📇 Rhumatologue · PARIS · (75) · Libéral

M Olivier BOYER

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5 raisons identifiées

Auteur de référence en rhumatologie
50 articles scientifiques publiés — un praticien à la pointe de la recherche
Encadrant universitaire
Forme la prochaine génération de rhumatologues (5 thèses dirigées)
Référence presse grand public
Cité 5 fois dans les médias — pédagogie reconnue
Disponibilité géographique
3 lieux d'exercice — choisissez celui qui vous arrange
Délais de RDV courts dans la région
336.2 rhumatos / 100 000 hab. — département bien doté

Rhumatologue

📍 PARIS (75)LibéralRPPS 10000517010

Enseignement

📊 Reconnaissance scientifique : 53/100📝 326 articles publiés🇫🇷 Publications académiques françaises (8)🎓 5 thèses dirigées

✨ Génération du profil synthétique IA en cours…

Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.

Articles de presse (5)

Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).

Nouveau directeur général du CHU d'Orléans : 11 candidats seront reçus en entretien sur quinze jours - La République du Centre

📰 La République du Centre · 24/10/2025

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Vague de départs au CHU d'Orléans : le directeur Olivier Boyer a quitté ses fonctions ainsi que trois autres membres de la direction - France 3 Régions

📰 France 3 Régions · 04/09/2025

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Quel bilan pour Olivier Boyer après quinze ans à la tête du CHU d'Orléans ? - La République du Centre

📰 La République du Centre · 04/09/2025

<a href="https://news.google.com/rss/articles/CBMiyAFBVV95cUxNb0hOVUktQ2dkdUo4UDdyQnFKcXM2T3RKOUFUR2lDMV84SEwyTVNWeUh5SVJIS2xvZ0pCZ2dFME01MWJKN2pQU2ZaVTdXWW10VU04SmM5MTNIUFFKcE5xM1RXM0M0MDFiVlV5VW1DWHk4RElUMFFFa2pKeEE0Z29qRkFNOXdZcl90ZGF4Ykt2OWtWSjVBWTYzOGlMXzJxOFBKQmJ3aGFMcVlEUThwbzFtZFpvcWtzV3B0WF

Défi solidaire, mariage et agacements divers... les indiscrétions du 6 juillet dans le Loiret - La République du Centre

📰 La République du Centre · 06/07/2025

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Des ostéopathes en formation à l'hôpital d'Orléans - La République du Centre

📰 La République du Centre · 05/04/2016

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Top publications · les plus citées

IPNA clinical practice recommendations for the diagnosis and management of children with IgA nephropathy and IgA vasculitis nephritis

Pediatric nephrology (Berlin, Germany) · 2025

📚 38 citations🎯 RCR 17.46🩺 Clinique🔓 Open Access📄 PDF gratuit ↗

Lire l'abstract Crossref ↓

Abstract IgA nephropathy and IgA vasculitis with nephritis, albeit rare, represent two relatively frequent glomerular conditions in childhood. Compared to adults, pediatric IgA nephropathy has a more acute presentation, most frequently with synpharyngitic macrohematuria and histologically with more intense inflammation and less intense chronic damage. Management of these conditions is controversial and supported by little high-quality evidence. The paucity of evidence is due to the disease heterogeneity, its inter-ethnic variability, and the difficulty of extrapolating data from adult studies due to the peculiarities of the condition in children. IgA vasculitis with nephritis is a kidney manifestation of a systemic disorder, typical of the pediatric age, in which both the diagnosis of kidney involvement and its management are poorly defined, and an interdisciplinary approach is crucial. Both conditions can have a profound and long-lasting impact on kidney function and the global health of affected children. The International Pediatric Nephrology Association has therefore convened a diverse international group of experts from different disciplines to provide guidance on the recommended management of these conditions in children and to establish common definitions and define priorities for future high-quality, evidence-based collaborative studies for the benefit of children.

IFNγ causes mitochondrial dysfunction and oxidative stress in myositis

Nature communications · 2024

📚 38 citations🎯 RCR 7.16Top 4% NIH🔓 Open Access📄 PDF gratuit ↗

Lire l'abstract Crossref ↓

AbstractIdiopathic inflammatory myopathies (IIMs) are severe autoimmune diseases with poorly understood pathogenesis and unmet medical needs. Here, we examine the role of interferon γ (IFNγ) using NOD female mice deficient in the inducible T cell co-stimulator (Icos), which have previously been shown to develop spontaneous IFNγ-driven myositis mimicking human disease. Using muscle proteomic and spatial transcriptomic analyses we reveal profound myofiber metabolic dysregulation in these mice. In addition, we report muscle mitochondrial abnormalities and oxidative stress in diseased mice. Supporting a pathogenic role for oxidative stress, treatment with a reactive oxygen species (ROS) buffer compound alleviated myositis, preserved muscle mitochondrial ultrastructure and respiration, and reduced inflammation. Mitochondrial anomalies and oxidative stress were diminished following anti-IFNγ treatment. Further transcriptomic analysis in IIMs patients and human myoblast in vitro studies supported the link between IFNγ and mitochondrial dysfunction observed in mice. These results suggest that mitochondrial dysfunction, ROS and inflammation are interconnected in a self-maintenance loop, opening perspectives for mitochondria therapy and/or ROS targeting drugs in myositis.

Radiation therapy improves CAR T cell activity in acute lymphoblastic leukemia

Cell death & disease · 2023

📚 33 citations🎯 RCR 2.57Top 20% NIH🔓 Open Access📄 PDF gratuit ↗

Lire l'abstract Crossref ↓

AbstractAutologous T cells engineered to express a chimeric antigen receptor (CAR) specific for CD19 are approved for the treatment of various CD19+ hematological malignancies. While CAR T cells induce objective responses in a majority of patients, relapse frequently occurs upon loss of CD19 expression by neoplastic cells. Radiation therapy (RT) has been successfully employed to circumvent the loss of CAR targets in preclinical models of pancreatic cancer. At least in part, this reflects the ability of RT to elicit death receptor (DR) expression by malignant cells, enabling at least some degree of CAR-independent tumor killing. In a human model of CD19+ acute lymphoblastic leukemia (ALL), we also observed DR upregulation by RT, both in vitro and in vivo. Moreover, low-dose total body irradiation (LD-TBI) delivered to ALL-bearing mice prior to CAR T cell infusion considerably extended the overall survival benefit afforded by CAR T cells alone. Such an improved therapeutic activity was accompanied by a superior expansion of CAR T cells in vivo. These data encourage the initiation of clinical trials combining LD-TBI with CAR T cells in patients with hematological malignancies.

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M Olivier BOYER

Pourquoi vous devez consulter ce praticien

Direction de thèses

Activité de recherche & publications

Publications académiques en France

Lieux de consultation(3)

Tarifs & secteur de conventionnement

Prendre rendez-vous & contact

Articles de presse (5)

Top publications · les plus citées

Publications scientifiques (50) — classées par pathologie

Transversal33

Pédiatrie8

Biothérapies non-anti-TNF3

Épidémiologie & registres2

Vascularites2

csDMARDs1

IRM ostéo-articulaire1

Lupus1

Revue générale1

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