MME Anne BOULIN

Rhumatologue

📍 SURESNES CEDEX (92)SalariéRPPS 10000331172

🇫🇷 Publications académiques françaises (8)

✨ Génération du profil synthétique IA en cours…

Publications académiques en France

Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.

Diagnosis and management of children and adult craniopharyngiomas: a French Endocrine Society/French Society for Paediatric Endocrinology & Diabetes Consensus Statement
2024
Article

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Pituitary MRI characteristics in 297 acromegaly patients based on T2-weighted sequences

Endocrine-related cancer · 2015

📚 72 citations🎯 RCR 3.61Top 13% NIH

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Responses of GH-secreting adenomas to multimodal management of acromegaly vary widely between patients. Understanding the behavioral patterns of GH-secreting adenomas by identifying factors predictive of their evolution is a research priority. The aim of this study was to clarify the relationship between the T2-weighted adenoma signal on diagnostic magnetic resonance imaging (MRI) in acromegaly and clinical and biological features at diagnosis. An international, multicenter, retrospective analysis was performed using a large population of 297 acromegalic patients recently diagnosed with available diagnostic MRI evaluations. The study was conducted at ten endocrine tertiary referral centers. Clinical and biochemical characteristics, and MRI signal findings were evaluated. T2-hypointense adenomas represented 52.9% of the series, were smaller than their T2-hyperintense and isointense counterparts ( P <0.0001), were associated with higher IGF1 levels ( P =0.0001), invaded the cavernous sinus less frequently ( P =0.0002), and rarely caused optic chiasm compression ( P <0.0001). Acromegalic men tended to be younger at diagnosis than women ( P =0.067) and presented higher IGF1 values ( P =0.01). Although in total, adenomas had a predominantly inferior extension in 45.8% of cases, in men this was more frequent ( P <0.0001), whereas in women optic chiasm compression of macroadenomas occurred more often ( P =0.0067). Most adenomas (45.1%) measured between 11 and 20 mm in maximal diameter and bigger adenomas were diagnosed at younger ages ( P =0.0001). The T2-weighted signal differentiates GH-secreting adenomas into subgroups with particular behaviors. This raises the question of whether the T2-weighted signal could represent a factor in the classification of acromegalic patients in future studies.

Efficacy of endoscopic endonasal transsphenoidal surgery for Cushing's disease in 230 patients with positive and negative MRI

Acta neurochirurgica · 2017

📚 53 citations🎯 RCR 3.45Top 13% NIH

Follow-up of coiled intracranial aneurysms: comparison of 3D time-of-flight and contrast-enhanced magnetic resonance angiography at 3T in a large, prospective series

European radiology · 2012

📚 43 citations🎯 RCR 1.99

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MME Anne BOULIN

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Publications académiques en France

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Publications scientifiques (12) — classées par pathologie

Transversal7

IRM ostéo-articulaire2

Pédiatrie2

Recommandations2

Épidémiologie & registres1

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