologia clinica · 2025 · Journal Article
de Abreu P, Cabrera S, Cordovilla D, Román L, et al.
Archives of osteoporosis · 2026 · Journal Article
da Rocha-Loures MAA, de Freitas Zerbini CA, de Azevedo E, Martinez LC, et al.
Archives of osteoporosis · 2026 · Journal Article
da Rocha-Loures MAA, de Freitas Zerbini CA, de Azevedo E, Martinez LC, et al.
Effectiveness and Persistence of Liraglutide Treatment Among Patients with Type 2 Diabetes Treated in Primary Care and Specialist Settings: A Subgroup Analysis from the EVIDENCE Study, a Prospective, 2-Year Follow-up, Observational, Post-Marketing Study
<strong>Article full text</strong> <br> The full text of this article can be found <b>here</b>.<br> <br> <strong>Provide enhanced digital features for this article</strong><br> If you are an author of this publication an
Effectiveness and Persistence of Liraglutide Treatment Among Patients with Type 2 Diabetes Treated in Primary Care and Specialist Settings: A Subgroup Analysis from the EVIDENCE Study, a Prospective, 2-Year Follow-up, Observational, Post-Marketing Study
<strong>Article full text</strong> <br> The full text of this article can be found <b>here</b>.<br> <br> <strong>Provide enhanced digital features for this article</strong><br> If you are an author of this publication an
Overview of the qualitative phase of SHIPquestionnaire development
<b>Copyright information:</b>Taken from "Studying the Hurdles of Insulin Prescription (SHIP): development, scoring and initial validation of a new self-administered questionnaire"http://www.hqlo.com/content/5/1/53Health
La Victoire de Samothrace, du chef d’oeuvre à la matière
La restauration de la Victoire de Samothrace en 2013-2014 a permis de mettre en œuvre une campagne d’analyses et d’examens sans précédent pour mieux en comprendre son état de conservation et la nature des marbres employé
Overview of the qualitative phase of SHIPquestionnaire development
<b>Copyright information:</b>Taken from "Studying the Hurdles of Insulin Prescription (SHIP): development, scoring and initial validation of a new self-administered questionnaire"http://www.hqlo.com/content/5/1/53Health
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).
Lupus · 2013 · Comparative Study
Mesa A, Somarelli JA, Wu W, Martinez L, et al.
Lupus · 2011 · Journal Article
Somarelli JA, Mesa A, Rodriguez R, Avellan R, et al.
Gautier JF, Martinez L, Penfornis A, Eschwège E, et al.
PharmacoEconomics · 2005 · Journal Article
Freemantle N, Blonde L, Bolinder B, Gerber RA, et al.