📇 Rhumatologue · PARIS · (75) · Salarié

MME JENNY FERRIER-BATTNER

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Auteur de référence en rhumatologie
50 articles scientifiques publiés — un praticien à la pointe de la recherche
Délais de RDV courts dans la région
336.2 rhumatos / 100 000 hab. — département bien doté

Rhumatologue

📍 PARIS (75)SalariéRPPS 10000441906

✨ Génération du profil synthétique IA en cours…

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MSP FAIDHERBE
21 R FAIDHERBE, 75011 PARIS
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Top publications · les plus citées

Flavor and Well-Being: A Comprehensive Review of Food Choices, Nutrition, and Health Interactions

Food science & nutrition · 2025

📚 15 citations🎯 RCR 7.44🔓 Open Access📄 PDF gratuit ↗

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ABSTRACTHuman beings are naturally drawn to food flavors and pleasant aromas, which not only guide food choices but also contribute to health by promoting the intake of nutritious foods, aiding digestion, and enhancing emotional well‐being. This review explores the complex relationship between flavor, nutrition, and health, highlighting that flavor perception can be affected by genetic susceptibility, age, culture, gender, and early life experiences. They influence emotional and physiological responses through brain mechanisms, directly affecting food selection and health outcomes. The use of natural flavors enhances the taste of food and encourages healthier food choices. In contrast, the widespread use of artificial flavors, while often boosting food sales, often leads to the overconsumption of less nutritious products, thereby increasing potential health risks. There is a growing trend among health‐conscious consumers that shows a preference for natural and organic flavors, despite challenges such as low bioavailability and limited evidence of their effectiveness. However, advancements in food processing technologies such as microencapsulation and novel extraction methods offer promising tools to improve flavor stability and sensory acceptance, making healthier products more appealing and widely acceptable. In addition, the use of flavor in a strategic manner is most relevant in food reformulation, dietary interventions, and nutrition education, where it can influence consumers to make more health‐conscious and sustainable food choices. Subsequent research needs to focus on human trials to optimize flavor delivery techniques and dosages, along with the role of genetic traits and environmental influences on customized flavor perception. Governments across the world need to impose stricter regulations on synthetic additives to ensure safety and safeguard consumer health.

Complication Rates Are Not Higher After Outpatient Versus Inpatient Fast-Track Total Knee Arthroplasty: A Propensity-Matched Prospective Comparative Study

The Journal of arthroplasty · 2024

📚 8 citations🎯 RCR 2.90Top 17% NIH

Rescue of lysosomal acid lipase deficiency in mice by rAAV8 liver gene transfer

Communications medicine · 2025

📚 4 citations🔓 Open Access📄 PDF gratuit ↗

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Abstract Background Lysosomal acid lipase deficiency (LAL-D) is an autosomal recessive disorder caused by mutations in the LIPA gene, which results in lipid accumulation leading to multi-organ failure. If left untreated, the severe form of LAL-D results in premature death within the first year of life due to failure to thrive and hepatic insufficiency. Weekly systemic injections of recombinant LAL protein, referred as enzyme replacement therapy, is the only available supportive treatment. Method Here, we characterized a novel Lipa −/− mouse model and developed a curative gene therapy treatment based on the in vivo administration of recombinant (r)AAV8 vector encoding the human LIPA transgene under the control of a hepatocyte-specific promoter. Results Here we define the minimal rAAV8 dose required to rescue disease lethality and to correct cholesterol and triglyceride accumulation in multiple organs and blood. Finally, using liver transcriptomic and biochemical analysis, we show mitochondrial impairment in Lipa −/− mice and its recovery by gene therapy. Conclusions Overall, our in vivo gene therapy strategy achieves a stable long-term LAL expression sufficient to correct the disease phenotype in the Lipa −/− mouse model and offers a new therapeutic option for LAL-D patients.

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MME JENNY FERRIER-BATTNER

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Top publications · les plus citées

Publications scientifiques (50) — classées par pathologie

Transversal38

Revue générale4

Épidémiologie & registres3

Case report / série2

Lupus1

Recommandations1

SAPL1

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