MME Myriam DREXLER

Rhumatologue

📍 DIGNE LES BAINS (04)SalariéRPPS 10001742104

✨ Génération du profil synthétique IA en cours…

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IMMEUBLE FRANÇOIS CUZIN 4 R DE LA GRAVE, 04000 DIGNE LES BAINS
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Top publications · les plus citées

Tibial rotational osteotomy and distal tuberosity transfer for patella subluxation secondary to excessive external tibial torsion: surgical technique and clinical outcome

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014

📚 46 citations🎯 RCR 3.06Top 16% NIH

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AbstractPurposeRecurrent patella subluxation may be secondary to excessive external tibial torsion. The purpose of this study is to evaluate the clinical and radiographic outcome of patients undergoing tibial derotation osteotomy and tibial tuberosity transfer for recurrent patella subluxation in association with excessive external tibial torsion.MethodsA combined tibial derotation osteotomy and tibial tuberosity transfer was performed in 15 knees (12 patients) with recurrent patella subluxation secondary to excessive external tibial torsion. Clinical evaluation was carried out using preoperative and post‐operative Knee Society Score (KSS), Kujala Patellofemoral score, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire, the short form‐12 (SF‐12) and a visual analogue score (VAS) pain scale.ResultsThe median follow‐up period was 84 months (range 15–156) and median patient age was 34 years (range 19–57 years). The median preoperative external tibial torsion was 62° (range 55°–70°), with a median rotational correction of 36° (range 30°–45°) after surgery. Significant improvement (p < 0.05) was found in the KSS part I (37 ± 14 to 89 ± 11 points), KSS part II (25 ± 26 to 85 ± 14 points), Kujala score, the SF‐12 outcome, WOMAC score and VAS score (8.8 ± 1.9 to 2.4 ± 1.5). Two patients had a nonunion of the tibial osteotomy site; one patient required bone grafting, while another patient required revision to total knee arthroplasty.ConclusionPatients presenting with recurrent patella subluxation secondary to excessive external tibial torsion >45° who underwent tibial derotation osteotomy and tibial tuberosity transfer achieved a satisfactory outcome in terms of pain relief and improved function. A significant complication was seen in 2/15 patients.Level of evidenceCase series, Level IV.

Cartilage restoration of the hip using fresh osteochondral allograft: resurfacing the potholes

The bone & joint journal · 2014

📚 41 citations🎯 RCR 2.49Top 21% NIH

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Cartilage defects of the hip cause significant pain and may lead to arthritic changes that necessitate hip replacement. We propose the use of fresh osteochondral allografts as an option for the treatment of such defects in young patients. Here we present the results of fresh osteochondral allografts for cartilage defects in 17 patients in a prospective study. The underlying diagnoses for the cartilage defects were osteochondritis dissecans in eight and avascular necrosis in six. Two had Legg-Calve-Perthes and one a femoral head fracture. Pre-operatively, an MRI was used to determine the size of the cartilage defect and the femoral head diameter. All patients underwent surgical hip dislocation with a trochanteric slide osteotomy for placement of the allograft. The mean age at surgery was 25.9 years (17 to 44) and mean follow-up was 41.6 months (3 to 74). The mean Harris hip score was significantly better after surgery (p < 0.01) and 13 patients had fair to good outcomes. One patient required a repeat allograft, one patient underwent hip replacement and two patients are awaiting hip replacement. Fresh osteochondral allograft is a reasonable treatment option for hip cartilage defects in young patients.Cite this article: Bone Joint J 2014;96-B(11 Supple A):11–16.

Inhibition of nucleotide pyrophosphatase/phosphodiesterase 1: implications for developing a calcium pyrophosphate deposition disease modifying drug

Rheumatology (Oxford, England) · 2018

📚 15 citations

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MME Myriam DREXLER

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Publications scientifiques (8) — classées par pathologie

Transversal7

Pharmacovigilance1

Vraie vie / RWE1

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