📇 Rhumatologue ·
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Medecine et maladies infectieuses · 2008
Pharmacoepidemiology and drug safety · 2024
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Pharmacoepidemiology and drug safety · 2024 · Journal Article
Colas S, Nishikawa T, Dresco I, Kaplan S, et al.
Current medical research and opinion · 2022 · Journal Article
Ehlken B, Nishikawa C, Kaplan S, Dresco I, et al.
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
ABSTRACTPurposeTo assess the impact of the 2018 European additional risk minimisation measures (aRMMs) regarding the use of valproate in women of childbearing potential (WCBP) and during pregnancy.MethodsA cross‐sectional, non‐interventional survey conducted in six European countries among 1982 healthcare professionals (HCPs) (July–October 2020) and 779 WCBP treated with valproate for epilepsy, bipolar disorder or other indications (August 2020–February 2021). HCPs were prescribing physicians (neurologists, psychiatrists, paediatricians and GPs), gynaecologists and pharmacists. Prespecified criteria were defined for success in the dimensions of awareness, knowledge and behaviour (correct answers to ≥ 80% of questions at individual level) and overall success (≥ 90%/80% successful HCPs/patients respectively, in the behaviour dimension and one of the two other dimensions).ResultsHCPs and patients did not meet the success criteria either overall or in any dimension. Highest success rates were in the behaviour dimension for gynaecologists (71.7%), pharmacists (49.7%) and patients (51.2%), and in the awareness dimension for prescribing physicians (23.6%). HCPs reported being unfamiliar with some educational materials and lacked knowledge of detailed prescribing conditions for valproate and the need for contraception regardless of sexual activity. More than 50% of patients were aware of the relevant patient materials and knew about the teratogenic risks of valproate.ConclusionSelf‐reported levels of awareness, knowledge and behaviour varied considerably by HCP type and among patient respondents. Further investigation is needed into why certain measures of the pregnancy prevention programme are not well known and followed, to improve their effectiveness. This will be addressed in a qualitative study which will be based on interviews with HCPs and patients.
Pharmacoepidemiology and drug safety · 2024 · Journal Article
Colas S, Nishikawa T, Dresco I, Kaplan S, et al.
Medecine et maladies infectieuses · 2008 · English Abstract
Dinh A, Bru JP, Dresco I, Janus C, et al.