📇 Rhumatologue · PARIS · (75) · Salarié

MME SONIA FARAH

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39 articles scientifiques publiés — un praticien à la pointe de la recherche
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Rhumatologue

📍 PARIS (75)SalariéRPPS 10001386852

✨ Génération du profil synthétique IA en cours…

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CDS EDISON CTRE MS SERVICE CENTRAL
44 R CHARLES MOUREU, 75013 PARIS
☎ 0144978740Activité de soin et de pharmacie
IMV 92
31 RUE MARY BESSEYRE, 92170 VANVES
Activité de soin et de pharmacie

Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.

Top publications · les plus citées

Frailty prevalence according to the Survey of Health, Ageing and Retirement in Europe-Frailty Instrument (SHARE-FI) definition, and its variables associated, in patients with symptomatic knee osteoarthritis: findings from a cross-sectional study

Aging clinical and experimental research · 2021

📚 31 citations🎯 RCR 3.26Top 14% NIH🔓 Open Access📄 PDF gratuit ↗

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Abstract Background Frailty is a frequent condition in patients with knee osteoarthritis (KOA). However, there are different constructs on how to define it. Survey of Health, Ageing and Retirement in Europe-Frailty Instrument (SHARE-FI) is one of them. Aim To assess the prevalence of frailty, according to the SHARE-FI definition in patients with symptomatic KOA, and to establish its associated factors. Methods Symptomatic KOA patients were evaluated for pain symptoms, quality of life, comorbidities, ongoing drug therapy, and radiological damage. Patients were categorised according to the SHARE-FI definition into frail, pre-frail, and non-frail, and compared to a group of healthy controls associated by age and gender. Results 170 symptomatic KOA patients (76.5% female, mean age 70.1 years) and 186 healthy controls were included. According to SHARE-FI criteria, 35 patients (20.6%) were categorised frail, 50 (29.4%) pre-frail, and 85 (50%) non-frail. The prevalence of frail or pre-frail subjects was statistically significantly higher in patients with symptomatic KOA. Stratifying the patients according to the frailty categories, frail subjects showed significantly higher mean values of pain. The results from logistic regression analysis revealed that polypharmacy (p = 0.003), pain (p = 0.016) and comorbidities (p = 0.035) were the variables independently associated with frailty in symptomatic KOA. Discussion Frailty or pre-frailty, defined by SHARE-FI, is common in symptomatic KOA. The main factors associated with frailty were polypharmacy, pain and comorbidity burden. Conclusions SHARE-FI can represent an useful tool to define frailty in symptomatic KOA.

Ultrasound and magnetic resonance imaging as diagnostic tools for sarcopenia in immune-mediated rheumatic diseases (IMRDs)

La Radiologia medica · 2022

📚 24 citations🎯 RCR 3.03Top 16% NIH🔓 Open Access📄 PDF gratuit ↗

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AbstractSarcopenia is characterized by loss of muscle mass, altered muscle composition, fat and fibrous tissue infiltration, and abnormal innervation, especially in older individuals with immune-mediated rheumatic diseases (IMRDs). Several techniques for measuring muscle mass, strength, and performance have emerged in recent decades. The portable dynamometer and gait speed represent the most frequently used tools for the evaluation of muscle strength and physical efficiency, respectively. Aside from dual-energy, X-ray, absorptiometry, and bioelectrical impedance analysis, ultrasound (US) and magnetic resonance imaging (MRI) techniques appear to have a potential role in evaluating muscle mass and composition. US and MRI have been shown to accurately identify sarcopenic biomarkers such as inflammation (edema), fatty infiltration (myosteatosis), alterations in muscle fibers, and muscular atrophy in patients with IMRDs. US is a low-cost, easy-to-use, and safe imaging method for assessing muscle mass, quality, architecture, and biomechanical function. This review summarizes the evidence for using US and MRI to assess sarcopenia.

Muscle involvement in systemic lupus erythematosus: multimodal ultrasound assessment and relationship with physical performance

Rheumatology (Oxford, England) · 2022

📚 17 citations🎯 RCR 2.27Top 23% NIH

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AbstractObjectivesThe objectives of this study were (1) to explore US findings for muscle mass, muscle quality and muscle stiffness in SLE patients and healthy subjects; (2) to investigate the relationship between the US muscle findings and physical performance in SLE patients and healthy subjects.MethodsQuadriceps muscle thickness was used for assessment of muscle mass, muscle echogenicity (using a visual semi-quantitative scale and grayscale analysis with histograms) for assessment of muscle quality, and point shear-wave elastography (SWE) for assessment of muscle stiffness in 30 SLE patients (without previous/current myositis or neuromuscular disorders) and 15 age-, sex- and BMI-matched healthy subjects. Hand grip strength tests and short physical performance battery (SPPB) tests were carried out in the same populations.ResultsNo difference was observed between SLE patients and healthy subjects for quadriceps muscle thickness (35.2 mm ±s.d. 6.8 vs 34.8 mm ± s.d. 6.0, respectively, P = 0.79). Conversely, muscle echogenicity was significantly increased in SLE patients (visual semi-quantitative scale: 1.7 ± s.d. 1.0 vs 0.3 ± s.d. 0.5, respectively, P &lt; 0.01; grayscale analysis with histograms: 87.4 mean pixels ± s.d. 18.8 vs 70.1 mean pixels ± s.d. 14.0, respectively, P &lt; 0.01). Similarly, SWE was significantly lower in SLE patients compared with healthy subjects {1.5 m/s [interquartile range (IQR) 0.3] vs 1.6 m/s (IQR 0.2), respectively, P = 0.01}. Muscle echogenicity was inversely correlated with grip strength (visual semi-quantitative scale, Rho: –0.47, P = 0.01; grayscale analysis with histograms, Rho: –0.41, p &lt; 0.01) and SPPB (visual semi-quantitative scale, Rho: –0.50, P &lt; 0.01; grayscale analysis with histograms Rho: –0,46, P &lt; 0.01).ConclusionsUS assessment of muscle echogenicity and stiffness is useful for the early detection of muscle involvement in SLE patients.

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MME SONIA FARAH

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Top publications · les plus citées

Publications scientifiques (39) — classées par pathologie

Transversal15

Épidémiologie & registres7

IRM ostéo-articulaire7

Qualité de vie / PROMs3

Revue générale2

Économie santé1

Essai clinique1

IA en rhumatologie1

Lupus1

Rhumatisme psoriasique1

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