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MME ALINE DUMAS-LACOMBE

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Auteur de référence en rhumatologie
23 articles scientifiques publiés — un praticien à la pointe de la recherche

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Top publications · les plus citées

miR-125b is downregulated in systemic lupus erythematosus patients and inhibits autophagy by targeting UVRAG

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2018

📚 36 citations🎯 RCR 1.54

Irisin ameliorates bone loss in ovariectomized mice

Climacteric : the journal of the International Menopause Society · 2020

📚 34 citations🎯 RCR 2.29Top 23% NIH

The Effectiveness of Tuina in Relieving Pain, Negative Emotions, and Disability in Knee Osteoarthritis: A Randomized Controlled Trial

Pain medicine (Malden, Mass.) · 2023

📚 30 citations🎯 RCR 6.74Top 5% NIH🩺 Clinique

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AbstractObjectiveTo evaluate the effectiveness of Tuina in relieving the pain, negative emotions, and disability of patients with knee osteoarthritis (KOA).DesignSingle-center, parallel, randomized controlled trial.SettingShanghai Guanghua Integrated Chinese and Western Medicine Hospital, Shanghai, China.SubjectsAdult patients with KOA who were able to speak Chinese and self-report symptoms were eligible.MethodsA total of 104 patients were randomly allocated to receive the 6-week treatment of Tuina (Tuina group) or celecoxib (celecoxib group). Data on pain, negative emotions, and disability were collected at baseline, at week 2, 4, and 6, and follow-up (1 month after the last treatment). The primary outcomes were the pressure pain thresholds. The secondary outcomes were: (1) numerical rating scale at rest and with movement; (2) Hamilton Anxiety Scale; (3) Hamilton Depression Scale; (4) Western Ontario and McMaster Universities Osteoarthritis Index; and (5) clinical effective rate. The adverse events of the trial were evaluated.ResultsIn total, 99 patients completed the follow-up. Generalized linear mixed models were constructed to analyse the between-group differences. Statistically significant differences were found in the interaction effects (P &lt; .05). In evaluating the group effect, statistical differences were found at week 6 and follow-up (P &lt; .05). Further, all variables showed a time effect (P &lt; .05). A statistical difference in the clinical effective rate was found between the Tuina and celecoxib groups (P &lt; .05).ConclusionsTuina produced superior effects for pain, negative emotions, and disability over time, as compared to celecoxib in patients with KOA.

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MME ALINE DUMAS-LACOMBE

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Publications scientifiques (23) — classées par pathologie

Transversal9

Épidémiologie & registres2

Qualité de vie / PROMs2

Arthrite juvénile1

Biomarqueurs / Auto-Ac1

Case report / série1

csDMARDs1

Essai clinique1

IRM ostéo-articulaire1

Lupus1

Ostéoporose1

Pédiatrie1

Risque cardio-vasculaire1

Vraie vie / RWE1

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