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Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.
Gestion des forêts à eau potable
2006ArticleRevue forestière française
Reconciling commercial exploitation of peat with biodiversity in peatland ecosystems (EU Project RECIPE)
2004Congrès7th INTECOL International, Wetlands Conference
Exploitation of northern peatlands and biodiversity maintenance: a conflict between economy and ecology.
2003ArticleFrontiers in Ecology and the Environment
Description d'une platine de microscope à mouvements multiples
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Arthritis & rheumatology (Hoboken, N.J.) · 2018
ObjectiveTo identify the functional single‐nucleotide polymorphisms (SNPs) and mechanisms conferring increased risk of hand osteoarthritis (OA) at the ALDH1A2 locus, which is a retinoic acid regulatory gene.MethodsTissue samples from 247 patients with knee, hip, or hand OA who had undergone joint surgery were included. RNA‐sequencing analysis was used to investigate differential expression of ALDH1A2 and other retinoic acid signaling pathway genes in cartilage. Expression of ALDH1A2 in joint tissues obtained from multiple sites was quantified using quantitative reverse transcription–polymerase chain reaction. Allelic expression imbalance (AEI) was measured by pyrosequencing. The consequences of ALDH1A2 depletion by RNA interference were assessed in primary human chondrocytes. In silico and in vitro analyses were used to pinpoint which, among 62 highly correlated SNPs, could account for the association at the locus.ResultsALDH1A2 expression was observed across multiple joint tissue samples, including osteochondral tissue from the hand. The expression of ALDH1A2 and of several retinoic acid signaling genes was different in diseased cartilage compared to non‐diseased cartilage, with ALDH1A2 showing lower levels in OA cartilage. Experimental depletion of ALDH1A2 resulted in changes in the expression levels of a number of chondrogenic markers, including SOX9. In addition, reduced expression of the OA risk–conferring allele was witnessed in a number of joint tissues, with the strongest effect in cartilage. The intronic SNP rs12915901 recapitulated the AEI observed in patient tissues, while the Ets transcription factors were identified as potential mediators of this effect.ConclusionThe ALDH1A2 locus seems to increase the risk of hand OA through decreased expression of ALDH1A2 in joint tissues, with the effect dependent on rs12915901. These findings indicate a mechanism that may now be targeted to modulate OA risk.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022 · Journal Article
Subiros M, Robert De Latour C, Parenton F, Soulaimana I, et al.
Annales de biologie clinique · 2014 · Editorial
Souberbielle JC, Benhamou CL, Cortet B, Rousière M, et al.
PLANMAP - Deliverable D4.3 - Moon/Von Karman/Leibnitz craters spectral parameters maps
Spectral parameters maps of Von Karman/Leibnitz craters<strong> </strong>on the Moon at 600 m/pixel derived by Chandrayaan-1/M3 data.
PLANMAP - Deliverable D4.4 - Moon/Apollo Basin and Von Karman/Leibnitz craters spectral units maps
Spectral units maps of Apollo Basin and Von Karman/Leibnitz craters on the Moon. PLANMAP deliverable D4.4
PLANMAP - Deliverable D4.3 - Moon/Von Karman/Leibnitz craters spectral parameters maps
Spectral parameters maps of Von Karman/Leibnitz craters<strong> </strong>on the Moon at 600 m/pixel derived by Chandrayaan-1/M3 data.
PLANMAP - Deliverable D4.4 - Moon/Apollo Basin and Von Karman/Leibnitz craters spectral units maps
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
ArticleJ. Phys. Phys. Appl.
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
Background During the COVID-19 pandemic, national and local measures were implemented on the island of Mayotte, a French overseas department in the Indian Ocean with critical socioeconomic and health indicators. Aim We aimed to describe the COVID-19 outbreak in Mayotte from March 2020 to March 2021, with two waves from 9 March to 31 December 2020 and from 1 January to 14 March 2021, linked to Beta (20H/501Y.V2) variant. Methods To understand and assess the dynamic and the severity of the COVID-19 outbreak in Mayotte, surveillance and investigation/contact tracing systems were set up including virological, epidemiological, hospitalisation and mortality indicators. Results In total, 18,131 cases were laboratory confirmed, with PCR or RAT. During the first wave, incidence rate (IR) peaked in week 19 2020 (133/100,000). New hospitalisations peaked in week 20 (54 patients, including seven to ICU). Testing rate increased tenfold during the second wave. Between mid-December 2020 and mid-January 2021, IR doubled (851/100,000 in week 5 2021) and positivity rate tripled (28% in week 6 2021). SARS-CoV-2 Beta variant (Pangolin B.1.351) was detected in more than 80% of positive samples. Hospital admissions peaked in week 6 2021 with 225 patients, including 30 to ICU. Conclusion This massive second wave could be linked to the high transmissibility of the Beta variant. The increase in the number of cases has naturally led to a higher number of severe cases and an overburdening of the hospital. This study shows the value of a real-time epidemiological surveillance for better understanding crisis situations.
Arthritis & rheumatology (Hoboken, N.J.) · 2018 · Journal Article
Shepherd C, Zhu D, Skelton AJ, Combe J, et al.
Spectral units maps of Apollo Basin and Von Karman/Leibnitz craters on the Moon. PLANMAP deliverable D4.4
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).