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Auteur de référence en rhumatologie
50 articles scientifiques publiés — un praticien à la pointe de la recherche
En plein centre-ville
PARIS (75007) — accessible depuis tout le bassin urbain
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336.2 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CABINET DU DR PASCAL BOUSIQUIER
25 AVENUE DE LA BOURDONNAIS, 75007 PARIS
ALK
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Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
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Kidney international · 2025
Annals of surgery · 2026
Objective: To determine the influence of operating room familiarity on surgeon stress. Background: Regulating surgeon stress may improve patient safety. This study evaluated how assisting surgeons and operating room familiarity influence intraoperative heart rate variability among surgeons. Methods: Attending surgeons from 7 specialties within 4 university hospitals in France were enrolled from November 1, 2020 to December 31, 2021. Vagal tone, an indicator of stress derived from heart rate variability, was assessed during the first 5 minutes after incision using the root mean square of successive differences (RMSSD). Higher RMSSD values indicate greater vagal tone. Team familiarity was quantified as the cumulative time the attending and assisting surgeons had operated together in the past, while operating rooms in which the surgeon conducted >10% of their operations were termed familiar. The effect of each on the RMSSD was assessed via a linear mixed-effect model adjusting for the random effect of the surgeon and possible confounders. Results: Overall, 643 surgeries performed by 37 surgeons were included. The median surgeon age was 49 years; 299 (78.4%) were male, and 22 (59.5%) were professors. Surgeons spent an average of 21.2 hours with the assisting surgeon before surgery and conducted 585 (91.0%) of their operations in a familiar operating room. For every 10 additional hours spent operating together, ln(RMSSD) significantly increased by 0.018 (95% CI: 0.003 to 0.033, P =0.016). Familiar operating rooms also tended to increase surgeon ln(RMSSD) [0.098 (95%CI: −0.007 to 0.203, P =0.068)]. Conclusion: Familiar with assisting surgeons and potentially operating rooms, increased surgeon vagal tone. Maintaining a stable operating room environment may improve surgeon stress and patient care.
Journal of investigational allergology & clinical immunology · 2026
Background: Consuming baked milk (BM) may accelerate tolerance in cow’s milk–allergic (CMA) children. In high-risk patients, controlled BM-based oral food challenge (BM-OFC) is recommended, as the benefits can outweigh the risks of a prolonged exclusion diet. Objectives: To identify predictive biomarkers for BM-OFC outcomes in a cohort at high risk of anaphylaxis and compare the OFC thresholds for baked and pasteurized cow's milk protein (CMP). Methods: We performed a prospective study of children (≥12 months to <6 years) with a history of CMA. Testing at diagnosis involved prick testing, specific IgE (sIgE) for CM and components, sIgG4, and the basophil activation test (BAT). Patients underwent a BM-OFC aiming for a cumulative dose of 1 g of CM protein. BM-tolerant children subsequently underwent a CM-OFC to confirm CMA. Results: The study population comprised 50 patients (66% with a history of anaphylaxis). A reaction was recorded during BM-OFC in 36% of patients (39% with anaphylaxis). The median reactivity threshold was 138 mg of CMP. Risk factors for BM allergy included history of anaphylaxis, age >3 years, elevated CM-sIgE and casein-sIgE, and a positive BAT result. The cut-offs were as follows: >5 mm for skin prick testing with casein, ≥8.5 kUA/L for CM-sIgE, and ≥5.7 kUA/L for casein-sIgE. These made it possible to distinguish BM-allergic patients from CMA patients who tolerated BM. Among BM-tolerant patients, the CM-OFC threshold was 270 mg, with 43.8% reacting to <100 mg (40% with anaphylaxis). Conclusions: BM-OFC is not risk-free. Nevertheless, two-thirds of high-risk CMA children were BM-tolerant and benefited from early introduction of BM products. Patient selection can be guided by biomarkers and a prior history of anaphylaxis to baked goods. The reactivity threshold to pasteurized milk was less than half of the tolerated dose of BM (1000 mg).
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Environmental research · 2026 · Journal Article
Moutet L, Adélaïde L, Claron C, Bahri K, et al.
Nature communications · 2026 · Journal Article
Castets J, Buridan M, Toboso Moreno I, Wattelet-Boyer V, et al.
British journal of haematology · 2026 · Journal Article
Sorin B, Azzouguen B, Loustau V, Boutin E, et al.
Annales pharmaceutiques francaises · 2026 · English Abstract
Elisée D, Bintou B, Pascal AD
Clinical chemistry and laboratory medicine · 2026 · Journal Article
Bonnet B, Tolmer E, Pascal B, Godignon M, et al.
The Journal of organic chemistry · 2026 · Journal Article
Mourot B, Naim C, Canard G, Reboh R, et al.
JAMA otolaryngology-- head & neck surgery · 2026 · Journal Article
Scarpa VL, Pascal AB, Chan KC
The journal of allergy and clinical immunology. In practice · 2026 · Journal Article
Anderson B, Pascal C, Butler MGK, Chin AR, et al.
Environmental science & technology · 2026 · Journal Article
Adélaïde L, Génard-Walton M, Guilbert A, Nakamura A, et al.
medRxiv : the preprint server for health sciences · 2026 · Journal Article
Solotchi M, Jing H, Gebauer E, Novick SJ, et al.
World journal of hepatology · 2026 · Letter
Diaz-Cordova ME, Sharma I, Pascal W, Okumura K
Journal of shoulder and elbow surgery · 2026 · Journal Article
Rice SW, Flood MG, Iovanel G, Kaur H, et al.
The Journal of pathology · 2026 · Journal Article
Liu TT, Pascal LE, Ricke EA, Bautista-Ruiz AL, et al.
Trends in cell biology · 2026 · Journal Article
Pascal GJ, Kim S, Xie C, Mondal D, et al.
The Journal of organic chemistry · 2026 · Journal Article
Jbilou C, Bonfils P, Cho YH, Gunther G, et al.
Journal of applied phycology · 2026 · Journal Article
Tan J, Poong SW, Brakel J, Prasedya ES, et al.
Journal of the American Medical Directors Association · 2026 · Journal Article
Piazza KM, Benson J, Pascal C, Hausmann LRM, et al.
British journal of haematology · 2026 · Journal Article
Dupont M, Derouault P, Pascal V, Dmytruk N, et al.
Journal of clinical medicine · 2025 · Journal Article
Banaszek Ł, Wojtkiewicz M, Rudzińska M, Krysiak P, et al.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025 · Case Reports
Benyahia R, Huart A, Javaugue V, Delas A, et al.
Lakartidningen · 2025 · Journal Article
Skarstam R, Long Chen L, Pascal D, Rück C
La Revue du praticien · 2025 · Journal Article
Pascal M, Pirard P
Kidney international · 2025 · Journal Article
Javaugue V, Pascal V, Nasr SH, Bender S, et al.
Biochimie · 2025 · Journal Article
Le Ruyet C, Pascal S, Usunow G, Van Delft P, et al.
European journal of nuclear medicine and molecular imaging · 2025 · Journal Article
Bonnefoy PB, Pascal P, Ceyrat Q, Burg S, et al.
International journal of circumpolar health · 2025 · Journal Article
Milligan C, Greenland S, Storr L, Pascal A, et al.
HemaSphere · 2025 · Letter
Stammler R, Chen P, Debeaupuis O, Zhao LP, et al.
ACS applied materials & interfaces · 2025 · Journal Article
Sanchez-Fuentes D, Rahal A, Desgarceaux R, García L, et al.
Health & place · 2025 · Journal Article
Forceville G, Goria S, Stempfelet M, Corso M, et al.
Journal of forensic sciences · 2025 · Journal Article
Nair CC, Balachandran A, P AM, Philip FK, et al.
Bioinformation · 2025 · Journal Article
Senthil S, I S Kumar S, Palaniappan M, Arumugam B, et al.
Blood cancer journal · 2025 · Letter
Ben Dhia L, Wemeau M, Fenwarth L, Marceau-Renaut A, et al.
Journal of investigational allergology & clinical immunology · 2025 · Journal Article
Calzada D, Bartra J, Serrano C, Riggioni S, et al.
The Lancet. Microbe · 2026 · Journal Article
Petersen AØ, Damholt B, Grove M, Hink J, et al.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026 · Published Erratum
Servitja S, Castro-Henriques M, Álvarez-Busto I, Díez-Franco C, et al.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026 · Journal Article
Servitja S, Castro-Henriques M, Álvarez-Busto I, Díez-Franco C, et al.
Annals of surgery · 2026 · Journal Article
Awtry JA, Skinner SC, Pascal L, Polazzi S, et al.
European journal of nuclear medicine and molecular imaging · 2026 · Journal Article
Bonnefoy PB, Pascal P, Ceyrat Q, Burg S, et al.
Journal of dairy science · 2026 · Journal Article
Arnalot L, Pascal G, Dejean S, Foucras G, et al.
The Journal of nutrition · 2025 · Journal Article
Combes S, Knudsen C, Rumeau M, Pascal G, et al.
Journal of investigational allergology & clinical immunology · 2026 · Journal Article
Domínguez O, Riggioni C, Poyatos E, Jiménez-Feijoo RM, et al.
Critical care explorations · 2025 · Journal Article
Hasson DC, Clover-Brown I, Zepeda-Orozco D, Pascal E, et al.
BMJ quality & safety · 2026 · Journal Article
Piazza KM, Pelcher LR, Whiteside P, Cribbin M, et al.
The Lancet. Microbe · 2026 · Journal Article
Petersen AØ, Damholt B, Grove M, Hink J, et al.
Nature communications · 2026 · Journal Article
Møiniche M, Johansen KH, Parrón-Ballesteros J, Corneliussen JK, et al.
Blood · 2026 · Journal Article
Schavgoulidze A, Perrot A, Leleu X, Cazaubiel T, et al.
European clinical respiratory journal · 2026 · Case Reports
Kazi Z, Jesin S, Ghimire S, Lewis TA, et al.
Case reports in women's health · 2025 · Case Reports
Pascal FK, El Hanna J, Arsalane A, Denakpo JL
Archives of osteoporosis · 2025 · Journal Article
N BV, A MS, A DR, H SG, et al.
Journal of dairy science · 2026 · Journal Article
Arnalot L, Pascal G, Dejean S, Foucras G, et al.
Case reports in women's health · 2025 · Case Reports
Pascal FK, El Hanna J, Arsalane A, Denakpo JL
Environmental research letters : ERL [Web site] · 2025 · Journal Article
Urban A, Huber V, Henry S, Plaza NP, et al.
The journal of knee surgery · 2026 · Journal Article
Horteur C, Gaulin B, Pascal P, Leroy C, et al.