Docteur CHRISTELLE DARRIEUTORT-LAFFITE
7ans d'exercice (thèse 2019)
✨ Profil synthétique
IA · 29/04/2026Le Docteur Christelle DARRIEUTORT-LAFFITE est une rhumatologue hospitalière à Nantes, avec une production scientifique significative dans le domaine de la rhumatologie. Ses recherches portent principalement sur les tendinopathies, les pathologies du rachis et les spondylarthropathies. Avec un h-index de 17 et 112 publications, elle a également dirigé des thèses dans le domaine de la biologie cellulaire et du développement.
Expertises présumées
- Tendinopathies
- Pathologies du rachis
- Spondylarthropathies
- Lombalgie
- Ostéoporose
- Corticothérapie
- Essais cliniques
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- DES Rhumatologie
- Rhumatologie (SM)
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Thèses universitaires
Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.
Direction de thèses
🎓 1 thèse dirigéeSource theses.fr — signal de direction d'équipe / statut PU-PH (à confirmer via le site universitaire).
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
17
h articles cités ≥ h fois chacun. Un h de 17 = 17 publications avec 17+ citations.
Citations
795
Publications
112
i10-index
27
Thématiques principales
- Shoulder Injury and Treatment ×40
- Tendon Structure and Treatment ×21
- Spine and Intervertebral Disc Pathology ×17
- Orthopedic Infections and Treatments ×15
- Spondyloarthritis Studies and Treatments ×13
Affiliations FR : Inserm · Oniris · Nantes Université
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Pyomyositis of the obturator internus muscle
2025ArticleJoint Bone Spine
Musculoskeletal disorders affecting upper and lower limbs in pregnant women: How to manage them?
2025ArticleRevue du Rhumatisme
Septic pubic Symphysitis: newest radiological, microbiological and outcome findings in a rare and difficult-to-treat infection
2025ArticleClinical Microbiology and Infection
Indications and contraindications to platelet‐rich plasma injections in musculoskeletal diseases in case of infectious, oncological and haematological comorbidities: A 2025 formal consensus from the GRIIP (International Research Group on Platelet Injections)
2025ArticleKnee Surgery, Sports Traumatology, Arthroscopy
How should shoulder tendinopathy be managed according to French Health Authority recommendations?
2025ArticleRevue du Rhumatisme
Decorin Knockdown Improves Aged Tendon Healing by Enhancing Recovery of Viscoelastic Properties, While Biglycan May Not
2025ArticleAnnals of Biomedical Engineering
Are handheld dynamometers a valid alternative to isokinetic devices for assessing the shoulder rotators in neurogenic thoracic outlet syndrome?
2025ArticleAnnals of Physical and Rehabilitation Medicine
Tendon-targeted knockout of collagen XI disrupts patellar and Achilles tendon structure and mechanical properties during murine postnatal development
2024ArticleConnective Tissue Research
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Lieu de consultation
CHU DE NANTES SITE HOTEL DIEU HME
1 Place ALEXIS RICORDEAU, 44093 Nantes
Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 1Calcific tendonitis of the rotator cuff: From formation to resorption
Joint bone spine · 2018
📚 46 citations🎯 RCR 2.87Top 17% NIH - 2IL-1β and TNFα promote monocyte viability through the induction of GM-CSF expression by rheumatoid arthritis synovial fibroblasts
Mediators of inflammation · 2014
Lire l'abstract Crossref ↓
Background. Macrophages and synovial fibroblasts (SF) are two major cells implicated in the pathogenesis of rheumatoid arthritis (RA). SF could be a source of cytokines and growth factors driving macrophages survival and activation. Here, we studied the effect of SF on monocyte viability and phenotype.Methods. SF were isolated from synovial tissue of RA patients and CD14+ cells were isolated from peripheral blood of healthy donors. SF conditioned media were collected after 24 hours of culture with or without stimulation with TNFαor IL-1β. Macrophages polarisation was studied by flow cytometry.Results. Conditioned medium from SF significantly increased monocytes viability by 60% compared to CD14+ cells cultured in medium alone(P<0.001). This effect was enhanced using conditioned media from IL-1βand TNFαstimulated SF. GM-CSF but not M-CSF nor IL34 blocking antibodies was able to significantly decrease monocyte viability by 30% when added to the conditioned media from IL-1βand TNFαstimulated SF(P<0.001). Finally, monocyte cultured in presence of SF conditioned media did not exhibit a specific M1 or M2 phenotype.Conclusion. Overall, rheumatoid arthritis synovial fibroblasts stimulated with proinflammatory cytokines (IL-1βand TNFα) promote monocyte viability via GM-CSF but do not induce a specific macrophage polarization.
- 3Biology and physiology of tendon healing
Joint bone spine · 2024
📚 43 citations🎯 RCR 13.88Top 1% NIH🔓 Open Access
Publications scientifiques (47) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal32
▼
Transversal32
▼- Are handheld dynamometers a valid alternative to isokinetic devices for assessing the shoulder rotators in neurogenic thoracic outlet syndrome?
Annals of physical and rehabilitation medicine · 2025 · Letter
Mercier EL, Darrieutort-Laffite C, Goff BL, Pomares G, et al.
📚 1 cit. - Decorin Knockdown Improves Aged Tendon Healing by Enhancing Recovery of Viscoelastic Properties, While Biglycan May Not
Annals of biomedical engineering · 2025 · Journal Article
Darrieutort-Laffite C, Weiss SN, Nuss CA, Newton JB, et al.
📚 2 cit. - [Tendinopathies associated with the use of quinolones]
La Revue de medecine interne · 2025 · Journal Article
Robin A, Kouki I, Darrieutort-Laffite C, Richier Q
- Pyomyositis of the obturator internus muscle
Joint bone spine · 2025 · Journal Article
Renaud T, Le Pluart A, Arnolfo P, Darrieutort-Laffite C
- Septic pubic symphysitis: newest radiological, microbiological, and outcome findings in a rare and difficult-to-treat infection
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2025 · Letter
Tabary S, Robin F, Darrieutort-Laffite C, Lautredoux F, et al.
- 2023 French recommendations for diagnosing and managing prepatellar and olecranon septic bursitis
Joint bone spine · 2024 · Review
Darrieutort-Laffite C, Coiffier G, Aïm F, Banal F, et al.
- Tendon-targeted knockout of collagen XI disrupts patellar and Achilles tendon structure and mechanical properties during murine postnatal development
Connective tissue research · 2024 · Journal Article
Cohen JS, Fung AK, Stein MK, Darrieutort-Laffite C, et al.
📚 3 cit. - Biology and physiology of tendon healing
Joint bone spine · 2024 · Journal Article
Darrieutort-Laffite C, Blanchard F, Soslowsky LJ, Le Goff B
📚 43 cit.🎯 RCR 13.88 - Knockdown of biglycan reveals an important role in maintenance of structural and mechanical properties during tendon aging
Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023 · Journal Article
Darrieutort-Laffite C, Beach ZM, Weiss SN, Eekhoff JD, et al.
📚 9 cit.🎯 RCR 1.95 - Association between radiographic and functional outcome in vertebral osteomyelitis SPONDIMMO, a 6-month prospective multicenter cohort
Joint bone spine · 2023 · Multicenter Study
Chevalerias M, Coiffier G, Darrieutort-Laffite C, Godot S, et al.
- Transient flares (attacks) of inflammatory arthritis should be more considered
Joint bone spine · 2023 · Editorial
Berthelot JM, Darrieutort-Laffite C
📚 1 cit. - Contribution of HLA DRB1, PTPN22, and CTLA4, to RA dysbiosis
Joint bone spine · 2022 · Review
Berthelot JM, Darrieutort-Laffite C, Le Goff B
📚 5 cit. - Venous congestion as a central mechanism of radiculopathies
Joint bone spine · 2022 · Journal Article
Berthelot JM, Douane F, Ploteau S, Le Goff B, et al.
📚 10 cit.🎯 RCR 1.13🔬→🩺 Translationnel - Management and outcome of native joint septic arthritis: a nationwide survey in French rheumatology departments, 2016-2017
Annals of the rheumatic diseases · 2022 · Journal Article
Richebé P, Coiffier G, Guggenbuhl P, Mulleman D, et al.
📚 7 cit. - Contribution of mycobiota to the pathogenesis of spondyloarthritis
Joint bone spine · 2021 · Journal Article
Berthelot JM, Darrieutort-Laffite C, Trang C, Maugars Y, et al.
📚 11 cit. - Clinical characteristics and management of olecranon and prepatellar septic bursitis in a multicentre study
The Journal of antimicrobial chemotherapy · 2021 · Journal Article
Charret L, Bart G, Hoppe E, Dernis E, et al.
📚 7 cit.🩺 Clinique - Fibromyalgia and Associated Disorders: From Pain to Chronic Suffering, From Subjective Hypersensitivity to Hypersensitivity Syndrome
Frontiers in medicine · 2021 · Journal Article
Maugars Y, Berthelot JM, Le Goff B, Darrieutort-Laffite C
📚 30 cit.🎯 RCR 3.05🔬→🩺 Translationnel - Pro-inflammatory effects of human apatite crystals extracted from patients suffering from calcific tendinopathy
Arthritis research & therapy · 2021 · Journal Article
Herman J, Le Goff B, De Lima J, Brion R, et al.
📚 14 cit.🎯 RCR 1.05🔬→🩺 Translationnel - Inadequacies of the Lasègue test, and how the Slump and Bowstring tests are useful for the diagnosis of sciatica
Joint bone spine · 2021 · Journal Article
Berthelot JM, Darrieutort-Laffite C, Arnolfo P, Glémarec J, et al.
📚 6 cit. - Is ultrasound-guided caudal steroid injection effective in the management of lower lumbar radicular pain? A two-center prospective observational study on 150 patients
Joint bone spine · 2020 · Letter
Robin F, Coiffier G, Albert JD, Darrieutort-Laffite C, et al.
📚 1 cit.🩺 Clinique - 2020 French recommendations on the management of septic arthritis in an adult native joint
Joint bone spine · 2020 · Journal Article
Couderc M, Bart G, Coiffier G, Godot S, et al.
📚 41 cit.🎯 RCR 3.33🔬→🩺 Translationnel - Rheumatic involvement and bone scan features in Schnitzler syndrome: initial and follow-up data from a single-center cohort of 25 patients
Arthritis research & therapy · 2020 · Journal Article
Darrieutort-Laffite C, Ansquer C, Aubert H, Kraeber-Bodéré F, et al.
📚 6 cit.🔬→🩺 Translationnel - Is it currently reasonable to offer short, 14-day antibiotic therapies after a surgical synovectomy in native joint septic arthritis?
Annals of the rheumatic diseases · 2020 · Letter
Coiffier G, Couderc M, Seror R, Bart G, et al.
📚 2 cit. - Molecular and Structural Effects of Percutaneous Interventions in Chronic Achilles Tendinopathy
International journal of molecular sciences · 2020 · Journal Article
Darrieutort-Laffite C, Soslowsky LJ, Le Goff B
📚 16 cit.🎯 RCR 1.50 - Are painDETECT scores in musculoskeletal disorders associated with duration of daily pain and time elapsed since current pain onset?
Pain reports · 2019 · Journal Article
Berthelot JM, Biha N, Darrieutort-Laffite C, Le Goff B, et al.
📚 9 cit. - Stretching of roots contributes to the pathophysiology of radiculopathies
Joint bone spine · 2018 · Journal Article
Berthelot JM, Laredo JD, Darrieutort-Laffite C, Maugars Y
📚 10 cit.🔬→🩺 Translationnel - Detection of a lumbar foraminal venous varix by Color Doppler Ultrasound
Joint bone spine · 2016 · Case Reports
Darrieutort-Laffite C, Desal H, Berthelot JM, Le Goff B
- Sodium (18)F-sodium fluoride PET failed to predict responses to TNFα antagonist therapy in 31 patients with possible spondyloarthritis not meeting ASAS criteria
Joint bone spine · 2015 · Journal Article
Darrieutort-Laffite C, Ansquer C, Maugars Y, Le Goff B, et al.
📚 8 cit. - Ultrasonography of the lumbar spine: sonoanatomy and practical applications
Joint bone spine · 2014 · Journal Article
Darrieutort-Laffite C, Hamel O, Glémarec J, Maugars Y, et al.
📚 26 cit.🎯 RCR 1.63🔬→🩺 Translationnel - IL-1β and TNFα promote monocyte viability through the induction of GM-CSF expression by rheumatoid arthritis synovial fibroblasts
Mediators of inflammation · 2014 · Journal Article
Darrieutort-Laffite C, Boutet MA, Chatelais M, Brion R, et al.
📚 46 cit.🎯 RCR 1.29 - [Staphylococcus caprae arthritis]
Medecine et maladies infectieuses · 2013 · Case Reports
Darrieutort-Laffite C, André V, Leautez S, Tanguy G, et al.
📚 5 cit. - Candida albicans diskitis after body piercing in an immunocompetent patient
Joint bone spine · 2013 · Case Reports
Darrieutort-Laffite C, Lassalle C, Chouet-Girard F, Perez L, et al.
📚 2 cit.
Tendinopathies & SCC6
▼
Tendinopathies & SCC6
▼- A prospective study of 100 patients with rotator cuff tendinopathy showed no correlation between subacromial bursitis and the efficacy of ultrasound-guided corticosteroid injection
European radiology · 2024 · Journal Article
Metayer B, Fouasson-Chailloux A, Le Goff B, Darrieutort-Laffite C
- Development of a new radiographic score for the follow-up of calcific tendinopathy of the rotator cuff
Clinical and experimental rheumatology · 2024 · Journal Article
Dalla-Torre R, Fouasson-Chailloux A, Le Goff B, Darrieutort-Laffite C
- Factors Associated With Clinical Improvement and the Disappearance of Calcifications After Ultrasound-Guided Percutaneous Lavage of Rotator Cuff Calcific Tendinopathy: A Post Hoc Analysis of a Randomized Controlled Trial
The American journal of sports medicine · 2021 · Journal Article
Dumoulin N, Cormier G, Varin S, Coiffier G, et al.
📚 10 cit.🎯 RCR 1.29🩺 Clinique - Location of calcifications of rotator cuff on ultrasound in 74 patients: Near the junction between the supraspinatus and infraspinatus tendons in 96% of the cases
Joint bone spine · 2021 · Letter
Sougué C, Darrieutort-Laffite C, Maugars Y, Le Goff B
📚 1 cit. - Rotator Cuff Tenocytes Differentiate into Hypertrophic Chondrocyte-Like Cells to Produce Calcium Deposits in an Alkaline Phosphatase-Dependent Manner
Journal of clinical medicine · 2019 · Journal Article
Darrieutort-Laffite C, Arnolfo P, Garraud T, Adrait A, et al.
📚 16 cit.🎯 RCR 1.07 - Calcific tendonitis of the rotator cuff: From formation to resorption
Joint bone spine · 2018 · Journal Article
Darrieutort-Laffite C, Blanchard F, Le Goff B
📚 46 cit.🎯 RCR 2.87🔬→🩺 Translationnel
Essai clinique2
▼
Essai clinique2
▼- Are corticosteroid injections needed after needling and lavage of calcific tendinitis? Randomised, double-blind, non-inferiority trial
Annals of the rheumatic diseases · 2019 · Journal Article
Darrieutort-Laffite C, Varin S, Coiffier G, Albert JD, et al.
📚 16 cit.🎯 RCR 1.58🩺 Clinique - Usefulness of a pre-procedure ultrasound scanning of the lumbar spine before epidural injection in patients with a presumed difficult puncture: A randomized controlled trial
Joint bone spine · 2015 · Journal Article
Darrieutort-Laffite C, Bart G, Planche L, Glemarec J, et al.
📚 11 cit.🩺 Clinique
Ostéoporose2
▼
Ostéoporose2
▼- Long-term follow up after denosumab treatment for osteoporosis - rebound associated with hypercalcemia, parathyroid hyperplasia, severe bone mineral density loss, and multiple fractures: a case report
Journal of medical case reports · 2020 · Case Reports
Maugars Y, Guillot P, Glémarec J, Berthelot JM, et al.
📚 10 cit. - Multiple Vertebral Osteonecroses (Kümmell's Disease) After 10 Years on Denosumab: Is Osteocyte Apoptosis to Blame?
Calcified tissue international · 2018 · Journal Article
Maugars Y, Bart G, Guillot P, Chemel-Mary M, et al.
📚 7 cit.🔬→🩺 Translationnel
Corticothérapie1
▼
Corticothérapie1
▼- Are corticosteroid injections needed after needling and lavage of calcific tendinitis? Randomised, double-blind, non-inferiority trial
Annals of the rheumatic diseases · 2019 · Journal Article
Darrieutort-Laffite C, Varin S, Coiffier G, Albert JD, et al.
📚 16 cit.🎯 RCR 1.58🩺 Clinique
Lombalgie1
▼
Lombalgie1
▼- Efficacy of local glucocorticoid after local anesthetic in low back pain with lumbosacral transitional vertebra: A randomized placebo-controlled double-blind trial
Joint bone spine · 2018 · Journal Article
Glémarec J, Varin S, Cozic C, Tanguy G, et al.
📚 8 cit.🩺 Clinique
Recommandations1
▼
Recommandations1
▼- Indications and contraindications to platelet-rich plasma injections in musculoskeletal diseases in case of infectious, oncological and haematological comorbidities: A 2025 formal consensus from the GRIIP (International Research Group on Platelet Injections)
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025 · Consensus Statement
Eymard F, Louati K, Noel É, Abouqal R, et al.
📚 9 cit.🎯 RCR 4.14
Revue générale1
▼
Revue générale1
▼- Update on contribution of hip labral tears to hip pain: A narrative review
Joint bone spine · 2023 · Review
Berthelot JM, Brulefert K, Arnolfo P, Le Goff B, et al.
📚 7 cit.🎯 RCR 2.29
Sjögren1
▼
Sjögren1
▼- Sjögren's syndrome complicated by interstitial cystitis: A case series and literature review
Joint bone spine · 2015 · Case Reports
Darrieutort-Laffite C, André V, Hayem G, Saraux A, et al.
📚 16 cit.🔬→🩺 Translationnel
Vraie vie / RWE1
▼
Vraie vie / RWE1
▼- Usefulness of real-world patient cohort follow-ups using questionnaires to assess the effect of treatments on the general population
Joint bone spine · 2021 · Editorial
Berthelot JM, Darrieutort-Laffite C, Le Goff B
📚 1 cit.
Datasets & protocoles partagés
Rheumatic involvement and bone scan features in Schnitzler syndrome: initial and follow-up data from a single-center cohort of 25 patients
Collection2020figshareAbstract Objective To report on the characteristics and long-term course of rheumatic manifestations in Schnitzler syndrome (SchS). Methods A retrospective cohort study of patients with SchS followed between 2000 and 202
Factors Associated With Clinical Improvement and the Disappearance of Calcifications After Ultrasound-Guided Percutaneous Lavage of Rotator Cuff Calcific Tendinopathy: A Post Hoc Analysis of a Randomized Controlled Trial
Collection2021SAGE JournalsBackground:Calcific tendinitis of the rotator cuff is a frequent cause of shoulder pain. Ultrasound-guided percutaneous lavage (UGPL) is an effective treatment, but factors associated with good clinical and radiological
Factors Associated With Clinical Improvement and the Disappearance of Calcifications After Ultrasound-Guided Percutaneous Lavage of Rotator Cuff Calcific Tendinopathy: A Post Hoc Analysis of a Randomized Controlled Trial
Collection2021SAGE JournalsBackground:Calcific tendinitis of the rotator cuff is a frequent cause of shoulder pain. Ultrasound-guided percutaneous lavage (UGPL) is an effective treatment, but factors associated with good clinical and radiological
Pro-inflammatory effects of human apatite crystals extracted from patients suffering from calcific tendinopathy
Collection2021figshareAbstract Background Calcific tendonitis of the rotator cuff is due to carbonated apatite deposits in the shoulder tendons. During the evolution of the disease, an acute inflammatory episode may occur leading to the disap
Rheumatic involvement and bone scan features in Schnitzler syndrome: initial and follow-up data from a single-center cohort of 25 patients
Collection2020figshareAbstract Objective To report on the characteristics and long-term course of rheumatic manifestations in Schnitzler syndrome (SchS). Methods A retrospective cohort study of patients with SchS followed between 2000 and 202
Pro-inflammatory effects of human apatite crystals extracted from patients suffering from calcific tendinopathy
Collection2021figshareAbstract Background Calcific tendonitis of the rotator cuff is due to carbonated apatite deposits in the shoulder tendons. During the evolution of the disease, an acute inflammatory episode may occur leading to the disap
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).
