📇 Rhumatologue · BREST · (29) · Libéral
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4 raisons identifiées
Praticien-chercheur
10 articles scientifiques publiés — formation continue solide
Cabinet de groupe — continuité de soins
Plusieurs praticiens dans le même cabinet — un confrère peut prendre le relais en cas d'absence
Disponibilité géographique
2 lieux d'exercice — choisissez celui qui vous arrange
Délais de RDV courts dans la région
146.3 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
SELAS DIAMORPHOS - SITE KERAUDREN
R ERNESTINE DE TREMAUDAN, 29200 BREST
IMAGERIE MEDICALE STRASBOURG
21 RUE ALBERT LOUPPE, 29200 BREST
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Clinical rheumatology · 2010
Evidence-based complementary and alternative medicine : eCAM · 2006
Millimeter wave therapy (MWT), a non‐invasive complementary therapeutic technique is claimed to possess analgesic properties. We reviewed the clinical studies describing the pain‐relief effect of MWT. Medline‐based search according to review criteria and evaluation of methodological quality of the retrieved studies was performed. Of 13 studies, 9 of them were randomized controlled trials (RCTs), only three studies yielded more than 3 points on the Oxford scale of methodological quality of RCTs. MWT was reported to be effective in the treatment of headache, arthritic, neuropathic and acute postoperative pain. The rapid onset of pain relief during MWT lasting hours to days after, remote to the site of exposure (acupuncture points), was the most characteristic feature in MWT application for pain relief. The most commonly used parameters of MWT were the MW frequencies between 30 and 70 GHz and power density up to 10 mW cm−2. The promising results from pilot case series studies and small‐size RCTs for analgesic/hypoalgesic effects of MWT should be verified in large‐scale RCTs on the effectiveness of this treatment method.
Journal of cellular and molecular medicine · 2018
AbstractEndogenous nucleic acids and their receptors may be involved in the initiation of systemic autoimmune diseases including rheumatoid arthritis (RA). As the role of the DNA sensing Toll‐like receptor (TLR) 9 in RA is unclear, we aimed to investigate its involvement in the pathogenesis of autoimmune arthritis using three different experimental models of RA. The data obtained revealed involvement of TLR9 in the T cell‐dependent phase of inflammatory arthritis. In rats with pristane‐induced arthritis (PIA), TLR9 inhibition before disease onset reduced arthritis significantly and almost completely abolished bone erosion. Accordingly, serum levels of IL‐6, α‐1‐acid‐glycoprotein and rheumatoid factor were reduced. Moreover, in TLR9−/− mice, streptococcal cell wall (SCW)‐induced arthritis was reduced in the T cell‐dependent phase, whereas T cell‐independent serum‐transfer arthritis was not affected. Remarkably, while TLR7 expression did not change during in vitro osteoclastogenesis, TLR9 expression was higher in precursor cells than in mature osteoclasts and partial inhibition of osteoclastogenesis was achieved only by the TLR9 antagonist. These results demonstrate a pivotal role for TLR9 in the T cell‐dependent phases of inflammatory arthritis and additionally suggest some role during osteoclastogenesis. Hence, endogenous DNA seems to be crucially involved in the pathophysiology of inflammatory autoimmune arthritis.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Immunity · 2023 · Journal Article
Seeling M, Pöhnl M, Kara S, Horstmann N, et al.
Cartilage · 2021 · Journal Article
Wagner G, Lehmann C, Bode C, Miosge N, et al.
Journal of cellular and molecular medicine · 2018 · Journal Article
Fischer A, Abdollahi-Roodsaz S, Böhm C, Niederreiter B, et al.
Evidence-based complementary and alternative medicine : eCAM · 2006 · Journal Article
Usichenko TI, Edinger H, Gizhko VV, Lehmann C, et al.
Revista medica de Chile · 1972 · Clinical Trial
Lehmann C, Andreis M, Contreras V, Bennett L, et al.
Revista medica de Chile · 1975 · Journal Article
Ramirez J, Aguilera S, Lehmann C, Cobos L
Revista medica de Chile · 1975 · English Abstract
Aguilera S, Andreis M, Lehmann C, Ramirez J, et al.
Rheumatology (Oxford, England) · 2008 · Case Reports
Jung N, Owczarczyk K, Hellmann M, Lehmann C, et al.
Clinical rheumatology · 2010 · Journal Article
Jung N, Hellmann M, Hoheisel R, Lehmann C, et al.
Revista medica de Chile · 1972 · Journal Article
Lehmann C, Hurtado R, Valdivieso M, Godoy G, et al.