📇 Rhumatologue · MONTFERMEIL · (93) · Salarié
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2 raisons identifiées
Auteur de référence en rhumatologie
26 articles scientifiques publiés — un praticien à la pointe de la recherche
Délais de RDV courts dans la région
78.3 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CHI LE RAINCY MONTFERMEIL
10 R DU GENERAL LECLERC, 93370 MONTFERMEIL
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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
The British journal of dermatology · 2022
Abstract Background Identification of those at risk of more severe psoriasis and/or associated morbidities offers opportunity for early intervention, reduced disease burden and more cost-effective healthcare. Prognostic biomarkers of disease progression have thus been the focus of intense research, but none are part of routine practice. Objectives To identify and catalogue candidate biomarkers of disease progression in psoriasis for the translational research community. Methods A systematic search of CENTRAL, Embase, LILACS and MEDLINE was performed for relevant articles published between 1990 and December 2021. Eligibility criteria were studies involving patients with psoriasis (any age, n ≥ 50) reporting biomarkers associated with disease progression. The main outcomes were any measure of skin severity or any prespecified psoriasis comorbidity. Data were extracted by one reviewer and checked by a second; studies meeting minimal quality criteria (longitudinal design and/or use of methods to control for confounding) were formally assessed for bias. Candidate biomarkers were identified by an expert multistakeholder group using a majority voting consensus exercise, and mapped to relevant cellular and molecular pathways. Results Of 181 included studies, most investigated genomic or proteomic biomarkers associated with disease severity (n = 145) or psoriatic arthritis (n = 30). Methodological and reporting limitations compromised interpretation of findings, most notably a lack of longitudinal studies, and inadequate control for key prognostic factors. The following candidate biomarkers with future potential utility were identified for predicting disease severity: LCE3D, interleukin (IL)23R, IL23A, NFKBIL1 loci, HLA-C*06:02 (genomic), IL-17A, IgG aHDL, GlycA, I-FABP and kallikrein 8 (proteomic), tyramine (metabolomic); psoriatic arthritis: HLA-C*06:02, HLA-B*27, HLA-B*38, HLA-B*08, and variation at the IL23R and IL13 loci (genomic); IL-17A, CXCL10, Mac-2 binding protein, integrin b5, matrix metalloproteinase-3 and macrophage-colony stimulating factor (proteomic) and tyramine and mucic acid (metabolomic); and type 2 diabetes mellitus: variation in IL12B and IL23R loci (genomic). No biomarkers were supported by sufficient evidence for clinical use without further validation. Conclusions This review provides a comprehensive catalogue of investigated biomarkers of disease progression in psoriasis. Future studies must address the common methodological limitations identified herein to expedite discovery and validation of biomarkers for clinical use. What is already known about this topic? The current treatment paradigm in psoriasis is reactive.There is a need to develop effective risk-stratified management approaches that can proactively attenuate the substantial burden of disease.Prognostic biomarkers of disease progression have therefore been the focus of intense research. What does this study add? This review is the first to scope, collate and catalogue research investigating biomarkers of disease progression in psoriasis.The review identifies potentially promising candidate biomarkers for further investigation and highlights common important limitations that should be considered when designing and conducting future studies in this area.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2026 · Journal Article
Metelus S, Vieira MC, Brasileiro M, Griggio TB, et al.
Sage open pediatrics · 2026 · Case Reports
Rania B, Lina B, Ouiam T, El Haddad S, et al.
Spine · 2025 · Journal Article
Haddad S, Jacobs E, Núñez-Pereira S, Ruiz de Villa A, et al.
The Journal of the American Academy of Orthopaedic Surgeons · 2025 · Journal Article
Lachman JR, Haddad SL
Instructional course lectures · 2025 · Journal Article
Lachman JR, Haddad SL
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2023 · Multicenter Study
Dantas-Silva A, Surita FG, Souza R, Rocha L, et al.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2021 · Journal Article
Khanna R, Slovacek H, Liles J, Haddad S, et al.
Journal of medical Internet research · 2020 · Published Erratum
Haddad SM, Souza RT, Cecatti JG, Barreix M, et al.
Journal of medical Internet research · 2020 · Journal Article
Haddad SM, Souza RT, Cecatti JG, Barreix M, et al.
The open rheumatology journal · 2018 · Journal Article
Jaghsi S, Hammoud T, Haddad S
The Journal of bone and joint surgery. American volume · 2015 · Journal Article
Hsu AR, Haddad SL
BMC medical research methodology · 2014 · Journal Article
Lajos GJ, Haddad SM, Tedesco RP, Passini R Jr, et al.
Annals of medicine and surgery (2012) · 2026 · Case Reports
Hamed H, Haddad S, Alabd L, Eddin HS, et al.
Dermatology reports · 2024 · Case Reports
Al Haddad S, Alfawzan A, Alfalah M, Alharbi M
Annals of medicine and surgery (2012) · 2024 · Case Reports
Zkib J, Sattout R, Faour S, Haddad S, et al.
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2018 · Journal Article
Cirelli JF, Surita FG, Costa ML, Parpinelli MA, et al.
PloS one · 2016 · Journal Article
Souza RT, Cecatti JG, Passini R Jr, Tedesco RP, et al.
PloS one · 2014 · Journal Article
Giordano JC, Parpinelli MA, Cecatti JG, Haddad SM, et al.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2024 · Multicenter Study
Sardinha TG, Lajos GJ, Souza RT, Cecatti JG, et al.
PloS one · 2014 · Journal Article
Passini R Jr, Cecatti JG, Lajos GJ, Tedesco RP, et al.
The British journal of dermatology · 2022 · Journal Article
Ramessur R, Corbett M, Marshall D, Acencio ML, et al.
International journal of medical informatics · 2019 · Journal Article
Haddad SM, Souza RT, Cecatti JG
Cureus · 2025 · Case Reports
Abdallah AS, Fadil M, El Haddad S, Allali N, et al.
Annals of medicine and surgery (2012) · 2024 · Case Reports
Zkib J, Sattout R, Faour S, Haddad S, et al.
International journal of spine surgery · 2023 · Journal Article
Haddad S, Pizones J, Raganato R, Safaee MM, et al.
Clinical biomechanics (Bristol, Avon) · 2022 · Journal Article
DiLiberto FE, Vora AM, Wilson WC, Miller SA, et al.
International journal of medical informatics · 2019 · Journal Article
Haddad SM, Souza RT, Cecatti JG
Journal of the peripheral nervous system : JPNS · 2025 · Case Reports
Haddad S, Poh R, Hehir J, Polke JM, et al.
The Burden of Indirect Causes of Maternal Morbidity and Mortality in the Processof Obstetric Transition: A Cross-Sectional Multicenter Study
Abstract Objective The aim of this study is to evaluate the burden of indirect causes of maternal morbidity/mortality in Brazil. Methods Secondary analysis of a multicenter cross-sectional study conducted in 27 referral
The Burden of Indirect Causes of Maternal Morbidity and Mortality in the Processof Obstetric Transition: A Cross-Sectional Multicenter Study
Abstract Objective The aim of this study is to evaluate the burden of indirect causes of maternal morbidity/mortality in Brazil. Methods Secondary analysis of a multicenter cross-sectional study conducted in 27 referral
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).