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Rhumatologue

Docteur VALERIE DEVAUCHELLE

📍 Brest (29)HospitalierRPPS 10003490199
📊 Reconnaissance scientifique : 57/100📝 509 articles publiés📚 HAL (8)

✨ Profil synthétique

IA · 30/04/2026

Le Docteur Valérie Devauchelle est un rhumatologue hospitalier à Brest, avec une production scientifique importante dans le domaine de la rhumatologie. Ses recherches portent principalement sur les maladies auto-immunes, notamment le lupus, la sclérodermie et la maladie de Sjögren. Avec un h-index de 57 et plus de 509 publications, elle est une figure marquante dans son domaine.

Expertises présumées

  • Sjögren
  • Lupus
  • Sclérodermie
  • Arthrite juvénile
  • Biothérapies non-anti-TNF
  • Thérapies anti-TNF
  • Épidémiologie des maladies rhumatismales

Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.

Diplômes

🎓 DES & spécialité ordinale

  • DES Rhumatologie
  • Rhumatologie (SM)

🎓 Diplômes

  • DE Docteur en médecine

Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.

Activité de recherche & publications

Source : bases de données publiques (OpenAlex, PubMed).

h-index

57

h articles cités ≥ h fois chacun. Un h de 57 = 57 publications avec 57+ citations.

Citations

10 408

Publications

509

i10-index

166

Thématiques principales

  • Salivary Gland Disorders and Functions ×240
  • Rheumatoid Arthritis Research and Therapies ×105
  • Systemic Lupus Erythematosus Research ×78
  • Salivary Gland Tumors Diagnosis and Treatment ×76
  • Systemic Sclerosis and Related Diseases ×66

Affiliations FR : Centre Hospitalier Régional Universitaire de Brest

Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.

Bibliographie

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Localisation

Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.

Lieux de consultation

  • UNIVERSITE BREST BRETAGNE OCCIDENTALE

    UNIVERSITE BREST BRETAGNE OCCIDENTALE — 13 RUE LANREDEC, 29200 Brest

    Hospitalier
  • CHRU BREST SITE HOPITAL CAVALE BLANCHE

    Boulevard TANGUY PRIGENT, 29609 Brest

    0298223333Hospitalier

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Articles de presse (10)

Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).

Top publications · les plus citées

  • 2
    EULAR Sjögren's syndrome disease activity index (ESSDAI): a user guide

    RMD open · 2015

    📚 278 citations🎯 RCR 11.92Top 2% NIH🔓 Open Access📄 PDF gratuit ↗
    Lire l'abstract Crossref ↓

    The EULAR Sjögren's syndrome (SS) disease activity index (ESSDAI) is a systemic disease activity index that was designed to measure disease activity in patients with primary SS. With the growing use of the ESSDAI, some domains appear to be more challenging to rate than others. The ESSDAI is now in use as a gold standard to measure disease activity in clinical studies, and as an outcome measure, even a primary outcome measure, in current randomised clinical trials. Therefore, ensuring an accurate and reproducible rating of each domain, by providing a more detailed definition of each domain, has emerged as an urgent need. The purpose of the present article is to provide a user guide for the ESSDAI. This guide provides definitions and precisions on the rating of each domain. It also includes some minor improvement of the score to integrate advance in knowledge of disease manifestations. This user guide may help clinicians to use the ESSDAI, and increase the reliability of rating and consequently of the ability to detect true changes over time. This better appraisal of ESSDAI items, along with the recent definition of disease activity levels and minimal clinically important change, will improve the assessment of patients with primary SS and facilitate the demonstration of effectiveness of treatment for patients with primary SS.

  • 3
    BAFF overexpression is associated with autoantibody production in autoimmune diseases

    Annals of the New York Academy of Sciences · 2005

    📚 263 citations🎯 RCR 5.48Top 7% NIH
    Lire l'abstract Crossref ↓

    Abstract: The B‐cell activity factor (BAFF) acts as a positive regulator of B‐cell function. To gain further insight into the understanding of B‐cell hyperactivity in autoimmune diseases, the serum level of BAFF was determined in 43 systemic lupus erythematosus (SLE) patients, 58 primary Sjögren's syndrome (pSS) patients, 28 rheumatoid arthritis (RA) patients, and 68 normal control subjects using an in‐house sandwich ELISA. A commercial kit was used to detect soluble CD23 (sCD23) reflecting B‐cell activation. In‐house assays for the detection of autoantibodies also were used. We found an increased level of BAFF in SLE, pSS, and RA sera compared with normal subjects (respectively, 10.6 ± 8.5, 15.8 ± 12.9, 9.7 ± 1.5 ng/mL vs. 4.6 ± 2.9/ng/mL, P < .001). sCD23 released on B‐cell activation also was found to be elevated in SLE, pSS, and RA compared with normal sera. However, no correlation was found between the circulating BAFF and the level of sCD23. By contrast, we observed that high levels of BAFF were associated with the presence of autoantibodies (anti‐double‐stranded DNA antibodies in SLE, anti‐SSA antibodies in pSS, and rheumatoid factors in RA). Our data suggest that BAFF is influential in driving antibody production rather than activation of the B lymphocytes in autoimmune diseases.

Publications scientifiques (50) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Transversal21

Sjögren20

Biothérapies non-anti-TNF4

Anti-TNF2

Arthrite juvénile2

Épidémiologie & registres1

Lupus1

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