Docteur PASCAL GUGGENBUHL
✨ Profil synthétique
IA · 30/04/2026Le Docteur Pascal Guggenbuhl est un rhumatologue hospitalier à Rennes, membre du GRIO pour l'ostéoporose. Il est auteur de 307 publications et a dirigé plusieurs thèses dans le domaine de la biologie et des sciences de la santé. Ses recherches portent principalement sur la santé osseuse, l'ostéoporose, les infections orthopédiques et les maladies rhumatismales.
Expertises présumées
- Ostéoporose
- Goutte
- Rhumatoides
- Infections orthopédiques
- Santé osseuse
- Traitement par csDMARDs
- Corticothérapie
- Génétique des maladies rhumatismales
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- DES Rhumatologie
- Rhumatologie (SM)
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Thèses universitaires
Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.
Direction de thèses
🎓 3 thèses dirigéesMécanismes impliqués dans le développement de l'ostéoporose au cours des surcharges en fer
2022Doctorant·e : François Robin
Nutrition et pathologies métaboliques🎓 Rennes 1Impact d’une exposition au fer sur l’axe S1P/S1PR dans la lignée ostéoblastique humaine MG-63
2017Doctorant·e : Lucas Peltier
Biologie et sciences de la santé🎓 Rennes 1Caractérisation in vitro et in vivo du rôle des ostéoblastes dans l'ostéoporose associée aux surcharges en fer
2012Doctorant·e : Mathilde Doyard
Biologie et sciences de la santé🎓 Rennes 1
Source theses.fr — signal de direction d'équipe / statut PU-PH (à confirmer via le site universitaire).
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
36
h articles cités ≥ h fois chacun. Un h de 36 = 36 publications avec 36+ citations.
Citations
4 197
Publications
308
i10-index
92
Thématiques principales
- Bone health and osteoporosis research ×52
- Orthopedic Infections and Treatments ×40
- Iron Metabolism and Disorders ×30
- Rheumatoid Arthritis Research and Therapies ×29
- Gout, Hyperuricemia, Uric Acid ×25
Affiliations FR : Inserm · Université Rennes 2 · Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Prognostic Value of Combining Serum Tryptase and Bone Mineral Density in Predicting Fractures in Systemic Mastocytosis
2026ArticleClinical and Experimental Allergy
Letter to the Editor: More on bone microarchitecture and volumetric BMD in men and women with PLS3 gene variants assessed with HR-pQCT
2025ArticleJournal of Bone and Mineral Research
Interactions entre le métabolisme du fer et le remodelage osseux
2025ArticleRevue du Rhumatisme
Ostéoporose de la grossesse et de la lactation en pratique clinique
2025ArticleRevue du Rhumatisme
Septic pubic Symphysitis: newest radiological, microbiological and outcome findings in a rare and difficult-to-treat infection
2025ArticleClinical Microbiology and Infection
Arthropathies microcristallines
2025ArticleRevue du Praticien (La)
Reconnaître l’ostéopathie induite par le méthotrexate : une préoccupation clinique importante
2025ArticleRevue du Rhumatisme
EULAR 2025 classification criteria for haemochromatosis arthropathy
2025ArticleAnnals of the Rheumatic Diseases
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Livres & ouvrages
- 📕
Analyse de textures appliquée au tissu osseux
2006 · 376 p.
- 📕
ETUDE CLINIQUE, BIOLOGIQUE, HISTOLOGIQUE ET IMMUNOGENETIQUE DU SYNDROME DE GOUGEROT-SJOGREN PRIMITIF
A PROPOS DE 48 OBSERVATIONS
1995
Source : Google Books — filtre catégories médicales/santé/sciences.
Localisation des cabinets
Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.
Lieux de consultation
CHRU RENNES SITE HOPITAL SUD
16 Boulevard DE BULGARIE, 35000 Rennes
☎ 0299284321HospitalierSERVICE DE SOINS SNCF
19 Place DE LA GARE, 35000 Rennes
☎ 0299291114Hospitalier
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Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Articles de presse (3)
Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).
- Hémochromatose. Les Bretons particulièrement touchés - Le Télégramme
📰 Le Télégramme · 28/05/2019
<a href="https://news.google.com/rss/articles/CBMitwFBVV95cUxNeTMzTklLaXFLaC0tRXVDaXJDV05CSEdTUEJKcVpjbk5ndWxfdkkzOGF2LUIyNnVLQU01QXFtZGlHRWw0NUkwdEdDbENlajVPV2RFME90ZG80RXJxdEh4ZjBadmVPdzkydlNQOFUzMG5KSUE0c1prcFEwcEI1MHdRNGU1aDQ3QWwyMVBNSWVQQS0ySDItMDcwREs5bnk3OC1ZUzZwU0FiTGpCc3Bma0dSaHgwZjdXdmc?oc
- Conférence : les corticoïdes, anges ou démons ? - Ouest-France
📰 Ouest-France · 02/03/2015
<a href="https://news.google.com/rss/articles/CBMiogFBVV95cUxNV1FLUXNHR2RSVVdxMEhZNF9Sd3MycXc4aFVLb1lPaDcxSU1heHU0MktpdDBjY0ppdWVUVHNOT1BjQmMzZnFubjl2QTRvcWVreHFhR0hoMmJPQUpNMHZjMElzUVd5QVhFNENVeEZFc3JVWUZwWGZtTU9sQ0VjYTdpZkg0U3VuX1RIaGNteFE2cXp5bmZMRW1JNjJwbV9Eb2YzRUE?oc=5" target="_blank">Conféren
- locale Express - AIX-LES-BAINS. La 57ème semaine de rhumatologie à Aix-les-Bains a fermé ses portes - Le Dauphiné Libéré
📰 Le Dauphiné Libéré · 30/03/2012
<a href="https://news.google.com/rss/articles/CBMisgFBVV95cUxNOGItaEVfTlREVVFlRTVBbS10TzNsdC1IM21Wd053YzE5SnE1NGNOb2k3R28tRnBlU1VYaXRCaFFiVzZwcTRmOWRfSy1BZ0dSMXhDZFduQ1VKNTZ6UjZ4VVpiVXhoRkZYeHVmRzZEVXRmbFotRTBxUm1IbVdFYjlvNzdiMzBaVERSU0hIb0pHdkZObGlFRGVFS1dqRmJQYzZVQ19nSzVxcldGMFlYWWpCdDRB?oc=5" tar
Top publications · les plus citées
- 12018 update of French recommendations on the management of postmenopausal osteoporosis
Joint bone spine · 2018
- 2Genetic analysis of adults heterozygous for ALPL mutations
Journal of bone and mineral metabolism · 2018
📚 42 citations🎯 RCR 2.29Top 23% NIH - 32020 French recommendations on the management of septic arthritis in an adult native joint
Joint bone spine · 2020
Publications scientifiques (50) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal31
▼
Transversal31
▼- EULAR 2025 classification criteria for haemochromatosis arthropathy
Annals of the rheumatic diseases · 2026 · Journal Article
Kiely PD, Finzel S, Farisogullari B, Carroll GJ, et al.
📚 1 cit. - Prognostic Value of Combining Serum Tryptase and Bone Mineral Density in Predicting Fractures in Systemic Mastocytosis
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026 · Journal Article
Robin F, Bureau V, Vivier A, Le Mouel E, et al.
- Letter to the Editor: More on bone microarchitecture and volumetric BMD in men and women with PLS3 gene variants assessed with HR-pQCT
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025 · Journal Article
Vanjak A, Cohen-Solal M, Chapurlat R, Guggenbuhl P, et al.
📚 1 cit. - The use of bisphosphonates in osteoid osteoma and osteoblastoma of difficult location: A useful and safe medical alternative
Joint bone spine · 2025 · Letter
Robin F, Guillin R, Lecigne R, Violas P, et al.
- Septic pubic symphysitis: newest radiological, microbiological, and outcome findings in a rare and difficult-to-treat infection
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2025 · Letter
Tabary S, Robin F, Darrieutort-Laffite C, Lautredoux F, et al.
- [Microcrystalline arthropathies]
La Revue du praticien · 2025 · Journal Article
Chotard É, Guggenbuhl P
- Detection of hypophosphatasia in hospitalised adults in rheumatology and internal medicine departments: a multicentre study over 10 years
RMD open · 2024 · Multicenter Study
Larid G, Vix J, Preuss P, Robin F, et al.
📚 6 cit.🎯 RCR 2.37🔬→🩺 Translationnel - 2023 French recommendations for diagnosing and managing prepatellar and olecranon septic bursitis
Joint bone spine · 2024 · Review
Darrieutort-Laffite C, Coiffier G, Aïm F, Banal F, et al.
- Early-Onset Osteoporosis: Molecular Analysis in Large Cohort and Focus on the PLS3 Gene
Calcified tissue international · 2024 · Journal Article
Mancini M, Chapurlat R, Isidor B, Desjonqueres M, et al.
📚 3 cit. - Septic arthritis of the facet joint is also a severe vertebral infection: A multicenter retrospective study of 65 patients
Joint bone spine · 2024 · Journal Article
Cadiou S, Tuil R, Le Goff B, Hoppé E, et al.
- Bone marrow edema of the sacroiliac joint and anatomical variations: Look back the posterior bony excess. Comment on: "Spine abnormalities associated with bone edema on sacroiliac joints MRI in patients with non-inflammatory chronic back pain" by Marnas et al. Joint Bone Spine 2022;89:105436
Joint bone spine · 2023 · Letter
Cadiou S, Robin F, Lecigne R, Guggenbuhl P, et al.
📚 1 cit. - Management and outcome of native joint septic arthritis: a nationwide survey in French rheumatology departments, 2016-2017
Annals of the rheumatic diseases · 2022 · Journal Article
Richebé P, Coiffier G, Guggenbuhl P, Mulleman D, et al.
📚 7 cit. - WNT11, a new gene associated with early onset osteoporosis, is required for osteoblastogenesis
Human molecular genetics · 2022 · Case Reports
Caetano da Silva C, Edouard T, Fradin M, Aubert-Mucca M, et al.
📚 14 cit.🎯 RCR 1.20 - Relevance of using both aerobic and anaerobic enrichment vials for optimizing rapid diagnosis of osteoarticular infections
Microbial pathogenesis · 2022 · Journal Article
Coiffier G, Ducasse E, Keraudren A, Prat E, et al.
📚 1 cit. - Oxidative and glycolytic skeletal muscles deploy protective mechanisms to avoid atrophy under pathophysiological iron overload
Journal of cachexia, sarcopenia and muscle · 2022 · Journal Article
Martin D, Nay K, Robin F, Rebillard A, et al.
📚 14 cit.🎯 RCR 1.53 - Sacroiliac joint in sarcoidosis on computed tomography: a monocentric retrospective study (SISTER)
Rheumatology international · 2022 · Journal Article
Cadiou S, Coiffier G, Jouneau S, Jego P, et al.
- SARS-CoV-2, polymyalgia rheumatica and giant cell arteritis: COVID-19 vaccine shot as a trigger? Comment on: "Can SARS-CoV-2 trigger relapse of polymyalgia rheumatica?" by Manzo et al. Joint Bone Spine 2021;88:105150
Joint bone spine · 2022 · Letter
Cadiou S, Perdriger A, Ardois S, Albert JD, et al.
📚 24 cit.🎯 RCR 2.60 - Bone mineral density and trabecular bone score assessment in systemic sclerosis: A cross-sectional study
Joint bone spine · 2021 · Letter
Lescoat A, Leroy M, Coiffier G, Cazalets C, et al.
📚 3 cit. - Features and Outcomes of Microcrystalline Arthritis Treated by Biologics: A Retrospective Study
Rheumatology and therapy · 2021 · Journal Article
Doaré E, Robin F, Racapé H, Le Mélédo G, et al.
📚 5 cit. - Surgical management of MILD hyperparathyroidism
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021 · Journal Article
Lecourt A, Creff G, Coudert P, De Crouy Chanel O, et al.
📚 1 cit. - Etiology of avascular osteonecrosis of the femoral head
Morphologie : bulletin de l'Association des anatomistes · 2021 · Journal Article
Guggenbuhl P, Robin F, Cadiou S, Albert JD
📚 24 cit.🎯 RCR 2.89 - Elaboration of a new synovial predictive score of septic origin for acute arthritis on the native joint (RESAS)
Rheumatology (Oxford, England) · 2021 · Journal Article
Coiffier G, Berthoud O, Albert JD, Robin F, et al.
📚 3 cit. - Is ultrasound-guided caudal steroid injection effective in the management of lower lumbar radicular pain? A two-center prospective observational study on 150 patients
Joint bone spine · 2020 · Letter
Robin F, Coiffier G, Albert JD, Darrieutort-Laffite C, et al.
📚 1 cit.🩺 Clinique - 2020 French recommendations on the management of septic arthritis in an adult native joint
Joint bone spine · 2020 · Journal Article
Couderc M, Bart G, Coiffier G, Godot S, et al.
📚 41 cit.🎯 RCR 3.33🔬→🩺 Translationnel - Performance of a new rapid diagnostic test the lactate/glucose ratio of synovial fluid for the diagnosis of septic arthritis
Joint bone spine · 2020 · Journal Article
Berthoud O, Coiffier G, Albert JD, Gougeon-Jolivet A, et al.
📚 15 cit.🎯 RCR 1.01 - Vitamin D Supplementation in France in patients with or at risk for osteoporosis: Recent data and new practices
Joint bone spine · 2020 · Journal Article
Souberbielle JC, Cormier C, Cavalier E, Breuil V, et al.
📚 11 cit.🔬→🩺 Translationnel - Spleen iron, molybdenum, and manganese concentrations are coregulated in hepcidin-deficient and secondary iron overload models in mice
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019 · Journal Article
Cavey T, Latour C, Island ML, Leroyer P, et al.
📚 11 cit.🔬→🩺 Translationnel - Broad-range 16 s rDNA PCR in synovial fluid does not improve the diagnostic performance of septic arthritis in native joints in adults: cross-sectional single-center study in 95 patients
Clinical rheumatology · 2019 · Journal Article
Coiffier G, David C, Gauthier P, Le Bars H, et al.
📚 17 cit.🎯 RCR 1.41🔬→🩺 Translationnel - High bone mass in adults
Joint bone spine · 2018 · Journal Article
Paccou J, Michou L, Kolta S, Debiais F, et al.
📚 17 cit.🔬→🩺 Translationnel - Iron as a Therapeutic Target in HFE-Related Hemochromatosis: Usual and Novel Aspects
Pharmaceuticals (Basel, Switzerland) · 2018 · Journal Article
Loréal O, Cavey T, Robin F, Kenawi M, et al.
📚 8 cit. - 2018 update of French recommendations on the management of postmenopausal osteoporosis
Joint bone spine · 2018 · Journal Article
Briot K, Roux C, Thomas T, Blain H, et al.
📚 88 cit.🎯 RCR 4.81🔬→🩺 Translationnel
Goutte6
▼
Goutte6
▼- From skin to microscope, case report of a rare manifestation of tophaceous gout: Miliary gout
International journal of rheumatic diseases · 2024 · Case Reports
Théau C, Pauline B, Emilie C, Pascal G, et al.
📚 4 cit.🎯 RCR 1.81 - External validation of Gout-calculator performance on a cohort of acute arthritis (SYNOLACTATE) sparing distal joints such as hallux and midfoot. A cross-sectional study of 170 patients
Clinical rheumatology · 2021 · Journal Article
Robin F, Berthoud O, Albert JD, Cadiou S, et al.
📚 1 cit. - Non-pharmacologic measures for gout management in the prospective GOSPEL cohort: Physicians' practice and patients' compliance profiles
Joint bone spine · 2019 · Journal Article
Chapron A, Chopin T, Esvan M, Ea HK, et al.
📚 4 cit.🩺 Clinique - Difficult-to-treat gout flares: eligibility for interleukin-1 inhibition in private practice is uncommon according to current EMA approval
Rheumatology (Oxford, England) · 2019 · Journal Article
Pascart T, Norberciak L, Ea HK, Graf S, et al.
📚 19 cit.🎯 RCR 1.07🔬→🩺 Translationnel - Patients With Early-Onset Gout and Development of Earlier Severe Joint Involvement and Metabolic Comorbid Conditions: Results From a Cross-Sectional Epidemiologic Survey
Arthritis care & research · 2019 · Comparative Study
Pascart T, Norberciak L, Ea HK, Guggenbuhl P, et al.
📚 24 cit.🎯 RCR 1.31🔬→🩺 Translationnel - Reply to the comment of Mourgues et al., 2012. American guidelines for the management of gout as seen by general practitioners
Joint bone spine · 2019 · Letter
Goossens J, Lancrenon S, Lanz S, Ea HK, et al.
csDMARDs3
▼
csDMARDs3
▼- METHOFRACT, a methotrexate osteopathy multicentre cohort study
RMD open · 2025 · Journal Article
Robin F, Ghossan R, Mehsen-Cetre N, Triquet L, et al.
📚 2 cit. - Methotrexate osteopathy: Old description, but still important to know
ACR open rheumatology · 2025 · Letter
Robin F, Leloix A, Guggenbuhl P, Gandemer V, et al.
📚 2 cit. - Methotrexate osteopathy: five cases and systematic literature review
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021 · Journal Article
Robin F, Cadiou S, Albert JD, Bart G, et al.
📚 32 cit.🎯 RCR 2.78
Génétique2
▼
Génétique2
▼- Differences in bone microarchitecture between genetic and secondary iron-overload mouse models suggest a role for hepcidin deficiency in iron-related osteoporosis
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023 · Journal Article
Robin F, Chappard D, Leroyer P, Latour C, et al.
📚 6 cit. - Genetic analysis of adults heterozygous for ALPL mutations
Journal of bone and mineral metabolism · 2018 · Journal Article
Taillandier A, Domingues C, Dufour A, Debiais F, et al.
📚 42 cit.🎯 RCR 2.29🔬→🩺 Translationnel
Revue générale2
▼
Revue générale2
▼- Spondyloarthritis and sarcoidosis: Related or fake friends? A systematic literature review
Joint bone spine · 2020 · Journal Article
Cadiou S, Robin F, Guillin R, Perdriger A, et al.
📚 9 cit.🔬→🩺 Translationnel - Back pain following instillations of BCG for superficial bladder cancer is not a reactive complication: review of 30 Mycobacterium bovis BCG vertebral osteomyelitis cases
Clinical rheumatology · 2019 · Case Reports
Cadiou S, Al Tabaa O, Nguyen CD, Faccin M, et al.
📚 11 cit.
Case report / série1
▼
Case report / série1
▼- A case report of a rare form of calcium pyrophosphate disease: sacroiliitis with soft tissue involvement mimicking an infectious disease
Rheumatology advances in practice · 2024 · Case Reports
Leloix A, Hervouet M, Chotard É, Guillin R, et al.
Corticothérapie1
▼
Corticothérapie1
▼- [Is it (really) necessary to treat all postmenopausal women receiving corticosteroid therapy with bone preventive therapy?]
La Revue de medecine interne · 2021 · Journal Article
Robin F, Lescoat A, Jego P, Guggenbuhl P
CPPD1
▼
CPPD1
▼- Calcium pyrophosphate deposition (CPPD) in a liver transplant patient: are hypomagnesemia, tacrolimus or both guilty? A case-based literature review
Rheumatology international · 2022 · Case Reports
Cadiou S, Le Gruyer A, Giguet B, Robin F, et al.
Épidémiologie & registres1
▼
Épidémiologie & registres1
▼- The French multicentre elevated bone mass study: prevalence and causes
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021 · Journal Article
Paccou J, Javier RM, Henry-Desailly I, Ternynck C, et al.
📚 5 cit.🔬→🩺 Translationnel
Ostéomalacie1
▼
Ostéomalacie1
▼- Real-world efficacy and safety of burosumab in tumor-induced osteomalacia: case series from an early access program
JBMR plus · 2025 · Case Reports
Cadiou S, Chapurlat R, Couture G, Guggenbuhl P, et al.
📚 4 cit.
Ostéoporose1
▼
Ostéoporose1
▼- Denosumab in the management of Aneurysmal bone cyst
Joint bone spine · 2022 · Journal Article
Maximen J, Robin F, Tronchot A, Rossetti A, et al.
📚 36 cit.🎯 RCR 5.11
Datasets & protocoles partagés
Features and Outcomes Of Microcrystalline Arthritis Treated by Biologics: A Retrospective Study
Audiovisual2021Adis Journals<strong>Article full text</strong> <br> The above summary slide represents the opinions of the authors. For a full list of declarations, including funding and author disclosure statements, please see the full text online
Features and Outcomes Of Microcrystalline Arthritis Treated by Biologics: A Retrospective Study
Audiovisual2021Adis Journals<strong>Article full text</strong> <br> The above summary slide represents the opinions of the authors. For a full list of declarations, including funding and author disclosure statements, please see the full text online
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).