Docteur HELENE CHE
✨ Profil synthétique
IA · 04/05/2026Le Docteur HELENE CHE est un rhumatologue hospitalier à Montpellier, titulaire de plusieurs diplômes universitaires validés, notamment en pathologies osseuses et en évaluation et prise en charge des maladies rhumatismales. Ses recherches portent principalement sur les maladies rhumatismales, notamment la polyarthrite rhumatoïde, la spondylarthrite et le lupus érythémateux systémique. Avec un h-index de 4 et 9 publications, elle contribue activement à la littérature scientifique dans son domaine.
Expertises présumées
- Polyarthrite rhumatoïde
- Spondylarthrite
- Lupus érythémateux systémique
- Ostéoarthrose
- Pathologies osseuses
- Évaluation et prise en charge des maladies rhumatismales
- Génétique des maladies rhumatismales
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- DES Rhumatologie
- Rhumatologie (SM)
🏅 DU / DIU
- DIU Pathologies osseuses médicales
- DIU Etudes approfondies polyarthrites-maladies
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
4
h articles cités ≥ h fois chacun. Un h de 4 = 4 publications avec 4+ citations.
Citations
309
Publications
9
i10-index
4
Thématiques principales
- Rheumatoid Arthritis Research and Therapies ×6
- Spondyloarthritis Studies and Treatments ×4
- Systemic Lupus Erythematosus Research ×2
- Osteoarthritis Treatment and Mechanisms ×1
- Hepatitis C virus research ×1
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
PhosphoLipid transfer protein (PLTP) exerts a direct pro-inflammatory effect on rheumatoid arthritis (RA) fibroblasts-like-synoviocytes (FLS) independently of its lipid transfer activity
2018ArticlePLoS ONE
Performance of patient-reported outcomes in the assessment of rheumatoid arthritis disease activity:the experience of the ESPOIR cohort.
2016ArticleClinical and experimental rheumatology
Evaluation of collected outcome measures in axial spondyloarthritis in daily-care rheumatology settings: the experience of the RHEVER network.
2015ArticleClinical and experimental rheumatology
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Localisation
Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.
Lieu de consultation
CL CLEMENTVILLE MONTPELLIER
25 Rue DE CLEMENTVILLE, 34000 Montpellier
☎ 0467067000Hospitalier
Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Articles de presse (1)
Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).
- Ostéoporose : une filière régionale au CHU de Montpellier - Midi Libre
📰 Midi Libre · 15/01/2016
<a href="https://news.google.com/rss/articles/CBMiigFBVV95cUxPLVFjUWg1R1RvWmVDMjJ4T3E2VERsUmRtT1lWYVpWTE5JckJRdUZSNEt1ZEpHMWNuUzNnNkhmNEhEamFrcEstWDVuWnplX0xxU1dSdVlPTTZZUkJYdlA5OHJ1eTBnTWx5VHhoRlJKUl9uVUJpV0RmMVNCbzdrckJoRmVRX2dsYWh2SUE?oc=5" target="_blank">Ostéoporose : une filière régionale au C
Top publications · les plus citées
- 1Impaired quality of life in adults with X-linked hypophosphatemia and skeletal symptoms
European journal of endocrinology · 2016
Lire l'abstract Crossref ↓
ObjectiveAdults with X-linked hypophosphatemia (XLH) may suffer from skeletal symptoms leading to functional disability. No data on their quality of life (QoL) have been reported so far. Our objectives were to evaluate the QoL and its determinants in XLH adults.Patients and methodsWe conducted a prospective study in XLH adults, who consulted for musculoskeletal symptoms between 2013 and 2014. We assessed their QoL using HAQ, RAPID3 and SF36, and analysed the variables associated with low QoL. We compared their QoL to that of patients affected with axial spondyloarthritis (ax-SpA) (paired on age and gender), a rheumatologic disorder with a known low QoL.ResultsFifty-two XLH adults (37 women (71.1%); mean age 41.8±13.3 years) were included; 44 (84.6%) patients had an altered QoL. Increased age and presence of structural lesions were significantly associated with worse QoL (HAQ, RAPID3) (P<0.05). Presence of enthesopathies was significantly associated with worse RAPID3 (OR=4.45 (1.09–18.29), P=0.038). Treatment with phosphate supplements and vitamin D in XLH adults were significantly associated with a better SF36-mental component score (OR=0.14 (0.03–0.57), P=0.007 and OR=0.26 (0.07–0.98), P=0.047 respectively). QoL was significantly worse in XLH than in ax-SpA adults (VAS pain, SF36-PCS, RAPID3) (P<0.05).ConclusionOur study showed i) QoL of XLH adults is altered and significantly worse than that of ax-SpA patients (VAS pain, SF36-PCS and RAPID3), ii) structural lesions and especially enthesopathies are associated with a worse QoL and iii) treatment using phosphate supplements and/or vitamin D is associated with a better mental health score.
- 2Risk of fracture and low bone mineral density in adults with inflammatory bowel diseases. A systematic literature review with meta-analysis
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
📚 76 citations🎯 RCR 3.93Top 11% NIH - 3SIRT1, a promising regulator of bone homeostasis
Life sciences · 2021
📚 66 citations🎯 RCR 4.93Top 8% NIH
Publications scientifiques (20) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal12
▼
Transversal12
▼- A new 3-arylbenzofuran derivative EIE-2 reestablishes Treg-dependent tolerance in rheumatoid arthritis by targeting on Syk induced mTOR and PKCθ imbalance
Frontiers in immunology · 2025 · Journal Article
Li P, Yin X, Wen X, Li X, et al.
📚 2 cit. - Injectable microspheres filled with copper-containing bioactive glass improve articular cartilage healing by regulating inflammation and recruiting stem cells
Regenerative biomaterials · 2025 · Journal Article
Gao H, Ning E, Zhang X, Shao Z, et al.
📚 7 cit.🎯 RCR 2.07 - The effect of allyl isothiocyanate on chondrocyte phenotype is matrix stiffness-dependent: Possible involvement of TRPA1 activation
Frontiers in molecular biosciences · 2023 · Journal Article
Che H, Shao Z, Ding J, Gao H, et al.
📚 4 cit. - Folate ameliorates homocysteine-induced osteoblast dysfunction by reducing endoplasmic reticulum stress-activated PERK/ATF-4/CHOP pathway in MC3T3-E1 cells
Journal of bone and mineral metabolism · 2022 · Journal Article
Su S, Zhang D, Liu J, Zhao H, et al.
📚 12 cit.🎯 RCR 1.47 - Multiple Brown Tumors in Primary Hyperparathyroidism
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2021 · Journal Article
Facorat O, Fontaine C, Courtieu C, Trevillot V, et al.
📚 1 cit. - SIRT1, a promising regulator of bone homeostasis
Life sciences · 2021 · Journal Article
Chen Y, Zhou F, Liu H, Li J, et al.
📚 66 cit.🎯 RCR 4.93 - Deletion of p16 prevents estrogen deficiency-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence
American journal of translational research · 2020 · Journal Article
Li J, Karim MA, Che H, Geng Q, et al.
📚 31 cit.🎯 RCR 1.68 - miR-101-3p/Rap1b signal pathway plays a key role in osteoclast differentiation after treatment with bisphosphonates
BMB reports · 2019 · News
Li J, Li Y, Wang S, Che H, et al.
📚 10 cit. - Vertebral fractures cascade: potential causes and risk factors
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019 · Journal Article
Che H, Breuil V, Cortet B, Paccou J, et al.
📚 34 cit.🎯 RCR 2.36🩺 Clinique - PhosphoLipid transfer protein (PLTP) exerts a direct pro-inflammatory effect on rheumatoid arthritis (RA) fibroblasts-like-synoviocytes (FLS) independently of its lipid transfer activity
PloS one · 2018 · Journal Article
Audo R, Deckert V, Daien CI, Che H, et al.
📚 21 cit.🔬→🩺 Translationnel - Evaluation of collected outcome measures in axial spondyloarthritis in daily-care rheumatology settings: the experience of the RHEVER network
Clinical and experimental rheumatology · 2015 · Journal Article
Che H, Etcheto A, Dernis E, Nataf H, et al.
📚 17 cit.🔬→🩺 Translationnel - Reply to Talarico et al.'s comment: "Rate of serious infections in patients with rheumatoid arthritis receiving tumor necrosis factor (TNF)-alpha antagonist: a prospective observational study"
Joint bone spine · 2014 · Letter
Che H, Lukas C, Morel J, Combe B
Revue générale3
▼
Revue générale3
▼- A narrative review of positive regulation of NLRP3 inflammasome in rheumatoid arthritis
Annals of palliative medicine · 2021 · Journal Article
Zhuang Y, Wang H, Su J, Zhang J, et al.
📚 15 cit.🎯 RCR 1.06 - Risk of fracture and low bone mineral density in adults with inflammatory bowel diseases. A systematic literature review with meta-analysis
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018 · Journal Article
Szafors P, Che H, Barnetche T, Morel J, et al.
📚 76 cit.🎯 RCR 3.93🔬→🩺 Translationnel - Risk of herpes/herpes zoster during anti-tumor necrosis factor therapy in patients with rheumatoid arthritis. Systematic review and meta-analysis
Joint bone spine · 2014 · Journal Article
Che H, Lukas C, Morel J, Combe B
📚 63 cit.🎯 RCR 2.45🔬→🩺 Translationnel
Génétique2
▼
Génétique2
▼- Proteomic ratio reveals subtype-specific genetic mechanisms and therapeutic targets in osteoarthritis
Clinical proteomics · 2025 · Journal Article
Wang Y, Yang X, Zhang Q, Che H, et al.
📚 1 cit. - Genetic insights into serum cathepsins as diagnostic and therapeutic targets in knee and hip osteoarthritis
Scientific reports · 2024 · Journal Article
Shao Z, Gao H, Han Q, Ning E, et al.
📚 4 cit.🎯 RCR 1.04
Qualité de vie / PROMs2
▼
Qualité de vie / PROMs2
▼- Performance of patient-reported outcomes in the assessment of rheumatoid arthritis disease activity:the experience of the ESPOIR cohort
Clinical and experimental rheumatology · 2016 · Comparative Study
Che H, Combe B, Morel J, Cantagrel A, et al.
📚 8 cit.🩺 Clinique - Impaired quality of life in adults with X-linked hypophosphatemia and skeletal symptoms
European journal of endocrinology · 2016 · Journal Article
Che H, Roux C, Etcheto A, Rothenbuhler A, et al.
📚 125 cit.🎯 RCR 6.45🔬→🩺 Translationnel
Revue / méta-analyse2
▼
Revue / méta-analyse2
▼- Risk of fracture and low bone mineral density in adults with inflammatory bowel diseases. A systematic literature review with meta-analysis
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018 · Journal Article
Szafors P, Che H, Barnetche T, Morel J, et al.
📚 76 cit.🎯 RCR 3.93🔬→🩺 Translationnel - Risk of herpes/herpes zoster during anti-tumor necrosis factor therapy in patients with rheumatoid arthritis. Systematic review and meta-analysis
Joint bone spine · 2014 · Journal Article
Che H, Lukas C, Morel J, Combe B
📚 63 cit.🎯 RCR 2.45🔬→🩺 Translationnel
Lupus1
▼
Lupus1
▼- Glaucoma secondary to systemic lupus erythematosus
Chinese medical journal · 2014 · Journal Article
Zhang J, Huang W, Gao X, Che H, et al.
📚 4 cit.
