📇 Rhumatologue · ST DIZIER CEDEX · (52) · Salarié

M JAMAL ESSAOUD

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Auteur de référence en rhumatologie
29 articles scientifiques publiés — un praticien à la pointe de la recherche
Délais de RDV courts dans la région
85.7 rhumatos / 100 000 hab. — département bien doté

Rhumatologue

📍 ST DIZIER CEDEX (52)SalariéRPPS 10001737641

✨ Génération du profil synthétique IA en cours…

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Top publications · les plus citées

Fecal microbiota transplantation plus immunotherapy in non-small cell lung cancer and melanoma: the phase 2 FMT-LUMINate trial

Nature medicine · 2026

📚 8 citations🎯 RCR 8.00🩺 Clinique🔓 Open Access📄 PDF gratuit ↗

Total Ankle Arthroplasty vs Arthrodesis in an HbA(1c)-Defined Diabetic Cohort: Lower 1- to 5-Year Structural Complication Rates in a Retrospective Propensity-Matched Study

Foot & ankle international · 2026

📚 1 citations

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Background: Patients with diabetes are at increased risk for postoperative complications after ankle arthrodesis (AA) and total ankle arthroplasty (TAA), yet few studies directly compare outcomes between these procedures in a matched diabetic cohort. This study evaluates outcomes of TAA vs AA in patients with diabetes with end-stage ankle arthritis. Methods: We performed a retrospective cohort study using the TriNetX Research Network. Adults undergoing primary TAA ( Current Procedural Terminology [ CPT ] 27702) or ankle arthrodesis ( CPT 27870 or 29899) between 2005 and 2025 were included. Diabetes was defined by hemoglobin A 1c (HbA 1c ) ≥6.5% recorded at any point within 1 year prior to surgery. Propensity score matching (1:1) was performed using demographic and clinical covariates. Outcomes included 1-year infection and 1-, 3-, and 5-year structural complications and emergency department (ED) visits. ED visits captured all-cause encounters rather than ankle-specific presentations. The pre-specified primary endpoint was 1-year structural complication; secondary endpoints included infection at 1 year and ED visits and structural complications at 3 and 5 years, with FDR applied to secondary outcomes. Risk estimates, Kaplan-Meier analyses, and Benjamini-Hochberg false discovery rate (FDR) correction were applied. Results: After propensity score matching, 255 patients remained in each group. At 1 year, postoperative infection occurred in 5.5% of TAA patients and 9.4% of AA patients; this difference did not meet statistical significance after false discovery rate (FDR) adjustment. ED visits were more common in the AA cohort at 1, 3, and 5 years after FDR correction. Structural complications occurred more frequently in the AA cohort at 1 year (29.8% vs 15.3%; RR 0.51), 3 years (38.8% vs 20.0%; RR 0.52), and 5 years (39.6% vs 21.2%; RR 0.54), and these differences were statistically supported after FDR adjustment. Conclusion: In patients with a recorded HbA 1c ≥6.5% at any point within the previous year undergoing surgery for end-stage ankle arthritis, TAA demonstrated non-inferior structural complication rates across 1-, 3-, and 5-year follow-up without evidence of increased early infection risk after FDR adjustment.

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M JAMAL ESSAOUD

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Top publications · les plus citées

Publications scientifiques (29) — classées par pathologie

Transversal9

Revue générale7

Épidémiologie & registres3

Revue / méta-analyse3

Essai clinique2

Pédiatrie2

Pharmacovigilance2

Biomarqueurs / Auto-Ac1

Case report / série1

Génétique1

IA en rhumatologie1

Microbiote1

Santé mentale / fatigue1

SAPL1

Vraie vie / RWE1

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