Rhumatologue

Docteur YANNICK DEGBOE

📍 Toulouse (31)HospitalierRPPS 10100530525

📊 Reconnaissance scientifique : 23/100📝 156 articles publiés📚 HAL (8)

✨ Profil synthétique

IA · 30/04/2026

Le Docteur YANNICK DEGBOE est un rhumatologue hospitalier à Toulouse, avec une expertise dans la recherche sur les maladies rhumatismales. Ses travaux de recherche portent principalement sur la polyarthrite rhumatoïde, la spondylarthrite et l'ostéoporose. Il a dirigé des recherches dans le domaine de l'immunologie et a publié 156 articles scientifiques, avec un h-index de 23.

Expertises présumées

Polyarthrite rhumatoïde
Spondylarthrite
Ostéoporose
Thérapies anti-TNF
Biothérapies non anti-TNF
Essais cliniques en rhumatologie
Épidémiologie des maladies rhumatismales

Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.

Diplômes

🎓 DES & spécialité ordinale

DES Rhumatologie
Rhumatologie (SM)

🎓 Diplômes

DE Docteur en médecine

Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.

Thèses universitaires

Modulation thérapeutique du phénotype du macrophage dans la polyarthrite rhumatoïde
2018
Therapeutic modulation of the phenotype of the macrophage in rheumatoid arthritis
Immunologie🎓 Toulouse 3
Direction : Jean-Luc Davignon

Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.

Activité de recherche & publications

Source : bases de données publiques (OpenAlex, PubMed).

h-index

h articles cités ≥ h fois chacun. Un h de 23 = 23 publications avec 23+ citations.

Citations

1 643

Publications

156

i10-index

Thématiques principales

Rheumatoid Arthritis Research and Therapies ×53
Spondyloarthritis Studies and Treatments ×27
Bone health and osteoporosis research ×20
Mast cells and histamine ×19
Bone Metabolism and Diseases ×18

Affiliations FR : Centre National de la Recherche Scientifique · Université Toulouse III - Paul Sabatier · Inserm

Voir sur OpenAlex ↗🆔 ORCID 0000-0002-4293-8596

Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.

Bibliographie

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Lieu de consultation

HOPITAL PURPAN CHU TOULOUSE
BAT PIERRE PAUL RIQUET — Place DU DR BAYLAC, 31059 Toulouse
☎ 0561772233Hospitalier🏥 Centre CHU ↗

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

📊 Comprendre le remboursement

Prendre rendez-vous & contact

🗓 Trouver sur Doctolib 📇 Ajouter à mes contacts

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Articles de presse (1)

Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).

Découvrez le classement des meilleurs médecins spécialistes d'Occitanie - L'Opinion Indépendante
📰 L'Opinion Indépendante · 27/05/2023
<a href="https://news.google.com/rss/articles/CBMimgFBVV95cUxNYlR5UjBneERIak80N0xBS3ZEV3RhUlkwNkxxUFJVRUtOa2pYOHFIaFU3aG4wS0hCWjE1N3RJdHZ6Y0k3OXZ0TXVfNEU0QXFlZ3h0endiR1oxOC01NElndEM3aGhOcFZtTUN1Rkk3Zk5CQkpRNzZLaU9mbENaZlhoZE1WMHY5bUltSnMwT2xRZ2twQ3NPZ3pTdFdn0gGfAUFVX3lxTFB3VktLVFFlRF9OSjFkUHVvRHJOTm

Top publications · les plus citées

1
Polarization of Rheumatoid Macrophages by TNF Targeting Through an IL-10/STAT3 Mechanism
Frontiers in immunology · 2019
📚 147 citations🎯 RCR 6.51Top 5% NIH🔓 Open Access📄 PDF gratuit ↗
2
Risk of losing remission, low disease activity or radiographic progression in case of bDMARD discontinuation or tapering in rheumatoid arthritis: systematic analysis of the literature and meta-analysis
Annals of the rheumatic diseases · 2018
📚 49 citations🎯 RCR 2.37Top 22% NIH
3
VEXAS syndrome in a patient with previous spondyloarthritis with a favourable response to intravenous immunoglobulin and anti-IL17 therapy
Rheumatology (Oxford, England) · 2021
📚 47 citations🎯 RCR 2.99Top 16% NIH

Publications scientifiques (50) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Transversal27

▼

Predicting Clinical Response to Monoclonal TNF Inhibitors in Rheumatoid Arthritis: A Transcriptomic Approach Based on Transmembrane TNF Reverse Signaling and Nrf2 Activation
Diagnostics (Basel, Switzerland) · 2025 · Journal Article
Diallo K, Degboé Y, Baron M, Bellin-Robert A, et al.
📚 3 cit.
Management of Bone Health in Adult Mastocytosis
Current osteoporosis reports · 2025 · Journal Article
Degboé Y, Nezzar C, Alary P, Maëva M, et al.
📚 4 cit.
Evidence for Pro-Inflammatory Activity of LTα3 on Macrophages: Significance for Experimental Arthritis and for Therapeutic Switching in Rheumatoid Arthritis Patients
International journal of molecular sciences · 2025 · Journal Article
Benezech A, Gottenberg JE, Degboé Y, Kruglov A, et al.
Rheumatic adverse effects with biologics targeting type 2 inflammation in severe asthma: A VigiBase study
The journal of allergy and clinical immunology. In practice · 2025 · Journal Article
Laux M, Montastruc F, Degboe Y, Guilleminault L
📚 3 cit.
The serum levels of FGF23, sclerostin, osteoprotegerin do not explain the inverse relationship between coronary calcifications and bone mineral density evaluated using computed tomography
Frontiers in cardiovascular medicine · 2025 · Journal Article
Ferrières L, Laroche M, Degboé Y, Jaafar A, et al.
📚 1 cit.
Lumbar muscle involvement in the occurrence of osteoporotic vertebral fracture
Research in diagnostic and interventional imaging · 2024 · Journal Article
Lambeaux C, Lapègue F, Fayolle H, Degboe Y, et al.
📚 1 cit.
Editorial: Immune-checkpoint inhibitors in anti-cancer armamentarium: a double-edged sword in risk of developing autoimmunity and immune-related adverse effects
Frontiers in oncology · 2024 · Editorial
Tulunay Virlan A, Cafaro G, Sunzini F, Degboe Y, et al.
Ten-year radiographic and functional outcomes in rheumatoid arthritis patients in remission compared to patients in low disease activity
Arthritis research & therapy · 2023 · Journal Article
Ruyssen-Witrand A, Guernec G, Dupont J, Lapuyade D, et al.
📚 5 cit.🎯 RCR 1.11🔬→🩺 Translationnel
Characteristics of the (Auto)Reactive T Cells in Rheumatoid Arthritis According to the Immune Epitope Database
International journal of molecular sciences · 2023 · Journal Article
Carlé C, Degboe Y, Ruyssen-Witrand A, Arleevskaya MI, et al.
📚 11 cit.🎯 RCR 1.49
Loss of bone mineral density in hemiplegic patients after stroke: Prospective single-center study
Revue neurologique · 2022 · Journal Article
Potin P, Degboé Y, Couture G, Marque P, et al.
📚 6 cit.
How does age determine the development of human immune-mediated arthritis?
Nature reviews. Rheumatology · 2022 · Journal Article
Degboe Y, Vastert SJ, Prakken BJ, McInnes IB
📚 16 cit.🎯 RCR 1.51
Factors associated with drug-free remission at 5-year in early onset axial spondyloarthritis patients: Data from the DESIR cohort
Joint bone spine · 2022 · Journal Article
Ruyssen-Witrand A, Rousseau V, Sommet A, Goupille P, et al.
📚 4 cit.🩺 Clinique
Repolarization of Unbalanced Macrophages: Unmet Medical Need in Chronic Inflammation and Cancer
International journal of molecular sciences · 2022 · Journal Article
Degboé Y, Poupot R, Poupot M
📚 29 cit.🎯 RCR 2.35
Hypophosphatasia: A Case of Two Patients With Spinal Cord Compression From Increase in Ligamentous Ossifications During Treatment
JBMR plus · 2021 · Journal Article
Laroche M, Couture G, Faruch M, Ruyssen-Witrand A, et al.
Apremilast inhibits inflammatory osteoclastogenesis
Rheumatology (Oxford, England) · 2021 · Journal Article
Degboé Y, Sunzini F, Sood S, Bozec A, et al.
📚 6 cit.
VEXAS syndrome in a patient with previous spondyloarthritis with a favourable response to intravenous immunoglobulin and anti-IL17 therapy
Rheumatology (Oxford, England) · 2021 · Case Reports
Magnol M, Couvaras L, Degboé Y, Delabesse E, et al.
📚 47 cit.🎯 RCR 2.99🔬→🩺 Translationnel
Evidence for tmTNF reverse signaling in vivo: Implications for an arginase-1-mediated therapeutic effect of TNF inhibitors during inflammation
iScience · 2021 · Journal Article
Diallo K, Simons N, Sayegh S, Baron M, et al.
📚 10 cit.
Comment on: Diagnosis of fibromyalgia: comparison of the 2011/2016 ACR and AAPT criteria and validation of the modified Fibromyalgia Assessment Status
Rheumatology (Oxford, England) · 2020 · Journal Article
Couture G, Degboe Y, Geniez C, Tack I, et al.
Inhibition of Osteoclastogenesis by the RNA-Binding Protein QKI5: a Novel Approach to Protect from Bone Resorption
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020 · Journal Article
Rauwel B, Degboé Y, Diallo K, Sayegh S, et al.
📚 13 cit.
Reduced progression of bone erosion in cytomegalovirus seropositive rheumatoid arthritis patients
Arthritis research & therapy · 2020 · Journal Article
Rauwel B, Degboé Y, Nigon D, Boyer JF, et al.
📚 5 cit.
Mast cell activation syndrome: High frequency of skin manifestations and anaphylactic shock
Allergology international : official journal of the Japanese Society of Allergology · 2019 · Case Reports
Casassa EA, Mailhol C, Tournier E, Laurent C, et al.
📚 3 cit.
Complex regional pain syndrome secondary to everolimus: Two cases
Joint bone spine · 2019 · Case Reports
Magnol M, Degboé Y, Couture G, Constantin A, et al.
📚 3 cit.
Association between IL23R and ERAP1 polymorphisms and sacroiliac or spinal MRI inflammation in spondyloarthritis: DESIR cohort data
Arthritis research & therapy · 2019 · Clinical Trial
Ruyssen-Witrand A, Luxembourger C, Cantagrel A, Nigon D, et al.
📚 14 cit.🩺 Clinique
Corrigendum: Rheumatoid Synovial Fluids Regulate the Immunomodulatory Potential of Adipose-Derived Mesenchymal Stem Cells Through a TNF/NF-κB-Dependent Mechanism
Frontiers in immunology · 2019 · Published Erratum
Sayegh S, El Atat O, Diallo K, Rauwel B, et al.
📚 2 cit.
Rheumatoid Synovial Fluids Regulate the Immunomodulatory Potential of Adipose-Derived Mesenchymal Stem Cells Through a TNF/NF-κB-Dependent Mechanism
Frontiers in immunology · 2019 · Journal Article
Sayegh S, El Atat O, Diallo K, Rauwel B, et al.
📚 43 cit.🎯 RCR 2.33
Polarization of Rheumatoid Macrophages by TNF Targeting Through an IL-10/STAT3 Mechanism
Frontiers in immunology · 2019 · Journal Article
Degboé Y, Rauwel B, Baron M, Boyer JF, et al.
📚 147 cit.🎯 RCR 6.51🔬→🩺 Translationnel
DKK1 and sclerostin are early markers of relapse in multiple myeloma
Bone · 2018 · Journal Article
Mabille C, Ruyssen-Witrand A, Degboe Y, Gennero I, et al.
📚 16 cit.🩺 Clinique

Épidémiologie & registres4

▼

The Prevalence Of Osteoporosis Is Low in Adult Cutaneous Mastocytosis Patients
The journal of allergy and clinical immunology. In practice · 2024 · Journal Article
Degboé Y, Severino-Freire M, Couture G, Apoil PA, et al.
📚 5 cit.🎯 RCR 1.41
Diagnosis and treatment of Tropheryma whipplei infection in patients with inflammatory rheumatic disease: Data from the French Tw-IRD registry
The Journal of infection · 2024 · Journal Article
Caillet Portillo D, Puéchal X, Masson M, Kostine M, et al.
📚 10 cit.🎯 RCR 3.31
Frequency of isolated cutaneous involvement in adult mastocytosis: a cohort study
Journal of the European Academy of Dermatology and Venereology : JEADV · 2019 · Journal Article
Fradet M, Negretto M, Tournier E, Laurent C, et al.
📚 6 cit.
Higher prevalence of vertebral fractures in systemic mastocytosis, but not in cutaneous mastocytosis and idiopathic mast cell activation syndrome
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019 · Journal Article
Degboé Y, Eischen M, Apoil PA, Mailhol C, et al.
📚 13 cit.

Ostéoporose4

▼

Strategies for denosumab discontinuation in postmenopausal osteoporosis
Joint bone spine · 2026 · Journal Article
Degboé Y, Couture G
📚 1 cit.
Discontinuation of Denosumab: Gradual Decrease in Doses Preserves Half of the Bone Mineral Density Gain at the Lumbar Spine
JBMR plus · 2023 · Journal Article
Laroche M, Couture G, Degboé Y
📚 12 cit.🎯 RCR 1.84
Juvenile osteoporosis with calvarial doughnuts: Progressive high-turnover bone loss responsive to bisphosphonate therapy
Joint bone spine · 2020 · Letter
Couture G, Degboe Y, Baujat G, Cormier-Daire V, et al.
📚 2 cit.
Effect of risedronate on bone loss at discontinuation of denosumab
Bone reports · 2020 · Journal Article
Laroche M, Couture G, Ruyssen-Witrand A, Constantin A, et al.
📚 22 cit.🎯 RCR 1.62🔬→🩺 Translationnel

Revue / méta-analyse3

▼

Impact of tapering targeted therapies (bDMARDs or JAKis) on the risk of serious infections and adverse events of special interest in patients with rheumatoid arthritis or spondyloarthritis: a systematic analysis of the literature and meta-analysis
Arthritis research & therapy · 2020 · Journal Article
Vinson D, Molet-Benhamou L, Degboé Y, den Broeder A, et al.
📚 20 cit.🎯 RCR 1.09🔬→🩺 Translationnel
Short-term risk of major adverse cardiovascular events or congestive heart failure in patients with psoriatic arthritis or psoriasis initiating a biological therapy: a meta-analysis of randomised controlled trials
RMD open · 2019 · Journal Article
Champs B, Degboé Y, Barnetche T, Cantagrel A, et al.
📚 33 cit.🎯 RCR 1.76🔬→🩺 Translationnel
Risk of losing remission, low disease activity or radiographic progression in case of bDMARD discontinuation or tapering in rheumatoid arthritis: systematic analysis of the literature and meta-analysis
Annals of the rheumatic diseases · 2018 · Journal Article
Henaux S, Ruyssen-Witrand A, Cantagrel A, Barnetche T, et al.
📚 49 cit.🎯 RCR 2.37🔬→🩺 Translationnel

Anti-TNF2

▼

Asthma Reporting with Anti-TNFα Drugs used in Inflammatory Joint Diseases: A Vigibase® Study with Disproportionality Analysis
Lung · 2026 · Journal Article
Nocenti M, Montastruc F, Degboe Y, Guilleminault L
Background Glucocorticoid Therapy Has No Impact on Efficacy and Safety of Abatacept or Adalimumab in Patients with Rheumatoid Arthritis
Journal of clinical medicine · 2020 · Journal Article
Degboé Y, Schiff M, Weinblatt M, Fleischmann R, et al.
📚 2 cit.🔬→🩺 Translationnel

Biothérapies non-anti-TNF2

▼

Background Glucocorticoid Therapy Has No Impact on Efficacy and Safety of Abatacept or Adalimumab in Patients with Rheumatoid Arthritis
Journal of clinical medicine · 2020 · Journal Article
Degboé Y, Schiff M, Weinblatt M, Fleischmann R, et al.
📚 2 cit.🔬→🩺 Translationnel
A single nucleotide polymorphism of IL6-receptor is associated with response to tocilizumab in rheumatoid arthritis patients
The pharmacogenomics journal · 2019 · Journal Article
Luxembourger C, Ruyssen-Witrand A, Ladhari C, Rittore C, et al.
📚 23 cit.🎯 RCR 1.20🔬→🩺 Translationnel

Essai clinique2

▼

Comparison of two strategies of glucocorticoid withdrawal in patients with rheumatoid arthritis in low disease activity (STAR): a randomised, placebo- controlled, double-blind trial
Annals of the rheumatic diseases · 2025 · Journal Article
Ruyssen-Witrand A, Brusq C, Masson M, Bongard V, et al.
📚 8 cit.🎯 RCR 3.62🩺 Clinique
Short-term risk of major adverse cardiovascular events or congestive heart failure in patients with psoriatic arthritis or psoriasis initiating a biological therapy: a meta-analysis of randomised controlled trials
RMD open · 2019 · Journal Article
Champs B, Degboé Y, Barnetche T, Cantagrel A, et al.
📚 33 cit.🎯 RCR 1.76🔬→🩺 Translationnel

Risque cardio-vasculaire2

▼

Increased Cardiovascular Risk in Psoriatic Arthritis: Results From a Case-Control Monocentric Study
Frontiers in medicine · 2022 · Journal Article
Degboé Y, Koch R, Zabraniecki L, Jamard B, et al.
📚 8 cit.🎯 RCR 1.09
No impact of anti-Rank ligand and PTH analogs on cardiovascular risk in postmenopausal osteoporosis: a systematic literature review and meta-analysis
Archives of osteoporosis · 2020 · Journal Article
Ferrieres L, Degboe Y, Laroche M, Constantin A, et al.
📚 13 cit.🔬→🩺 Translationnel

Biomarqueurs / Auto-Ac1

▼

Pre-rheumatoid arthritis and ACPA: Contribution of ACPAs in the pathogeny of pre-disease stage
Joint bone spine · 2021 · Editorial
Degboé Y
📚 1 cit.

Corticothérapie1

▼

Comparison of two strategies of glucocorticoid withdrawal in patients with rheumatoid arthritis in low disease activity (STAR): a randomised, placebo- controlled, double-blind trial
Annals of the rheumatic diseases · 2025 · Journal Article
Ruyssen-Witrand A, Brusq C, Masson M, Bongard V, et al.
📚 8 cit.🎯 RCR 3.62🩺 Clinique

csDMARDs1

▼

Psychiatric Disorders and Hydroxychloroquine for Coronavirus Disease 2019 (COVID-19): A VigiBase Study
Drug safety · 2020 · Journal Article
Garcia P, Revet A, Yrondi A, Rousseau V, et al.
📚 28 cit.🎯 RCR 1.74

Lombalgie1

▼

Prevalence of inflammatory posterior arch abnormalities on lumbar spine MRI in spondyloarthritis patients compared with low back pain patients
European radiology · 2019 · Comparative Study
Braun H, Geniez C, Degboe Y, Constantin A, et al.
📚 7 cit.

Revue générale1

▼

Modulation of T-cell responses by anti-tumor necrosis factor treatments in rheumatoid arthritis: a review
Arthritis research & therapy · 2018 · Journal Article
Davignon JL, Rauwel B, Degboé Y, Constantin A, et al.
📚 47 cit.🎯 RCR 1.85🔬→🩺 Translationnel

Sjögren1

▼

Sjögren's syndrome associated with erosive rheumatoid arthritis alters its prognosis and long-term therapeutic response: a case-control study
Rheumatology international · 2023 · Journal Article
Laroche M, Degboe Y, Constantin A
📚 7 cit.🎯 RCR 1.24

Spondyloarthrite1

▼

Biological DMARD efficacy in psoriatic arthritis: a systematic literature review and meta-analysis on articular, enthesitis, dactylitis, skin and functional outcomes
Clinical and experimental rheumatology · 2020 · Journal Article
Simons N, Degboé Y, Barnetche T, Cantagrel A, et al.
📚 18 cit.🎯 RCR 1.15🔬→🩺 Translationnel

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