Docteur FREDERIC MARTINS
✨ Profil synthétique
IA · 29/04/2026Le Docteur Frédéric Martins est un rhumatologue hospitalier à Rodez, avec une production scientifique notable dans le domaine de la recherche médicale. Son h-index de 16 et ses 66 publications reflètent son engagement dans la recherche, notamment dans les domaines de l'épidémiologie et de la génétique. Ses travaux publiés sur PubMed couvrent des pathologies telles que le lupus et l'arthrite juvénile, ainsi que l'utilisation d'anti-TNF et de csDMARDs.
Expertises présumées
- Lupus
- Arthrite juvénile
- Traitement par anti-TNF
- Utilisation de csDMARDs
- Épidémiologie des maladies rhumatismales
- Recherche sur les registres de maladies rhumatismales
- Étude des cas de maladies auto-immunes
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- DES Rhumatologie
- Rhumatologie (SM)
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
16
h articles cités ≥ h fois chacun. Un h de 16 = 16 publications avec 16+ citations.
Citations
1 587
Publications
66
i10-index
16
Thématiques principales
- Horticultural and Viticultural Research ×26
- Genetic Mapping and Diversity in Plants and Animals ×18
- Genetic diversity and population structure ×16
- Genetic Associations and Epidemiology ×15
- Genetic and phenotypic traits in livestock ×8
Affiliations FR : Université de Bordeaux · Inserm · Neurocentre Magendie
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Placental Extracellular Vesicles Exhibit Reduced Neurogenic Potential Linked to Changes in Their miRNA Landscape Upon HCMV Infection
2026ArticleJournal of Extracellular Biology
Developmental alterations of indirect-pathway medium spiny neurons in mouse models of Huntington's disease
2025ArticleNeurobiology of Disease
Dynamic conditioning of porcine kidney grafts with extracellular vesicles derived from urine progenitor cells: A proof‐of‐concept study
2024ArticleClinical and Translational Medicine
Human DNA Extraction and Sequencing From Cardiomyocytes Collected by Catheter-Based Aspiration
2024ArticleJournal of the American College of Cardiology
Integrated spatial and multimodal single‐cell transcriptomics reveal patient‐dependent cell heterogeneity in splenic marginal zone lymphoma
2024ArticleJournal of Pathology
Cell specification and functional interactions in the pig blastocyst inferred from single-cell transcriptomics and uterine fluids proteomics
2024ArticleGenomics
Single-cell RNA sequencing identifies senescence as therapeutic target in rhabdomyolysis-induced acute kidney injury
2024ArticleNephrology Dialysis Transplantation
Gene networks controlling functional cell interactions in the pig embryo revealed by omics studies
2023CongrèsEAAP Annual Meeting
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Lieu de consultation
CH DE RODEZ HOPITAL JACQUES PUEL
Avenue DE L'HOPITAL, 12027 Rodez
Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 1Proceedings of the 3rd IPLeiria's International Health Congress : Leiria, Portugal. 6-7 May 2016
BMC health services research · 2016
- 3Single-cell RNA sequencing unveils the shared and the distinct cytotoxic hallmarks of human TCRVδ1 and TCRVδ2 γδ T lymphocytes
Proceedings of the National Academy of Sciences of the United States of America · 2019
Lire l'abstract Crossref ↓
γδ T lymphocytes represent ∼1% of human peripheral blood mononuclear cells and even more cells in most tissues of vertebrates. Although they have important anticancer functions, most current single-cell RNA sequencing (scRNA-seq) studies do not identify γδ T lymphocytes because their transcriptomes at the single-cell level are unknown. Here we show that high-resolution clustering of large scRNA-seq datasets and a combination of gene signatures allow the specific detection of human γδ T lymphocytes and identification of their T cell receptor (TCR)Vδ1 and TCRVδ2 subsets in large datasets from complex cell mixtures. Int-distributed stochastic neighbor embedding plots from blood and tumor samples, the few γδ T lymphocytes appear collectively embedded between cytotoxic CD8 T and NK cells. Their TCRVδ1 and TCRVδ2 subsets form close yet distinct subclusters, respectively neighboring NK and CD8 T cells because of expression of shared and distinct cytotoxic maturation genes. Similar pseudotime maturation trajectories of TCRVδ1 and TCRVδ2 γδ T lymphocytes were discovered, unveiling in both subsets an unattended pool of terminally differentiated effector memory cells with preserved proliferative capacity, a finding confirmed by in vitro proliferation assays. Overall, the single-cell transcriptomes of thousands of individual γδ T lymphocytes from different CMV+and CMV−donors reflect cytotoxic maturation stages driven by the immunological history of donors. This landmark study establishes the rationale for identification, subtyping, and deep characterization of human γδ T lymphocytes in further scRNA-seq studies of complex tissues in physiological and disease conditions.
Publications scientifiques (50) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal33
▼
Transversal33
▼- Placental Extracellular Vesicles Exhibit Reduced Neurogenic Potential Linked to Changes in Their miRNA Landscape Upon HCMV Infection
Journal of extracellular biology · 2026 · Journal Article
Martin C, Martin H, Bergamelli M, Lobjois L, et al.
📚 1 cit. - Methodology of DNA extraction and sequencing from living cardiomyocytes collected by catheter in humans
Genetics in medicine open · 2026 · Journal Article
Ader F, Guilbeau-Frugier C, Lhuillier E, Martins F, et al.
- The use of ASDAS to evaluate disease activity and response to treatment in patients with axial spondyloarthritis starting the first biological drug: Are ASAS recommendations being followed?
Seminars in arthritis and rheumatism · 2025 · Journal Article
Santos ME, Ramiro S, van der Heijde D, Landewé R, et al.
- De novo post-COVID-19 chronic pain: a piece of information about risk factor and clinical features
Pain reports · 2025 · Journal Article
Goncalves FT, Firigato I, Pessotto AV, Carvalho Soares FH, et al.
📚 2 cit.🔬→🩺 Translationnel - Developmental alterations of indirect-pathway medium spiny neurons in mouse models of Huntington's disease
Neurobiology of disease · 2025 · Journal Article
Lebouc M, Bonamy L, Dhellemmes T, Scharnholz J, et al.
📚 3 cit. - Dynamic conditioning of porcine kidney grafts with extracellular vesicles derived from urine progenitor cells: A proof-of-concept study
Clinical and translational medicine · 2024 · Journal Article
Burdeyron P, Giraud S, Lepoittevin M, Jordan N, et al.
📚 2 cit. - Chikungunya-Driven Gene Expression Linked to Osteoclast Survival and Chronic Arthralgia
Infectious disease reports · 2024 · Journal Article
Urbanski AH, Maso VE, Martins FM, da Costa-Martins AG, et al.
📚 1 cit. - Integrated spatial and multimodal single-cell transcriptomics reveal patient-dependent cell heterogeneity in splenic marginal zone lymphoma
The Journal of pathology · 2024 · Journal Article
Cerapio JP, Gravelle P, Quillet-Mary A, Valle C, et al.
📚 2 cit. - Human DNA Extraction and Sequencing From Cardiomyocytes Collected by Catheter-Based Aspiration
Journal of the American College of Cardiology · 2024 · Letter
Maury P, Ader F, Lhuillier E, Martins F, et al.
📚 1 cit. - Cell specification and functional interactions in the pig blastocyst inferred from single-cell transcriptomics and uterine fluids proteomics
Genomics · 2024 · Journal Article
Dufour A, Kurylo C, Stöckl JB, Laloë D, et al.
📚 6 cit. - Single-cell RNA sequencing identifies senescence as therapeutic target in rhabdomyolysis-induced acute kidney injury
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024 · Journal Article
Rao SN, Zahm M, Casemayou A, Buleon M, et al.
📚 8 cit.🎯 RCR 1.22 - Löfgren Syndrome: A Mosaic of Sarcoidosis Phenotypes
Cureus · 2024 · Case Reports
Martins F, Martins M, Malheiro R
📚 1 cit. - Neutrophile to lymphocyte and platelet to lymphocyte ratios predict clinical response to bDMARD in naïve spondylarthritis patients
ARP rheumatology · 2024 · Journal Article
Martins FR, Bernardes M, Sequeira G, Costa L, et al.
📚 1 cit. - Disability prevalent conditions in women
Revista da Associacao Medica Brasileira (1992) · 2023 · Journal Article
Plapler PG, Cecatto RB, Socolowski MD, Martins F
- Immune-mediated skin lesions related to biological disease-modifying antirheumatic drugs: a 22-year experience of a tertiary center
ARP rheumatology · 2023 · Journal Article
Martins A, Oliveira D, Martins FR, Nicolau R, et al.
📚 1 cit. - The impact of antinuclear antibodies seroconversion induced by anti-tumor necrosis factor α agents on the clinical outcomes in rheumatic patients
ARP rheumatology · 2023 · Journal Article
Martins A, Oliveira D, Martins FR, Rato MS, et al.
📚 2 cit. - Clinical characterisation of a multicentre nationwide cohort of patients with antisynthetase syndrome
ARP rheumatology · 2022 · Multicenter Study
Martins P, Dourado E, Melo AT, Samões B, et al.
📚 14 cit.🎯 RCR 1.66 - Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor
Science advances · 2022 · Journal Article
Personnaz J, Piccolo E, Dortignac A, Iacovoni JS, et al.
📚 18 cit.🎯 RCR 1.57 - Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy
Cancer cell · 2022 · Journal Article
Asrir A, Tardiveau C, Coudert J, Laffont R, et al.
📚 194 cit.🎯 RCR 11.64🔬→🩺 Translationnel - Identification of Loci Enabling Stable and High-Level Heterologous Gene Expression
Frontiers in bioengineering and biotechnology · 2021 · Journal Article
Defrel G, Marsaud N, Rifa E, Martins F, et al.
📚 2 cit. - Effects of liquid extract from Plinia cauliflora fruits residues on Chinese hamsters biochemical parameters
Brazilian journal of biology = Revista brasleira de biologia · 2021 · Journal Article
Borges LL, Martins FS, Franco JJ, Bailão EFLC, et al.
📚 1 cit. - Different cutoff points to diagnose low muscle mass and prediction of osteoporosis in postmenopausal women
Menopause (New York, N.Y.) · 2021 · Journal Article
Miranda C, de Morais VFB, Martins FM, Pelet DCS, et al.
📚 3 cit. - The role of opioid analgesics in rheumatic disorders: a position paper from the Portuguese Rheumatology Society
Acta reumatologica portuguesa · 2020 · Journal Article
Azevedo S, Guimarães F, Leite Silva J, Barros R, et al.
📚 1 cit. - Niacin induces miR-502-3p expression which impairs insulin sensitivity in human adipocytes
International journal of obesity (2005) · 2019 · Journal Article
Montastier E, Beuzelin D, Martins F, Mir L, et al.
📚 19 cit.🩺 Clinique - Single-cell RNA sequencing unveils the shared and the distinct cytotoxic hallmarks of human TCRVδ1 and TCRVδ2 γδ T lymphocytes
Proceedings of the National Academy of Sciences of the United States of America · 2019 · Journal Article
Pizzolato G, Kaminski H, Tosolini M, Franchini DM, et al.
📚 176 cit.🎯 RCR 5.78🔬→🩺 Translationnel - Single-Cell Analysis Reveals Heterogeneity of High Endothelial Venules and Different Regulation of Genes Controlling Lymphocyte Entry to Lymph Nodes
Cell reports · 2019 · Journal Article
Veerman K, Tardiveau C, Martins F, Coudert J, et al.
📚 92 cit.🎯 RCR 2.79 - Caloric Restriction and Diet-Induced Weight Loss Do Not Induce Browning of Human Subcutaneous White Adipose Tissue in Women and Men with Obesity
Cell reports · 2018 · Journal Article
Barquissau V, Léger B, Beuzelin D, Martins F, et al.
📚 64 cit.🎯 RCR 2.62🔬→🩺 Translationnel - Muscle transcriptome analysis reveals molecular pathways and biomarkers involved in extreme ultimate pH and meat defect occurrence in chicken
Scientific reports · 2017 · Journal Article
Beauclercq S, Hennequet-Antier C, Praud C, Godet E, et al.
📚 41 cit.🎯 RCR 2.42 - Reuma.pt contribution to the knowledge of immune-mediated systemic rheumatic diseases
Acta reumatologica portuguesa · 2017 · Journal Article
Santos MJ, Canhão H, Mourão AF, Oliveira Ramos F, et al.
📚 8 cit.🔬→🩺 Translationnel - Circulating miR-155, miR-145 and let-7c as diagnostic biomarkers of the coronary artery disease
Scientific reports · 2017 · Journal Article
Faccini J, Ruidavets JB, Cordelier P, Martins F, et al.
📚 117 cit.🎯 RCR 4.97🔬→🩺 Translationnel - Proceedings of the 3rd IPLeiria's International Health Congress : Leiria, Portugal. 6-7 May 2016
BMC health services research · 2016 · Journal Article
Tomás CC, Oliveira E, Sousa D, Uba-Chupel M, et al.
📚 343 cit.🎯 RCR 19.20🔬→🩺 Translationnel - Loss of Ovarian Function Results in Increased Loss of Skeletal Muscle in Arthritic Rats
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2016 · Journal Article
Furlanetto Júnior R, Martins FM, Oliveira AA, Nunes PR, et al.
📚 2 cit. - Salivary MicroRNA in Pancreatic Cancer Patients
PloS one · 2015 · Journal Article
Humeau M, Vignolle-Vidoni A, Sicard F, Martins F, et al.
📚 103 cit.🎯 RCR 3.91🔬→🩺 Translationnel
Lupus4
▼
Lupus4
▼- Systemic lupus erythematosus induced by anti-tumor necrosis factor α therapy in inflammatory rheumatic diseases: a case series
Reumatismo · 2024 · Journal Article
Oliveira D, Martins A, Martins F, Gomes C, et al.
📚 1 cit. - Severe and life-threatening onset of systemic lupus erythematosus
Reumatologia clinica · 2023 · Case Reports
Martins A, Pimenta S, Oliveira D, Martins F, et al.
📚 1 cit. - Factors associated with poor outcomes in SLE patients with COVID-19: Data from ReumaCoV-Brazil register
Lupus · 2023 · Journal Article
Carvalho JS, Dos Reis Neto ET, Kakehasi AM, Ribeiro SL, et al.
📚 4 cit. - Pseudo-pseudo Meigs syndrome: an uncommon onset of Systemic Lupus Erythematosus
ARP rheumatology · 2022 · Journal Article
Martins A, Pimenta S, Rato M, Oliveira D, et al.
📚 1 cit.
Anti-TNF3
▼
Anti-TNF3
▼- Effectiveness and safety of original and biosimilar etanercept (Enbrel® vs Benepali®) in bDMARD-naïve patients in a real-world cohort of Portugal
ARP rheumatology · 2022 · Journal Article
Pinto AS, Cunha MM, Pinheiro F, Bernardes M, et al.
📚 12 cit.🎯 RCR 1.43🩺 Clinique - GO-DACT: a phase 3b randomised, double-blind, placebo-controlled trial of GOlimumab plus methotrexate (MTX) versus placebo plus MTX in improving DACTylitis in MTX-naive patients with psoriatic arthritis
Annals of the rheumatic diseases · 2020 · Clinical Trial, Phase III
Vieira-Sousa E, Alves P, Rodrigues AM, Teixeira F, et al.
📚 45 cit.🎯 RCR 3.34🩺 Clinique - The GO-DACT protocol: a multicentre, randomized, double-blind, parallel-group study to compare the efficacy of golimumab in combination with methotrexate (MTX) versus MTX monotherapy
Acta reumatologica portuguesa · 2018 · Comparative Study
Vieira-Sousa E, Canhão H, Alves P, Rodrigues AM, et al.
📚 4 cit.🩺 Clinique
Case report / série2
▼
Case report / série2
▼- Anakinra and hepatotoxicity in pediatric rheumatology: a case series
Pediatric rheumatology online journal · 2023 · Case Reports
Martins FR, Azevedo AC, Ganhão S, Aguiar F, et al.
📚 3 cit. - A Rare Geriatric Diagnosis of Eosinophilic Granulomatosis With Polyangiitis: A Case Report
Cureus · 2023 · Case Reports
Emidio FC, Pereira RC, Martins FR, Marques RC, et al.
📚 2 cit.
csDMARDs2
▼
csDMARDs2
▼- GO-DACT: a phase 3b randomised, double-blind, placebo-controlled trial of GOlimumab plus methotrexate (MTX) versus placebo plus MTX in improving DACTylitis in MTX-naive patients with psoriatic arthritis
Annals of the rheumatic diseases · 2020 · Clinical Trial, Phase III
Vieira-Sousa E, Alves P, Rodrigues AM, Teixeira F, et al.
📚 45 cit.🎯 RCR 3.34🩺 Clinique - The GO-DACT protocol: a multicentre, randomized, double-blind, parallel-group study to compare the efficacy of golimumab in combination with methotrexate (MTX) versus MTX monotherapy
Acta reumatologica portuguesa · 2018 · Comparative Study
Vieira-Sousa E, Canhão H, Alves P, Rodrigues AM, et al.
📚 4 cit.🩺 Clinique
Épidémiologie & registres2
▼
Épidémiologie & registres2
▼- Systemic Vasculitides in Portugal and Brazil: A Binational, Cross-sectional, Multicentre Study From Reuma.pt/vasculitis Registry
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2026 · Journal Article
de Aguiar MF, Martins-Martinho J, Carones A, Bacchiega ABS, et al.
- Reuma.pt/vasculitis - the Portuguese vasculitis registry
Orphanet journal of rare diseases · 2020 · Journal Article
Ponte C, Khmelinskii N, Teixeira V, Luz K, et al.
📚 11 cit.
Arthrite juvénile1
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Arthrite juvénile1
▼- Effectiveness and long-term retention of anti-tumour necrosis factor treatment in juvenile and adult patients with juvenile idiopathic arthritis: data from Reuma.pt
Rheumatology (Oxford, England) · 2016 · Journal Article
Mourão AF, Santos MJ, Melo Gomes JA, Martins FM, et al.
📚 21 cit.🎯 RCR 1.06🩺 Clinique
Essai clinique1
▼
Essai clinique1
▼- Acute Whole-Body Vibration Exercise Promotes Favorable Handgrip Neuromuscular Modifications in Rheumatoid Arthritis: A Cross-Over Randomized Clinical
BioMed research international · 2021 · Journal Article
Coelho-Oliveira AC, Lacerda ACR, de Souza ALC, Santos LMM, et al.
📚 6 cit.🩺 Clinique
Génétique1
▼
Génétique1
▼- Genetic diversity, linkage disequilibrium and power of a large grapevine (Vitis vinifera L) diversity panel newly designed for association studies
BMC plant biology · 2016 · Journal Article
Nicolas SD, Péros JP, Lacombe T, Launay A, et al.
📚 56 cit.🎯 RCR 2.50
Gériatrie1
▼
Gériatrie1
▼- A Rare Geriatric Diagnosis of Eosinophilic Granulomatosis With Polyangiitis: A Case Report
Cureus · 2023 · Case Reports
Emidio FC, Pereira RC, Martins FR, Marques RC, et al.
📚 2 cit.
Goutte1
▼
Goutte1
▼- Dietary fiber and the short-chain fatty acid acetate promote resolution of neutrophilic inflammation in a model of gout in mice
Journal of leukocyte biology · 2017 · Journal Article
Vieira AT, Galvão I, Macia LM, Sernaglia ÉM, et al.
📚 119 cit.🎯 RCR 4.64🔬→🩺 Translationnel
Pédiatrie1
▼
Pédiatrie1
▼- Anakinra and hepatotoxicity in pediatric rheumatology: a case series
Pediatric rheumatology online journal · 2023 · Case Reports
Martins FR, Azevedo AC, Ganhão S, Aguiar F, et al.
📚 3 cit.
SAPL1
▼
SAPL1
▼- Evaluation of Frequency, Clinical Correlation, and Antibodies Confirmation Profile in Patients with Suspected Antiphospholipid Syndrome
TH open : companion journal to thrombosis and haemostasis · 2021 · Journal Article
Martins FF, Campos TML
📚 6 cit.
Sjögren1
▼
Sjögren1
▼- Diagnostic accuracy of ultrasonography in relation to salivary gland biopsy in Sjögren's syndrome: a systematic review with meta-analysis
Dento maxillo facial radiology · 2024 · Meta-Analysis
Martins FB, Oliveira MB, Oliveira LM, Lourenço AG, et al.
📚 5 cit.🎯 RCR 1.67
