📇 Rhumatologue ·
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Référence presse grand public
Cité 6 fois dans les médias — pédagogie reconnue
✨ Génération du profil synthétique IA en cours…
Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).
📰 Egora · 30/12/2025
<a href="https://news.google.com/rss/articles/CBMivAFBVV95cUxQSFhMYkkyWjFKVEtXTVZOSU94anJCZ1JIVjduNDZVTWV1YnVwSlROamxwZWNiNGFNUVQ1U18zanBZUzlzR0VwaDhzcWhXb1Q1N1Iybmg3TUJveEFVc3EzVXhyRFhDWWN4eDR5bzlFQWh1WGZ6bUJyTWMyc040R09QUjFJVExHR2J0UTUtRlRvS2VEY2w5OFBuTVZYZGFjVEQ0azNjek50a2ljUFZPMHgxek9vNXRCRGNwbn
📰 Le Progrès · 05/12/2023
<a href="https://news.google.com/rss/articles/CBMitAFBVV95cUxQSTY5QkdFd1U3VVNiaDM3R29IcDloMGtfZkViQ2czbHZCTi1qQXFjQmxFODYxRmRZbUt2ZmczdU04RXkzOEhGOU1TZDgtM1pOTUdlMTkzNE9BZ2J5LUZZbm1GWWpPaVBPbnFzWkNjZUZtUTBIMjliVlY1RE5namcxX2lwSmhzN2ZrMGZOT0ltNTNvbWd6M05hLURzOG85Tmt6cXg4OGpsV2xoaEk3U1hCSDBHUE0?oc=5"
📰 La Montagne · 14/09/2019
<a href="https://news.google.com/rss/articles/CBMiwAFBVV95cUxPSE5xTVFmWDF1Qm9oSTNlOFRQSlZibGlkTzdDcGVUbktfUVZPeklacFZ1eGFUOFRJN2NXbEZHajUtRWI0T3VfWG91SXpDS3lfMlBqcU9vVWJiZ1Nmdmo0QzVaRERxWE1vQVpWLWs2b2F6LUpHNTdtNGVRVVZjdkpRdGl4cjBtaTRqb0hHZjhvcGdSQmFSN0JsZ3FOTl91M3U0ZVVlRHpqVWVRSTNlZ3VRdHJpd3BSSm5paH
📰 Sud Ouest · 13/03/2019
<a href="https://news.google.com/rss/articles/CBMimwFBVV95cUxObWZ0OTFaeFl1aUJCQ0pEbENxVkdUTlhYbXF1Zl9RN01wN0tIY2YwWHhtOU5pZ1BrVUVUSEdtbE5UeUtBQ21pVS1tN3IwcEZqZWtfNGh0Z0ZLb25ZRTFpQTF6OGJRalUxd1c3Z1BqQzkzUWZtaXpaNFBpRGdCemhWUVhWS1FxcmcyWTZPaFhJNHo3TDM0WTBHZVJFRQ?oc=5" target="_blank">Cérémonie de remi
📰 La Provence · 01/02/2016
<a href="https://news.google.com/rss/articles/CBMirwFBVV95cUxPSmFpOE9mVHl6VWhsN1VLTGtJQzROSi0xRmR3dTJtQ0hyR1AxZmhFc19SVnRqR056b2lWbmZIQjhaTms2Q0pRbFRaZ0VveDBBTjVjMFVPZHItMEtrZjRFWVFUOW8wOEdOQW5zTFR0WUh1ajlJU3RMbkw1b0V2bklTZzhsRVNIR3BOSldULUI5RTlJN2M5QW1KUENRLXd3UWxyUUl6Z3d1dVgwZjZGNVNv?oc=5" target=
📰 Le Populaire du Centre · 25/01/2012
<a href="https://news.google.com/rss/articles/CBMilgFBVV95cUxQVWpYWHJYbnVUMkIyaU9vUDRRSFpySWhZbVZaRXBzMXpuTTR3ZWphWXJnclIzS2hfX1B3azVjOXEyR3RNWUVqZGt4SmVxZTB2anRjbnhoWFlpYzktN2pnSEg4VmFrN2xxM0UwZGt1Z0hjMTNtem1aLXdMSVl5cEVJRU5ZQkhCb2pQalVXYVdra0pWQkc3TGc?oc=5" target="_blank">Les sapeurs-pompiers à l
The Journal of rheumatology · 2013
Objective.To review cases of bisphosphonate-related osteonecrosis of the jaw (BRONJ) occurring in association with benign disease and to describe and compare the clinical course and outcome for patients with BRONJ and rheumatoid arthritis (RA) or osteoporosis.Methods.We retrospectively reviewed observations of all patients referred for treatment and followup for BRONJ from January 2007 to December 2011. Only patients with malignant disease were excluded. Demographic data, medical history, maxillofacial findings, BRONJ treatment, and followup were reviewed for each case.Results.Over a 5-year period, we diagnosed 112 patients with BRONJ. Among these patients, 15 received bisphosphonate (BP) treatment for nonmalignant disease (mean age 65.7 ± 19.8 yrs, 80% women). Patients received BP for a variety of reasons: 8 (53%) to prevent osteoporosis in association with underlying RA; 6 (40%) to prevent idiopathic osteoporosis; and 1 (7%) to treat ankle algodystrophy. The mean oral BP exposure period was 48.4 months (median 36 mo). In 13 cases (86.6%), BRONJ was diagnosed following dental extraction. Of the 8 patients with RA, 5 (62.5%) were taking prednisone at the time of the discovery of BRONJ. Major surgery, sequestrectomy, or alveolectomy was performed in 9 patients (60%), all of whom healed within 3 to 36 months (mean 11.5 mo). Comparative analysis of all the variables showed no statistically significant differences between patients with RA and others.Conclusion.ONJ is a rare adverse effect of BP therapy, especially when administered orally. Within the limits of our study, we were unable to demonstrate a difference in BRONJ disease spectrum, clinical course, or outcome between patients with and those without RA.
Nature communications · 2023
Abstract WHIM Syndrome is a rare immunodeficiency caused by gain-of-function CXCR4 mutations. Here we report a decrease in bone mineral density in 25% of WHIM patients and bone defects leading to osteoporosis in a WHIM mouse model. Imbalanced bone tissue is observed in mutant mice combining reduced osteoprogenitor cells and increased osteoclast numbers. Mechanistically, impaired CXCR4 desensitization disrupts cell cycle progression and osteogenic commitment of skeletal stromal/stem cells, while increasing their pro-osteoclastogenic capacities. Impaired osteogenic differentiation is evidenced in primary bone marrow stromal cells from WHIM patients. In mice, chronic treatment with the CXCR4 antagonist AMD3100 normalizes in vitro osteogenic fate of mutant skeletal stromal/stem cells and reverses in vivo the loss of skeletal cells, demonstrating that proper CXCR4 desensitization is required for the osteogenic specification of skeletal stromal/stem cells. Our study provides mechanistic insights into how CXCR4 signaling regulates the osteogenic fate of skeletal cells and the balance between bone formation and resorption.
Scientific reports · 2024
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Nature communications · 2023 · Journal Article
Anginot A, Nguyen J, Abou Nader Z, Rondeau V, et al.
The Journal of rheumatology · 2013 · Journal Article
Lescaille G, Coudert AE, Baaroun V, Javelot MJ, et al.
International journal of pediatric otorhinolaryngology · 2019 · Journal Article
Rouault M, Coudert A, Hermann R, Gillet Y, et al.
Scientific reports · 2024 · Journal Article
Chauffier J, Berger de Gallardo H, Chevalier MF, Kante A, et al.
✨ Profil synthétique
IA · 22/05/2026Le Dr Alain COUDERT est un rhumatologue dont les publications sur PubMed révèlent une implication dans l'étude de pathologies en pédiatrie et du syndrome de Sjögren. Ses travaux de recherche suggèrent une expertise dans le domaine de la rhumatologie pédiatrique et des maladies auto-immunes. Il contribue ainsi à l'avancement des connaissances dans ces domaines spécifiques.
Expertises présumées
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.