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Rhumatologue

Professeur HUBERT MAROTTE

📍 Saint-Priest-en-Jarez (42)HospitalierRPPS 10004043898
📊 Reconnaissance scientifique : 39/100📝 337 articles publiés📚 HAL (8)🎓 5 thèses dirigées

Diplômes

🎓 DES & spécialité ordinale

  • DES Rhumatologie
  • Rhumatologie (SM)

🎓 Diplômes

  • DE Docteur en médecine

Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.

Thèses universitaires

Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.

Direction de thèses

🎓 5 thèses dirigées

Source theses.fr — signal de direction d'équipe / statut PU-PH (à confirmer via le site universitaire).

Activité de recherche & publications

Source : bases de données publiques (OpenAlex, PubMed).

h-index

39

h articles cités ≥ h fois chacun. Un h de 39 = 39 publications avec 39+ citations.

Citations

5 220

Publications

337

i10-index

97

Thématiques principales

  • Rheumatoid Arthritis Research and Therapies ×158
  • Spondyloarthritis Studies and Treatments ×45
  • Biosimilars and Bioanalytical Methods ×32
  • Systemic Lupus Erythematosus Research ×31
  • Autoimmune and Inflammatory Disorders Research ×23

Affiliations FR : Inserm · Institute Cancer De La Loire Lucien Neuwirth · Centre Hospitalier Universitaire de Saint-Étienne

Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.

Bibliographie

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Lieu de consultation

  • HOPITAL NORD - CHU42

    Avenue ALBERT RAIMOND, 42277 Saint-Priest-en-Jarez

    0477828002Hospitalier

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Articles de presse (3)

Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).

Top publications · les plus citées

  • 1
    Navigating adalimumab biosimilars: an expert opinion

    Journal of comparative effectiveness research · 2023

    📚 22 citations🎯 RCR 4.07Top 11% NIH🔓 Open Access
    Lire l'abstract Crossref ↓

    The patent expiry of Humira ® in 2018 opened up the current European market to eight adalimumab biosimilars – (in alphabetical order) Amgevita ® , Amsparity ® , Hulio ® , Hukyndra ® , Hyrimoz ® , Idacio ® , Imraldi ® and Yuflyma ® – for the treatment of various immune and inflammatory conditions. Amjevita, Hadlima ® , Hyrimoz and Yuflyma have recently become available in the USA, with others expected to reach this market in 2023 as the US patent protection for Humira ends. Although adalimumab biosimilars demonstrate efficacy, safety and immunogenicity similar to the originator, they may differ in product excipient(s) and preservatives, along with their device type(s). Physicians may find it both difficult and time consuming to navigate their way among the array of available adalimumab biosimilars when they need to make a treatment decision. This article explores the characteristics of various adalimumab biosimilars to help clinicians navigate the various options available across Europe and the USA. In addition to drug selection, effective patient–physician communication is needed to nurture realistic patient expectations and minimise potential nocebo effects when prescribing biosimilars.

  • 2
    YAP Transcriptional Activity Dictates Cell Response to TNF In Vitro

    Frontiers in immunology · 2022

    📚 19 citations🎯 RCR 1.57🔓 Open Access
    Lire l'abstract Crossref ↓

    YAP/TAZ are transcription co-factors recently described responsive to pro-inflammatory cytokines and involved in inflammatory-related disorders. However, the role of tumor necrosis factor (TNF), a major pro-inflammatory cytokine, on YAP signaling is not well understood and controversial. Here, we observe in vitro, using wild type and YAP knockout HEK293 cells, that TNF triggers YAP nuclear translocation and transcriptional activity, thus being dependent on Rho family of GTPases. In response to TNF, YAP transcriptional activity orientates cell fate toward survival. Transcriptional analysis with Nanostring technology reveals that YAP modulates TNF-induced increase in fibro-inflammatory pathways such as NF-κB, inflammasomes, cytokines or chemokines signaling and pro-fibrotic pathways involving TGF-β and extracellular matrix remodeling. Therefore, in response to TNF, YAP acts as a sustainer of the inflammatory response and as a molecular link between inflammation and fibrotic processes. This work identifies that YAP is critical to drive several biological effects of TNF which are involved in cancer and inflammatory disorders.

  • 3
    Efficacy and safety of combination targeted therapies in immune-mediated inflammatory disease: the COMBIO study

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2023

    📚 18 citations🎯 RCR 2.22Top 24% NIH🔓 Open Access📄 PDF gratuit ↗

Publications scientifiques (50) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Transversal23

Anti-TNF7

csDMARDs6

Essai clinique4

Biothérapies non-anti-TNF2

AINS1

Arthrite juvénile1

Biomarqueurs / Auto-Ac1

Corticothérapie1

Épidémiologie & registres1

IA en rhumatologie1

Pharmacovigilance1

Recommandations1

Revue générale1

Datasets & protocoles partagés

Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).

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