📇 Rhumatologue · POINTE A PITRE · (971) · Libéral

M ROLLAND AUCAGOS

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Auteur de référence en rhumatologie
50 articles scientifiques publiés — un praticien à la pointe de la recherche
Délais de RDV courts dans la région
104 rhumatos / 100 000 hab. — département bien doté

Rhumatologue

📍 POINTE A PITRE (971)LibéralRPPS 10000008598

✨ Génération du profil synthétique IA en cours…

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Top publications · les plus citées

Exercise training as a cornerstone intervention for sarcopenia: a review

Current opinion in clinical nutrition and metabolic care · 2026

📚 1 citations

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Purpose of review A loss of muscle mass and strength with aging may reflect a generalized and progressive disease known as sarcopenia. Mounting evidence shows that sarcopenia is associated with poor health outcomes in older adults. Currently, no specific drugs are approved for the treatment of sarcopenia. In this context, exercise training has emerged as a cornerstone non-pharmacological strategy to disease management. This narrative review synthesizes evidence on the effects of exercise training on muscle strength, muscle mass, and physical performance in sarcopenic older adults published recently (from 2024 onward). Recent findings Overall, the literature consistently supports resistance training as the primary exercise modality to combat sarcopenia in older adults with formal diagnosis, with multicomponent programs (i.e., involving aerobic exercises and eventually other exercise types, such as balance) offering additional clinical benefits. Novel approaches, including home-based, technology-assisted, and remotely delivered interventions, combined with traditional exercise modalities further expand the range of feasible strategies. Summary Important challenges remain in translating research findings into clinical practice. Continued advances in the definition and operationalization of sarcopenia, alongside well-designed and adequately powered clinical trials, will be essential to refine evidence-based exercise recommendations and to support their effective implementation in real-world settings.

Growth differentiation factor 15 as a biomarker of frailty: evidence from recent studies

Current opinion in clinical nutrition and metabolic care · 2026

📚 1 citations

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Purpose of review Growth differentiation factor 15 (GDF15), a stress- response protein of the TGF-β superfamily, has emerged as a potential biomarker of frailty. This review aims to summarize recent evidence on the association between GDF15 and frailty. Recent findings Emerging data from 14 recent studies, including seven longitudinal and seven cross-sectional investigations, support GDF15 as a promising biomarker for frailty. Longitudinal studies indicate that elevated GDF15 levels are associated with an increased risk of developing frailty and with adverse outcomes related to frailty over follow-up periods of up to 13 years, across both community-dwelling and clinical populations, such as patients with cardiometabolic diseases or postknee replacement. The predictive value of GDF15 appears to vary depending on the frailty assessment tool used. Cross-sectional analyses corroborate longitudinal findings by showing that GDF15 levels are associated to frailty severity across diverse populations (e.g., community-dwelling, acutely hospitalized patients) in a dose--response manner. Summary GDF15 represents a promising biomarker for frailty, reflecting physical decline and risk of future frailty. Future research should address sex-specific effects, standardize assay protocols and frailty assessments, and explore the clinical utility of GDF15 to detect people at increased risk of decline in intrinsic capacity and frailty in a life course perspective.

Next-generation multicenter studies: using artificial intelligence to automatically process unstructured health records of patients with lung cancer across multiple institutions

Annals of oncology : official journal of the European Society for Medical Oncology · 2026

📚 1 citations

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M ROLLAND AUCAGOS

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Top publications · les plus citées

Publications scientifiques (50) — classées par pathologie

Transversal29

Revue générale8

Gériatrie3

Revue / méta-analyse3

Santé mentale / fatigue3

Économie santé2

Essai clinique2

IA en rhumatologie2

Biomarqueurs / Auto-Ac1

Case report / série1

Génétique1

Pharmacovigilance1

Sjögren1

Vascularites des gros vaisseaux1

Vraie vie / RWE1

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