📇 Rhumatologue · YVETOT · (76) · Salarié
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4 raisons identifiées
Praticien-chercheur
5 articles scientifiques publiés — formation continue solide
Référence presse grand public
Cité 1 fois dans les médias — pédagogie reconnue
Disponibilité géographique
2 lieux d'exercice — choisissez celui qui vous arrange
Délais de RDV courts dans la région
119.2 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CH YVETOT
7 R DU CHAMP DE COURSES, 76190 YVETOT
CENTRE DE SANTE MEDI-CAUX BUS
4 AV DE VERDUN, 76190 YVETOT
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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).
📰 Ouest-France · 20/02/2026
<a href="https://news.google.com/rss/articles/CBMipAJBVV95cUxOM3M4eTBDRUY4UXY0M1dtcGl2Z2VWT0VmZVgxelJYLVR1cGFoZUFMZEFxOEFPWVVCdVBuZVZlRlF1WVc0STdFQ0RCMFhRSUFnbE9LTHdDNkNEWExQX25zZXFvSmZXLTJBM0E5aFEwUXlvNFN3akpSckxzaXZrWmV2aTRIb3RtSExPaFFrNmZ0Sko4WlhUMFdndWJ3THpzR3RtVXRxbVpIVERyd1FZWUxNc242dEpOd3BJbX
Annals of surgical oncology · 2021
Abstract Background The liver-first approach in patients with synchronous colorectal liver metastases (CRLM) has gained wide consensus but its role is still to be clarified. We aimed to elucidate the outcome of the liver-first approach and to identify patients who benefit at most from this approach. Methods Patients with synchronous CRLM included in the LiverMetSurvey registry between 2000 and 2017 were considered. Three strategies were analyzed, i.e. liver-first approach, colorectal resection followed by liver resection (primary-first), and simultaneous resection, and three groups of patients were analyzed, i.e. solitary metastasis, multiple unilobar CRLM, and multiple bilobar CRLM. In each group, patients from the three strategy groups were matched by propensity score analysis. Results Overall, 7360 patients were analyzed: 4415 primary-first, 552 liver-first, and 2393 simultaneous resections. Compared with the other groups, the liver-first group had more rectal tumors (58.0% vs. 31.2%) and higher hepatic tumor burden (more than three CRLMs: 34.8% vs. 24.0%; size > 50 mm: 35.6% vs. 22.8%; p < 0.001). In patients with solitary and multiple unilobar CRLM, survival was similar regardless of treatment strategy, whereas in patients with multiple bilobar metastases, the liver-first approach was an independent positive prognostic factor, both in unmatched patients (3-year survival 65.9% vs. primary-first 60.4%: hazard ratio [HR] 1.321, p = 0.031; vs. simultaneous resections 54.4%: HR 1.624, p < 0.001) and after propensity score matching (vs. primary-first: HR 1.667, p = 0.017; vs. simultaneous resections: HR 2.278, p = 0.003). Conclusion In patients with synchronous CRLM, the surgical strategy should be decided according to the hepatic tumor burden. In the presence of multiple bilobar CRLM, the liver-first approach is associated with longer survival than the alternative approaches and should be evaluated as standard.
HPB : the official journal of the International Hepato Pancreato Biliary Association · 2017
JPEN. Journal of parenteral and enteral nutrition · 1999
From November 1994 to November 1998, 20 children (2.5 to 14 years) received a jejunoileal graft alone (SBTx; n = 10) or in combination with the liver (SBLTx; n = 10 and/or the right colon (5 SBTx). Indications were intractable diarrhea of infancy (n = 8), short bowel syndrome (n = 6), extensive Hirschsprung disease (n = 4), and chronic intestinal pseudoobstruction (n = 2). Immunosuppression included tacrolimus, methylprednisolone, and azathioprine. Current follow‐up ranges from 6 to 54 months. Five patients died (3 SBTx) within the first 2 months. Acute liver rejection occurred in 5 patients during the first 2 months. Sixteen episodes of intestinal rejection during the first 3 months in 11 patients (8 in 4 SBTx) were successfully treated in all but 3 by increasing tacrolimus dose and/or a 3‐day methyprednisolone bolus or required antilymphoglobulins in 3 cases. Surgical complications occurred 8 times after SBLTx and 3 after SBTx. Infectious complications were more frequent in SBLTx recipients. Reversible Epstein‐Barr virus‐related posttransplant lymphoproliferative disease occurred in 3 recipients. Five presented cytomegalovirus infection. The SB graft was removed in 5 recipients (3 chronic rejection). All patients were started with oral and/or enteral feeding from the 7th postoperative day by using either normal food or protein hydrolysate diet. Currently, 10 of 11 children (8 SBLTx) achieved digestive autonomy after 5 to 30 weeks. All recipients gained weight; however, growth velocity remained reduced during the first 6 months because of the steroid therapy. Overall graft and patient survival is higher after SBLTx. Intestinal transplantation is indicated for patients with permanent intestinal failure. However, because parenteral nutrition is generally well tolerated, even for long periods, each indication for transplantation must be weighed carefully in terms of risk and quality of life. (Journal of Parenteral and Enteral Nutrition23:S121‐S125, 1999)
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2018 · Journal Article
Heilbronner C, Merckx A, Brousse V, Allali S, et al.
JPEN. Journal of parenteral and enteral nutrition · 1999 · Journal Article
Goulet O, Jan D, Lacaille F, Colomb V, et al.
Annals of surgical oncology · 2021 · Journal Article
Giuliante F, Viganò L, De Rose AM, Mirza DF, et al.
HPB : the official journal of the International Hepato Pancreato Biliary Association · 2017 · Comparative Study
Regimbeau JM, Cosse C, Kaiser G, Hubert C, et al.
Cancers · 2022 · Journal Article
Innominato PF, Cailliez V, Allard MA, Lopez-Ben S, et al.