📇 Rhumatologue ·
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Praticien-chercheur
7 articles scientifiques publiés — formation continue solide
✨ Génération du profil synthétique IA en cours…
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Psychosomatic medicine · 2008
Infection and immunity · 2022
Biofilms are bacterial communities characterized by antibiotic tolerance. Staphylococcus aureus is a leading cause of biofilm infections on medical devices, including prosthetic joints, which represent a significant health care burden. The major leukocyte infiltrate associated with S. aureus prosthetic joint infection (PJI) is granulocytic myeloid-derived suppressor cells (G-MDSCs), which produce IL-10 to promote biofilm persistence by inhibiting monocyte and macrophage proinflammatory activity.
Pediatric emergency care · 2021
Objectives The purpose of this study was to provide an internationally comparable overview of pediatric trauma of the University Hospital of Lausanne to improve the care of children. Methods We analyzed the data from all injured children (<16 years of age) listed in our trauma registry from 2011 to 2016. These children were admitted to the resuscitation room after prehospital triage. Our data were analyzed using descriptive statistics. Results We included 327 children. Sixty-three percent were male, and the median age was 8 years. Severe trauma (Injury Severity Score (ISS), >15) occurred in 97 children. The principal mechanisms of injury were falls (45%), traffic accidents (29%), and burns (14%). The most frequently affected areas were the head and external body regions. Intensive care admissions amounted to 27%. Twenty percent of patients underwent immediate surgery (wound care, neurosurgery, and orthopedic surgery). The overall mortality rate was 5.5%, with a median ISS of 9. The mortality of severe trauma was 17.5%, with a median ISS of 22. Half of the children died within 6 hours. The main causes of death were falls from greater than 5 m and traffic accidents as pedestrians. Conclusions The demographics and patterns of injury in the pediatric trauma population are similar to other European pediatric trauma centers, but the mortality and the severity of injuries can vary (United Kingdom, 3.7%, median ISS of 9; Denmark, 7.3%, median ISS of 9; and Germany, 13.4%, median ISS of 25). The elevated early mortality rate suggests that improvements in prehospital care and early resuscitation could decrease mortality.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Infection and immunity · 2022 · Journal Article
Bertrand BP, Heim CE, West SC, Chaudhari SS, et al.
Scandinavian journal of trauma, resuscitation and emergency medicine · 2009 · Journal Article
Heim C, Schoettker P, Gilliard N, Spahn DR
Surgical technology international · 1994 · Journal Article
Postak PD, Heim CS, Greenwald AS
Psychosomatic medicine · 2008 · Journal Article
Wingenfeld K, Heim C, Schmidt I, Wagner D, et al.
Pediatric emergency care · 2021 · Journal Article
Svantner J, Dolci M, Heim C, Schoettker P
Presse medicale (Paris, France : 1983) · 2016 · Journal Article
Schoettker P, Marcucci CE, Casso G, Heim C
Frontiers in medicine · 2025 · Journal Article
Konjikusic A, Ohrndorf S, Braun T, Kluckow V, et al.