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Rhumatologue

Docteur MARINE FORIEN

📍 Paris 18e Arrondissement (75)HospitalierRPPS 10100809481
📊 Reconnaissance scientifique : 15/100📝 98 articles publiés📚 HAL (8)

Diplômes

🎓 DES & spécialité ordinale

  • DES Rhumatologie
  • Rhumatologie (SM)

🎓 Diplômes

  • DE Docteur en médecine

Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.

Activité de recherche & publications

Source : bases de données publiques (OpenAlex, PubMed).

h-index

15

h articles cités ≥ h fois chacun. Un h de 15 = 15 publications avec 15+ citations.

Citations

763

Publications

98

i10-index

19

Thématiques principales

  • Rheumatoid Arthritis Research and Therapies ×23
  • Gout, Hyperuricemia, Uric Acid ×17
  • Spondyloarthritis Studies and Treatments ×16
  • Bone and Joint Diseases ×13
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis ×11

Affiliations FR : Assistance Publique – Hôpitaux de Paris · Hôpital Bichat-Claude-Bernard

Voir sur OpenAlex ↗🆔 ORCID 0000-0003-1375-2044

Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.

Bibliographie

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Lieu de consultation

  • GHU APHP NUP SITE BICHAT C BERNARD

    46 Rue HENRI HUCHARD, 75877 Paris 18e Arrondissement

    ☎ 0140258080Hospitalier

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

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Prendre rendez-vous & contact

🗓 Trouver sur Doctolib📇 Ajouter à mes contacts

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

  • 1
    Body mass index influences the response to infliximab in ankylosing spondylitis

    Arthritis research & therapy · 2012

    📚 84 citations🎯 RCR 2.94Top 17% NIH🔓 Open Access📄 PDF gratuit ↗
    Lire l'abstract Crossref ↓

    Abstract Introduction The excess of adipose tissue in obese individuals may have immunomodulating properties and pharmacokinetic consequences. The aim of this study was to determine whether body mass index (BMI) affects response to infliximab (IFX) in ankylosing spondylitis (AS) patients. Methods In 155 patients retrospectively included with active AS, the BMI was calculated before initiation of IFX treatment (5 mg/kg intravenously). After 6 months of treatment, changes from baseline in BASDAI, Visual Analogue Scale (VAS) pain, C-reactive protein (CRP) level, and total dose of nonsteroidal antiinflammatory drug (NSAID) were dichotomized with a threshold corresponding to a decrease of 50% of initial level of the measure, into binary variables assessing response to IFX (BASDAI50, VAS50, CRP50, NSAID50). Whether the BMI was predictive of the response to IFX therapy according to these definitions was assessed with logistic regression. Results Multivariate analysis found that a higher BMI was associated with a lower response for BASDAI50 (P = 0.0003; OR, 0.87; 95% CI (0.81 to 0.94)), VAS50 (P < 0.0001; OR, 0.87; 95% CI (0.80 to 0.93)); CRP50 (P = 0.0279; OR, 0.93; 95% CI (0.88 to 0.99)), and NSAID50 (P = 0.0077; OR, 0.91; 95% CI (0.85 to 0.97)), criteria. According to the three WHO BMI categories, similar results were found for BASDAI50 (77.6%, 48.9%, and 26.5%; P < 0.0001), VAS50 (72.6%, 40.4%, and 16.7%; P < 0.0001); CRP50 (87.5%, 65.7%, and 38.5%; P = 0.0001), and NSAID50 (63.2%, 51.5%, and 34.6%; P = 0.06). Conclusions This study provides the first evidence that a high BMI negatively influences the response to IFX in AS. Further prospective studies, including assessment of the fat mass, pharmacokinetics, and adipokines dosages are mandatory to elucidate the role of obesity in AS IFX response.

  • 2
    Predictors of hypogammaglobulinemia during rituximab maintenance therapy in rheumatoid arthritis: A 12-year longitudinal multi-center study

    Seminars in arthritis and rheumatism · 2018

    📚 61 citations🎯 RCR 2.64Top 19% NIH
  • 3
    Ectopic Germinal Center-Like Structures in Minor Salivary Gland Biopsy Tissue Predict Lymphoma Occurrence in Patients With Primary Sjögren's Syndrome

    Arthritis & rheumatology (Hoboken, N.J.) · 2018

    📚 57 citations🎯 RCR 2.58Top 20% NIH
    Lire l'abstract Crossref ↓

    ObjectiveTo determine risk factors for primary Sjögren's syndrome (SS)–associated lymphoma in a multicenter cohort of patients, with analysis of the predictive power of previously reported risk factors, including the presence of ectopic germinal center (GC)–like structures in minor salivary gland (MSG) biopsy tissue.MethodsOne hundred fifteen patients with primary SS were included, and MSG biopsy tissue from these patients was retrospectively examined, focusing on the presence of ectopic GC‐like structures. Epidemiologic, clinical, biologic, immunologic, and histologic data were collected at the time of diagnosis of primary SS. Patients with non‐Hodgkin's lymphoma (NHL) were compared with those without NHL during the follow‐up period, using a Cox proportional hazards multiple regression model.ResultsNHL was diagnosed in 8 patients (6.96%), and ectopic GC‐like structures in 19 patients (16.5%). The presence of ectopic GC‐like structures was associated with a 7.8‐fold increased risk of lymphoma occurrence (95% confidence interval [95% CI] 1.73–34.86 [P = 0.0075]). Other independent predictors included a positive cryoglobulin test result (hazard ratio [HR] 7.10, 95% CI 1.74–28.92 [P = 0.006]), male sex (HR 28.73, 95% CI 4.46–144.87 [P = 0.0004]), sensorimotor neuropathy (HR 35.48, 95% CI 5.79–217.39 [P = 0.0001]), and splenomegaly (HR 19.9, 95% CI 4.4–90 [P = 0.0001]).ConclusionThe presence of ectopic GC‐like structures in MSG biopsy tissue is associated with the risk of lymphoma in patients with primary SS. These data reinforce the major role of MSG biopsy tissue in primary SS, for the identification a priori of a subgroup of patients with the highest risk of lymphoma.

Publications scientifiques (48) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Transversal31

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Goutte5

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Biothérapies non-anti-TNF3

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Case report / série2

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Anti-TNF1

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Corticothérapie1

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CPPD1

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Économie santé1

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Sjögren1

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Spondyloarthrite1

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Vraie vie / RWE1

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