📇 Rhumatologue · BOURGOIN JALLIEU CEDEX · (38) · Salarié

MME MAGALI FRANCISCO-CHAMBRIER

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3 raisons identifiées

Auteur de référence en rhumatologie
35 articles scientifiques publiés — un praticien à la pointe de la recherche
Expérience confirmée
35 ans d'exercice en rhumatologie — recul clinique solide
Délais de RDV courts dans la région
120.1 rhumatos / 100 000 hab. — département bien doté

Rhumatologue

📍 BOURGOIN JALLIEU CEDEX (38)SalariéRPPS 10002992518

Expérience confirmée

35ans d'exercice (thèse 1991)

✨ Génération du profil synthétique IA en cours…

Thèses universitaires

L'interet du holter tensionnel chez la femme enceinte : a propos de 67 observations
1991
Médecine🎓 Lyon 1
Georges Mellier

Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.

Top publications · les plus citées

Versatile and efficient targeting using a single nanoparticulate platform: application to cancer and Alzheimer's disease

ACS nano · 2012

📚 95 citations🎯 RCR 3.26Top 14% NIH

Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015

BMC genomics · 2016

📚 25 citations🔓 Open Access📄 PDF gratuit ↗

Phase IV postmarketing surveillance study shows continued efficacy and safety of Stempeucel in patients with critical limb ischemia due to Buerger's disease

Stem cells translational medicine · 2021

📚 17 citations🎯 RCR 1.35🩺 Clinique🔓 Open Access📄 PDF gratuit ↗

Lire l'abstract Crossref ↓

Abstract Buerger's disease or thromboangiitis obliterans is a type of obstructive vascular diseases categorized as vasculitis and usually present in 95% of young smoker men. The main pathogenetic mechanism is interplay between immune system and inflammation. Earlier our phase II study has shown that Stempeucel is safe when injected at 2 million cells/kg body weight by virtue of its anti-inflammatory, immunomodulatory, and angiogenetic properties. The present study was conducted to further assess the safety and efficacy of Stempeucel in critical limb ischemia due to Buerger's disease after obtaining approval from Indian FDA based on the data generated in the phase II study. This is an open label, multicenteric phase IV PMS study conducted across India with experienced vascular surgeons. Fifty patients of critical limb ischemia due to Buerger's disease with Rutherford III-5 or III-6 were included in the study and each individual received a dose of 2 million cells/kg body weight of Stempeucel in the calf muscles and around the ulcer. These patients were evaluated over 12 months from drug administration. The present study showed the continued long term efficacy over a period of 12 months follow up in these patients corroborating the result obtained in the previous phase II studies. There was significant improvement in rest pain, ankle systolic pressure, and ankle brachial pressure index with accelerated ulcer healing. In conclusion, the present study shows that the intramuscular administration of Stempeucel continues to be safe, tolerable, and effective alternative treatment in patients with Buerger's disease.

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MME MAGALI FRANCISCO-CHAMBRIER

Pourquoi vous devez consulter ce praticien

Thèses universitaires

Lieu de consultation

Tarifs & secteur de conventionnement

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Top publications · les plus citées

Publications scientifiques (35) — classées par pathologie

Transversal12

Arthrite juvénile2

Économie santé2

Essai clinique2

Vascularites des gros vaisseaux2

csDMARDs1

Épidémiologie & registres1

Génétique1

JAK inhibiteurs1

Lombalgie1

Lupus1

Maladie à IgG41

Pharmacovigilance1

Qualité de vie / PROMs1

Revue générale1

SAPL1

Sjögren1

Spondyloarthrite1

Tendinopathies & SCC1

Vascularites1

Vraie vie / RWE1

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