M LAURENT LAVAL

Rhumatologue

📍 BRIONNE (27)LibéralRPPS 10001883247

📊 Reconnaissance scientifique : 3/100📝 13 articles publiés🇫🇷 Publications académiques françaises (3)

✨ Profil synthétique

IA · 19/05/2026

M. Laurent Laval est un rhumatologue libéral exerçant à Brionne. Ses recherches académiques, bien que peu nombreuses, couvrent des domaines variés tels que le contrôle et la stabilité des systèmes dynamiques. Ses publications sur PubMed suggèrent une implication dans des études portant sur la génétique, la santé mentale, l'épidémiologie et la pédiatrie.

Expertises présumées

Génétique
Santé mentale
Fatigue
Épidémiologie
Pédiatrie
Qualité de vie
PROMs (Patient-Reported Outcome Measures)

Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.

✨ Génération du profil synthétique IA en cours…

Activité de recherche & publications

Indicateurs publics agrégés sur 250 M+ d'œuvres scientifiques (OpenAlex, PubMed). Traduits ici en langage patient.

Influence scientifique

Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.

Top publications · les plus citées

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Journal of extracellular vesicles · 2018

📚 8770 citations🎯 RCR 404.65Top 0% NIH🔓 Open Access📄 PDF gratuit ↗

Lire l'abstract Crossref ↓

ABSTRACT The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell‐released, membranous structures, called exosomes, microvesicles, microparticles, ectosomes, oncosomes, apoptotic bodies, and many other names. However, specific issues arise when working with these entities, whose size and amount often make them difficult to obtain as relatively pure preparations, and to characterize properly. The International Society for Extracellular Vesicles (ISEV) proposed Minimal Information for Studies of Extracellular Vesicles (“MISEV”) guidelines for the field in 2014. We now update these “MISEV2014” guidelines based on evolution of the collective knowledge in the last four years. An important point to consider is that ascribing a specific function to EVs in general, or to subtypes of EVs, requires reporting of specific information beyond mere description of function in a crude, potentially contaminated, and heterogeneous preparation. For example, claims that exosomes are endowed with exquisite and specific activities remain difficult to support experimentally, given our still limited knowledge of their specific molecular machineries of biogenesis and release, as compared with other biophysically similar EVs. The MISEV2018 guidelines include tables and outlines of suggested protocols and steps to follow to document specific EV‐associated functional activities. Finally, a checklist is provided with summaries of key points.

Genomic insights into population history and biological adaptation in Oceania

Nature · 2021

📚 101 citations🎯 RCR 5.56Top 7% NIH🔓 Open Access

Lipid Transport and Metabolism at the Blood-Brain Interface: Implications in Health and Disease

Frontiers in physiology · 2021

📚 100 citations🎯 RCR 7.33Top 4% NIH🔓 Open Access📄 PDF gratuit ↗

Lire l'abstract Crossref ↓

Many prospective studies have shown that a diet enriched in omega-3 polyunsaturated fatty acids (n-3 PUFAs) can improve cognitive function during normal aging and prevent the development of neurocognitive diseases. However, researchers have not elucidated how n-3 PUFAs are transferred from the blood to the brain or how they relate to cognitive scores. Transport into and out of the central nervous system depends on two main sets of barriers: the blood-brain barrier (BBB) between peripheral blood and brain tissue and the blood-cerebrospinal fluid (CSF) barrier (BCSFB) between the blood and the CSF. In this review, the current knowledge of how lipids cross these barriers to reach the CNS is presented and discussed. Implications of these processes in health and disease, particularly during aging and neurodegenerative diseases, are also addressed. An assessment provided here is that the current knowledge of how lipids cross these barriers in humans is limited, which hence potentially restrains our capacity to intervene in and prevent neurodegenerative diseases.

Cookies & analyse de trafic

M LAURENT LAVAL

Pourquoi vous devez consulter ce praticien

Activité de recherche & publications

Publications académiques en France

Lieu de consultation

Tarifs & secteur de conventionnement

Prendre rendez-vous & contact

Top publications · les plus citées

Publications scientifiques (49) — classées par pathologie

Transversal39

Génétique3

Santé mentale / fatigue3

Épidémiologie & registres1

Pédiatrie1

Qualité de vie / PROMs1

Revue générale1

Partager cette fiche