Docteur Frédéric LIOTE
✨ Profil synthétique
IA · 04/05/2026Le Docteur Frédéric LIOTE est un rhumatologue hospitalier à Paris, avec une activité de recherche importante dans le domaine de la rhumatologie. Ses travaux de recherche portent principalement sur la goutte, l'hyperuricémie, l'arthrite rhumatoïde, la spondylarthrite et le lupus érythémateux systémique. Il a dirigé plusieurs thèses dans le domaine de la biologie de l'os et des articulations.
Expertises présumées
- Goutte
- Hyperuricémie
- Arthrite rhumatoïde
- Spondylarthrite
- Lupus érythémateux systémique
- Biologie de l'os et des articulations
- Thérapies ciblées non-anti-TNF
- Pathologie des tissus calcifiés
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- Rhumatologie (SM)
📚 CES (Certificat d'Études Spéciales)
- CES Rhumatologie
🎯 Capacités
- Cancérologie (C)
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Direction de thèses
🎓 4 thèses dirigéesEtude des effets des Bone Morphogenic Proteins sur la phase de consolidation osseuse dans un modèle d'ostéogénèse en distraction
2010Doctorant·e : Frédéric Sailhan
Biologie de l'os, des articulations et biomatériaux des tissus calcifiés🎓 Paris 7Rôle de l'adrénomédulline et du fragment (22-52) adrénomédulline dans la pathogénie de la polyarthrite rhumatoïde
2010Doctorant·e : Marie-Dominique Ah Kioon
Biologie de l'os, des articulations et biomatériaux des tissus calcifiés🎓 Paris 7Effets des cristaux de phosphate de calcium basique sur l'activation et l'apoptose des chondrocytes articulaires : études in vitro
2008Doctorant·e : Hang Korng Ea
Biologie de l'os, des articulations et biomatériaux des tissus calcifiés🎓 Paris 7Effet anti-apoptotique de l'adrénomédulline via son système CRLR/RAMP : implications dans la pathogénie des affections ostéo-articulaires
2007Doctorant·e : Benjamin Uzan
Biologie ostéo-articulaire🎓 Paris 7
Source theses.fr — signal de direction d'équipe / statut PU-PH (à confirmer via le site universitaire).
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
66
h articles cités ≥ h fois chacun. Un h de 66 = 66 publications avec 66+ citations.
Citations
18 035
Publications
577
i10-index
204
Thématiques principales
- Gout, Hyperuricemia, Uric Acid ×175
- Rheumatoid Arthritis Research and Therapies ×90
- Spondyloarthritis Studies and Treatments ×59
- Systemic Lupus Erythematosus Research ×46
- Inflammasome and immune disorders ×42
Affiliations FR : Inserm · Université Paris Cité · Assistance Publique – Hôpitaux de Paris
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Effect of a 1-month methotrexate delay on pneumococcal vaccine immunogenicity and disease control in patients with early rheumatoid arthritis (VACIMRA): an open-label randomised trial
2025ArticleThe Lancet Rheumatology
Time-course of tophus resolution on Dual-energy CT and ultrasound after 24 months of a treat-to-target strategy: Results from GOUT-DECTUS study
2025ArticleJoint Bone Spine
Comment on: Hydroxychloroquine levels in pregnancy and materno–fetal outcomes in Systemic Lupus Erythematosus patients: Reply
2025ArticleRheumatology
Towards the Lowest Efficacious Dose: Results From a Multicenter Noninferiority Randomized Open‐Label Controlled Trial Assessing Tocilizumab or Abatacept Injection Spacing in Rheumatoid Arthritis in Remission
2024ArticleArthritis & rheumatology
Activation of osmo-sensitive LRRC8 anion channels in macrophages is important for micro-crystallin joint inflammation
2024ArticleNature Communications
Towards the lowest efficacious dose (ToLEDo): results of a multicenter non‐inferiority randomized open‐label controlled trial assessing Tocilizumab or Abatacept injection spacing in rheumatoid arthritis in remission
2024ArticleArthritis & rheumatology
Effectiveness of topical sodium thiosulfate for ectopic calcifications and ossifications. Results of the CATSS-O study
2023ArticleSeminars in Arthritis and Rheumatism
Ten-year radiographic and functional outcomes in rheumatoid arthritis patients in remission compared to patients in low disease activity
2023ArticleArthritis Research & Therapy
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Localisation des cabinets
Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.
Lieux de consultation
CDS REAUMUR
106 Rue DE REAUMUR, 75002 Paris 2e Arrondissement
☎ 0155805620Hospitalier© OpenStreetMapCDS CENTRE MEDICALE ODON VALLET
15 Boulevard DU GAL D'ARMEE JEAN SIMON, 75013 Paris 13e Arrondissement
☎ 0186043783Hospitalier© OpenStreetMapGH PARIS SITE SAINT JOSEPH
185 Rue RAYMOND LOSSERAND, 75674 Paris 14e Arrondissement
☎ 0144123500HospitalierCDS MEDICAL ARTHUR VERNES
36 Rue D ASSAS, 75006 Paris 6e Arrondissement
☎ 0144395300Hospitalier
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Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 12018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout
Annals of the rheumatic diseases · 2020
- 2Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages
Annals of the rheumatic diseases · 2020
📚 131 citations🎯 RCR 6.22Top 6% NIH🔓 Open Access - 3Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout
Annals of the rheumatic diseases · 2019
📚 82 citations🎯 RCR 5.11Top 8% NIH🔓 Open Access
Publications scientifiques (50) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal21
▼
Transversal21
▼- Calcium pyrophosphate deposition disease
The Lancet. Rheumatology · 2024 · Journal Article
Pascart T, Filippou G, Lioté F, Sirotti S, et al.
📚 44 cit.🎯 RCR 13.37🔬→🩺 Translationnel - Activation of osmo-sensitive LRRC8 anion channels in macrophages is important for micro-crystallin joint inflammation
Nature communications · 2024 · Journal Article
Chirayath TW, Ollivier M, Kayatekin M, Rubera I, et al.
📚 20 cit.🎯 RCR 3.80 - Features Associated With Different Inflammatory Phenotypes of Calcium Pyrophosphate Deposition Disease: A Study Using Data From the International American College of Rheumatology/EULAR Calcium Pyrophosphate Deposition Classification Criteria Cohort
Arthritis & rheumatology (Hoboken, N.J.) · 2024 · Journal Article
Pascart T, Latourte A, Tedeschi SK, Dalbeth N, et al.
📚 10 cit.🎯 RCR 2.70🔬→🩺 Translationnel - Butterfly vertebra
Joint bone spine · 2023 · Journal Article
Vivier M, Attane G, Fabre S, Lioté F
- Position statement on the diagnosis and management of acromegaly: The French National Diagnosis and Treatment Protocol (NDTP)
Annales d'endocrinologie · 2023 · Journal Article
Brue T, Rahabi H, Barry A, Barlier A, et al.
📚 11 cit.🎯 RCR 1.81 - Ten-year radiographic and functional outcomes in rheumatoid arthritis patients in remission compared to patients in low disease activity
Arthritis research & therapy · 2023 · Journal Article
Ruyssen-Witrand A, Guernec G, Dupont J, Lapuyade D, et al.
📚 5 cit.🎯 RCR 1.11🔬→🩺 Translationnel - The 2023 ACR/EULAR classification criteria for calcium pyrophosphate deposition disease
Annals of the rheumatic diseases · 2023 · Journal Article
Abhishek A, Tedeschi SK, Pascart T, Latourte A, et al.
📚 41 cit.🎯 RCR 8.31🔬→🩺 Translationnel - The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease
Arthritis & rheumatology (Hoboken, N.J.) · 2023 · Journal Article
Abhishek A, Tedeschi SK, Pascart T, Latourte A, et al.
📚 55 cit.🎯 RCR 9.96🔬→🩺 Translationnel - Constriction ring syndrome: Severe cuts
Joint bone spine · 2022 · Journal Article
Pezot M, Funck-Brentano T, Lioté F
- Identifying Potential Classification Criteria for Calcium Pyrophosphate Deposition Disease: Item Generation and Item Reduction
Arthritis care & research · 2022 · Journal Article
Tedeschi SK, Pascart T, Latourte A, Godsave C, et al.
📚 19 cit.🎯 RCR 2.93🔬→🩺 Translationnel - Calcium pyrophosphate crystal deposition in a cohort of 57 patients with Gitelman syndrome
Rheumatology (Oxford, England) · 2022 · Journal Article
Chotard E, Blanchard A, Ostertag A, Latourte A, et al.
📚 17 cit.🎯 RCR 2.05 - Cut-off value to identify a flare using the Flare Assessment in Rheumatoid Arthritis (FLARE-RA) questionnaire: analysis of the TOSCA study
Rheumatology (Oxford, England) · 2021 · Clinical Trial, Phase IV
Aouad K, Gaudin P, Vittecoq O, Morel J, et al.
📚 5 cit.🩺 Clinique - 2019 EULAR points to consider for the assessment of competences in rheumatology specialty training
Annals of the rheumatic diseases · 2021 · Consensus Statement
Sivera F, Alunno A, Najm A, Avcin T, et al.
📚 7 cit. - Kawasaki-like diseases and thrombotic coagulopathy in COVID-19: delayed over-activation of the STING pathway?
Emerging microbes & infections · 2020 · Journal Article
Berthelot JM, Drouet L, Lioté F
📚 57 cit.🎯 RCR 2.73 - Lymphocyte Changes in Severe COVID-19: Delayed Over-Activation of STING?
Frontiers in immunology · 2020 · Journal Article
Berthelot JM, Lioté F, Maugars Y, Sibilia J
📚 43 cit.🎯 RCR 1.72🔬→🩺 Translationnel - Adrenomedullin and truncated peptide adrenomedullin(22-52) affect chondrocyte response to apoptotis in vitro: downregulation of FAS protects chondrocyte from cell death
Scientific reports · 2020 · Journal Article
Velard F, Chatron-Colliet A, Côme D, Ah-Kioon MD, et al.
📚 7 cit. - BCP crystals promote chondrocyte hypertrophic differentiation in OA cartilage by sequestering Wnt3a
Annals of the rheumatic diseases · 2020 · Journal Article
Bertrand J, Kräft T, Gronau T, Sherwood J, et al.
📚 41 cit.🎯 RCR 2.14 - Spondyloarthritis-Associated IgA Nephropathy
Kidney international reports · 2020 · Journal Article
Champtiaux N, Lioté F, El Karoui K, Vigneau C, et al.
📚 21 cit.🎯 RCR 1.49 - COVID-19 as a STING disorder with delayed over-secretion of interferon-beta
EBioMedicine · 2020 · Journal Article
Berthelot JM, Lioté F
📚 54 cit.🎯 RCR 2.30 - Galectin 3 Deficiency Alters Chondrocyte Primary Cilium Formation and Exacerbates Cartilage Destruction via Mitochondrial Apoptosis
International journal of molecular sciences · 2020 · Journal Article
Hafsia N, Forien M, Renaudin F, Delacour D, et al.
📚 17 cit.🎯 RCR 1.01 - Benefits of Polymerase Chain Reaction Combined With Culture for the Diagnosis of Bone and Joint Infections: A Prospective Test Performance Study
Open forum infectious diseases · 2019 · Journal Article
Jacquier H, Fihman V, Amarsy R, Vicaut E, et al.
📚 16 cit.🎯 RCR 1.32🔬→🩺 Translationnel
Goutte17
▼
Goutte17
▼- Time-course of tophus resolution on Dual-energy CT and ultrasound after 24months of a treat-to-target strategy: Results from GOUT-DECTUS study
Joint bone spine · 2025 · Journal Article
Pascart T, Richette P, Bousson V, Ottaviani S, et al.
📚 3 cit. - Publisher Correction: A genome-wide association analysis reveals new pathogenic pathways in gout
Nature genetics · 2024 · Published Erratum
Major TJ, Takei R, Matsuo H, Leask MP, et al.
📚 4 cit. - A genome-wide association analysis reveals new pathogenic pathways in gout
Nature genetics · 2024 · Journal Article
Major TJ, Takei R, Matsuo H, Leask MP, et al.
📚 55 cit.🎯 RCR 10.41 - Systemic inflammatory cytokine profiles in patients with gout during flare, intercritical and treat-to-target phases: TNFSF14 as new biomarker
Annals of the rheumatic diseases · 2024 · Journal Article
Ea HK, Kischkel B, Chirayath TW, Klück V, et al.
📚 22 cit.🎯 RCR 4.42🔬→🩺 Translationnel - The clinical benefits of sodium-glucose cotransporter type 2 inhibitors in people with gout
Nature reviews. Rheumatology · 2024 · Journal Article
Yokose C, McCormick N, Abhishek A, Dalbeth N, et al.
📚 21 cit.🎯 RCR 5.28🔬→🩺 Translationnel - Mechanisms and rationale for uricase use in patients with gout
Nature reviews. Rheumatology · 2023 · Journal Article
Schlesinger N, Pérez-Ruiz F, Lioté F
📚 70 cit.🎯 RCR 10.28🔬→🩺 Translationnel - Association of Gout Polygenic Risk Score With Age at Disease Onset and Tophaceous Disease in European and Polynesian Men With Gout
Arthritis & rheumatology (Hoboken, N.J.) · 2023 · Journal Article
Sumpter NA, Takei R, Cadzow M, Topless RKG, et al.
📚 18 cit.🎯 RCR 2.70🔬→🩺 Translationnel - Simple Application and Adherence to Gout Guidelines Enables Disease Control: An Observational Study in French Referral Centres
Journal of clinical medicine · 2022 · Journal Article
Jauffret C, Ottaviani S, Latourte A, Ea HK, et al.
📚 3 cit. - Distribution of bony erosions in feet and performance of two bone erosion scores: A dual-energy computed tomography study of 61 patients with gout
PloS one · 2021 · Journal Article
Chabernaud Negrier A, Taihi L, Vicaut E, Richette P, et al.
📚 1 cit. - UltraSound evaluation in follow-up of urate-lowering therapy in gout phase 2 (USEFUL-2): Duration of flare prophylaxis
Joint bone spine · 2020 · Clinical Trial, Phase II
Ebstein E, Forien M, Norkuviene E, Richette P, et al.
📚 23 cit.🎯 RCR 1.83🩺 Clinique - Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages
Annals of the rheumatic diseases · 2020 · Journal Article
Renaudin F, Orliaguet L, Castelli F, Fenaille F, et al.
📚 131 cit.🎯 RCR 6.22🔬→🩺 Translationnel - 2020 Recommendations from the French Society of Rheumatology for the management of gout: Management of acute flares
Joint bone spine · 2020 · Journal Article
Latourte A, Pascart T, Flipo RM, Chalès G, et al.
📚 22 cit.🎯 RCR 1.53🔬→🩺 Translationnel - 2020 recommendations from the French Society of Rheumatology for the management of gout: Urate-lowering therapy
Joint bone spine · 2020 · Journal Article
Pascart T, Latourte A, Flipo RM, Chalès G, et al.
📚 37 cit.🎯 RCR 2.84🔬→🩺 Translationnel - 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout
Annals of the rheumatic diseases · 2020 · Consensus Statement
Richette P, Doherty M, Pascual E, Barskova V, et al.
📚 267 cit.🎯 RCR 19.12🩺 Clinique - Patients With Early-Onset Gout and Development of Earlier Severe Joint Involvement and Metabolic Comorbid Conditions: Results From a Cross-Sectional Epidemiologic Survey
Arthritis care & research · 2019 · Comparative Study
Pascart T, Norberciak L, Ea HK, Guggenbuhl P, et al.
📚 24 cit.🎯 RCR 1.31🔬→🩺 Translationnel - Difficult-to-treat gout flares: eligibility for interleukin-1 inhibition in private practice is uncommon according to current EMA approval
Rheumatology (Oxford, England) · 2019 · Journal Article
Pascart T, Norberciak L, Ea HK, Graf S, et al.
📚 19 cit.🎯 RCR 1.07🔬→🩺 Translationnel - Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout
Annals of the rheumatic diseases · 2019 · Journal Article
Bursill D, Taylor WJ, Terkeltaub R, Abhishek A, et al.
📚 82 cit.🎯 RCR 5.11🔬→🩺 Translationnel
csDMARDs5
▼
csDMARDs5
▼- Effect of a 1-month methotrexate delay on pneumococcal vaccine immunogenicity and disease control in patients with early rheumatoid arthritis (VACIMRA): an open-label randomised trial
The Lancet. Rheumatology · 2025 · Journal Article
Morel J, Dernis E, Roux C, Richez C, et al.
📚 2 cit.🩺 Clinique - Methotrexate osteopathy in rheumatoid arthritis
Joint bone spine · 2025 · Journal Article
Lioté F, Paycha F
- Methotrexate also improves rheumatoid arthritis through correction of microbiota dysbiosis
Joint bone spine · 2023 · Editorial
Berthelot JM, Lioté F, Sibilia J
📚 8 cit.🎯 RCR 1.18🔬→🩺 Translationnel - Busting the myth of methotrexate chronic hepatotoxicity
Nature reviews. Rheumatology · 2023 · Journal Article
Di Martino V, Verhoeven DW, Verhoeven F, Aubin F, et al.
📚 57 cit.🎯 RCR 9.56 - Hydroxychloroquine levels in patients with systemic lupus erythematosus: whole blood is preferable but serum levels also detect non-adherence
Arthritis research & therapy · 2020 · Journal Article
Blanchet B, Jallouli M, Allard M, Ghillani-Dalbin P, et al.
📚 23 cit.🎯 RCR 1.38🔬→🩺 Translationnel
Biothérapies non-anti-TNF3
▼
Biothérapies non-anti-TNF3
▼- Towards the Lowest Efficacious Dose: Results From a Multicenter Noninferiority Randomized Open-Label Controlled Trial Assessing Tocilizumab or Abatacept Injection Spacing in Rheumatoid Arthritis in Remission
Arthritis & rheumatology (Hoboken, N.J.) · 2024 · Randomized Controlled Trial
Kedra J, Dieudé P, Giboin C, Marotte H, et al.
📚 3 cit.🩺 Clinique - Increased high molecular weight adiponectin and lean mass during tocilizumab treatment in patients with rheumatoid arthritis: a 12-month multicentre study
Arthritis research & therapy · 2020 · Journal Article
Toussirot E, Marotte H, Mulleman D, Cormier G, et al.
📚 40 cit.🎯 RCR 2.64🔬→🩺 Translationnel - Tocilizumab in symptomatic calcium pyrophosphate deposition disease: a pilot study
Annals of the rheumatic diseases · 2020 · Clinical Trial
Latourte A, Ea HK, Frazier A, Blanchard A, et al.
📚 16 cit.🎯 RCR 1.09🩺 Clinique
CPPD1
▼
CPPD1
▼- Adsorption of Proteins on m-CPPD and Urate Crystals Inhibits Crystal-induced Cell Responses: Study on Albumin-crystal Interaction
Journal of functional biomaterials · 2019 · Journal Article
Renaudin F, Sarda S, Campillo-Gimenez L, Séverac C, et al.
📚 15 cit.
Lupus1
▼
Lupus1
▼- Hydroxychloroquine levels in patients with systemic lupus erythematosus: whole blood is preferable but serum levels also detect non-adherence
Arthritis research & therapy · 2020 · Journal Article
Blanchet B, Jallouli M, Allard M, Ghillani-Dalbin P, et al.
📚 23 cit.🎯 RCR 1.38🔬→🩺 Translationnel
Microbiote1
▼
Microbiote1
▼- Tissue microbiota: A 'secondary-self', first target of autoimmunity?
Joint bone spine · 2022 · Editorial
Berthelot JM, Lioté F, Sibilia J
📚 4 cit.
Rhumatisme psoriasique1
▼
Rhumatisme psoriasique1
▼- A prospective survey on therapeutic inertia in psoriatic arthritis (OPTI'PsA)
Rheumatology (Oxford, England) · 2024 · Journal Article
Lioté F, Constantin A, Dahan É, Quiniou JB, et al.
📚 3 cit.🎯 RCR 1.12🔬→🩺 Translationnel
Vraie vie / RWE1
▼
Vraie vie / RWE1
▼- Effectiveness of topical sodium thiosulfate for ectopic calcifications and ossifications. Results of the CATSS-O study
Seminars in arthritis and rheumatism · 2023 · Journal Article
Gauffenic A, Ratsimbazafy V, Ostertag A, Linglart A, et al.
📚 7 cit.🎯 RCR 1.42