Mme Docteur MARIE-CHRISTINE LEGOUFFE

Thèses universitaires

• Syndrome de Gougerot-Sjögren et virus de l'hépatite C

  1994
  Médecine🎓 Montpellier 1

  Direction : Jacques Sany

Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.

Localisation des cabinets

Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.

Lieux de consultation

• CABINET DU DR MARIE-CHRISTINE LEGOUFFE

  16 AVENUE D ASSAS, 34000 Montpellier

  Libéral
  171 m171 m171 m171 m

  © OpenStreetMap · Photos Wikimedia Commons (CC)

  📷 Street View ↗🗺️ Maps ↗OSM ↗

• CABINET DU DR MARIE-CHRISTINE LEGOUFFE

  POLE SANTE N106 — 280 AVENUE DE LODEVE, 34150 Gignac

  ☎ 0467575283Libéral
  156 m246 m

  © OpenStreetMap · Photos Wikimedia Commons (CC)

  📷 Street View ↗🗺️ Maps ↗OSM ↗

• HOPITAL LAPEYRONIE CHU MONTPELLIER

  371 Avenue DU DOYEN GASTON GIRAUD, 34295 Montpellier

  ☎ 0467336733Hospitalier🏥 Centre CHU ↗🏥 Voir cet établissement
  127 m171 m

  © OpenStreetMap · Photos Wikimedia Commons (CC)

  📷 Street View ↗🗺️ Maps ↗OSM ↗

Tarifs & secteur de conventionnement

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

• 1

  Sicca syndrome associated with hepatitis C virus infection

  Arthritis and rheumatism · 1996

  📚 116 citations🎯 RCR 4.69Top 9% NIH

  Lire l'abstract Crossref ↓

  AbstractObjective. To determine the prevalence of hepatitis C virus (HCV) infection in patients with sicca syndrome, and to determine the clinical, immunologic, and genetic characteristics of sicca syndrome associated with HCV.Methods. We conducted a prospective study in a university hospital immunology–rheumatology department. Sixty‐two consecutive patients with sicca syndrome according to the European criteria for Sjögren's syndrome were included. HCV infection was diagnosed in patients with positive recombinant immunoblot assay findings and the presence of viral RNA in serum and saliva. Rheumatoid factor (RF), cryoglobulins, antinuclear antibodies, and anti–SS‐A/SS‐B antibodies were sought. HLA typing was performed on all patients.Results. The prevalence of HCV infection in patients with sicca syndrome was 19%. The incidence of neurologic involvement was significantly increased in patients with sicca syndrome associated with HCV infection (24% versus 4%; P < 0.03), as was elevations in transaminase levels (87.5% versus 16%; P < 0.0001). RF and cryoglobulins were more frequent in HCV‐positive sicca syndrome patients (62% versus 30%; P < 0.03, and 56% versus 10%; P < 0.001, respectively). In contrast, anti–SS‐A/SS‐B antibodies were present in 38% of HCV‐negative sicca syndrome patients, but in only 1 HCV‐positive sicca syndrome patient (P < 0.01). No significant difference in HLA type was observed. Viral RNA was present in the saliva of 83% of HCV‐positive sicca syndrome patients, but in none of the HCV‐negative sicca syndrome patients.Conclusion. We observed a high prevalence of HCV infection in our patients with sicca syndrome. HCV‐positive sicca syndrome patients had specific clinical characteristics and were seronegative for SS–A/SS‐B antibodies. Moreover, HCV RNA was present in the saliva of patients with HCV‐associated sicca syndrome.

• 2

  Treatment of chronic knee synovitis with arthroscopic synovectomy: longterm results

  The Journal of rheumatology · 2002

  📚 33 citations🎯 RCR 1.32
• 3

  IgA isotype rheumatoid factor in rheumatoid arthritis: clinical implications

  Clinical and experimental rheumatology · 1996

  📚 25 citations

Publications scientifiques (4) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Partager cette fiche